Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Fura 2-AM (Fura 2) is a calcium-specific ratio-metric fluorescent dye. It is also known as acetoxy-methyl-ester. In response to calcium ions, ratio metric dyes like Fura 2 changes their respective excitation or emission spectra. The intracellular calcium concentration is determined by the fluorescence emission ratio or excitation at distinct wavelengths. Fura 2 has an emission peak at 505 nm, and the excitation peak ranges between 340 to 380 nm and is the preferred calcium indicator.
Artikel-Nr:
(BNUM1228-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1228-50
Lokale Artikelnummer::
BTIUBNUM1228-50
Beschreibung:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
VE:
1 * 50 µl
Lieferant:
Biotium
Beschreibung:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Lieferant:
Biotium
Beschreibung:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Artikel-Nr:
(ACRO441095000)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
441095000
Lokale Artikelnummer::
ACRO441095000
Beschreibung:
(S)-N-Fmoc-α-methyl-2-fluorophenylalanine 98%, 98% ee
VE:
1 * 500 mg
Artikel-Nr:
(APOSOR480411-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR480411-1G
Lokale Artikelnummer::
APOSOR480411-1G
Beschreibung:
3-Phenyl-L-serine 95%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-8585R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8585R-A555
Lokale Artikelnummer::
BOSSBS-8585R-A555
Beschreibung:
Arginase I which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster. Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location. Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein. In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11061R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11061R-HRP
Lokale Artikelnummer::
BOSSBS-11061R-HRP
Beschreibung:
OLFM3 is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5134R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5134R-A555
Lokale Artikelnummer::
BOSSBS-5134R-A555
Beschreibung:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq].
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Artikel-Nr:
(BOSSBS-6659R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6659R-HRP
Lokale Artikelnummer::
BOSSBS-6659R-HRP
Beschreibung:
Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
VE:
1 * 100 µl
Artikel-Nr:
(AVIVARP43518T10025)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
ARP43518T10025
Lokale Artikelnummer::
AVIVARP43518T10025
Beschreibung:
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
VE:
1 * 25 µl
Lieferant:
Alfa Aesar
Beschreibung:
Azomethin H Natriumsalz Hydrat
Artikel-Nr:
(BSENR-1492-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1492-50
Lokale Artikelnummer::
BSENR-1492-50
Beschreibung:
Human beta-endorphin is a 31 amino acid peptide cleaved from the precursor pro-opiomelanocortin (POMC). It is an endogenous opioid peptide neurotransmitter that interacts with opioid receptors.
VE:
1 * 50 µG
Artikel-Nr:
(BWRLBS3850)
Lieferant:
Bioworld Technology
Hersteller-Artikelnummer::
BS3850
Lokale Artikelnummer::
BWRLBS3850
Beschreibung:
Synthetic peptide, corresponding to amino acids 1060-1110 of Human DNA pol delta cat.
VE:
1 * 100 µG
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Fmoc-3,4-dichloro-L-phenylalanine 95%
Preis auf Anfrage
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