2\'-Amino-4\',5\'-dimethoxyacetophenon
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Chlor-2-nitroanisol 98%
Lieferant:
Alfa Aesar
Beschreibung:
2-Isobutyl-3-methoxypyrazin ≥98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Methyl-6-(trifluoromethyl)-1H-indol-5-yl ether
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Methyl-4-brom-3-methoxy-2-thiophencarboxylat 97%
Lieferant:
Alfa Aesar
Beschreibung:
2-Nitroanisol ≥99%
Lieferant:
Honeywell Chemicals
Beschreibung:
Ammoniumcarbonat ≥30,0% (NH₃-Basis) ACS, Fluka™
Artikel-Nr:
(BOSSBS-13544R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13544R-A350
Lokale Artikelnummer::
BOSSBS-13544R-A350
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13544R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13544R-A488
Lokale Artikelnummer::
BOSSBS-13544R-A488
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
VE:
1 * 100 µl
Lieferant:
Serva
Beschreibung:
Natriumhydrogencarbonat
Artikel-Nr:
(SIAL325767-100G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
325767-100G
Lokale Artikelnummer::
SIAL325767-100G
Beschreibung:
Lanthan(III)carbonat Hydrat, Sigma-Aldrich®
VE:
1 * 100 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Acetoxy-4-methoxybenzeneboronic acid, pinacol ester
Artikel-Nr:
(APOSPC0504-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC0504-1G
Lokale Artikelnummer::
APOSPC0504-1G
Beschreibung:
Fmoc-3,4,5-trifluoro-D-phenylalanine
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
MAPK/ERK Signalling Pathway
Artikel-Nr:
(PRSI29-708)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-708
Lokale Artikelnummer::
PRSI29-708
Beschreibung:
CA8 was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, CA8 lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). CA8 continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family.The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-744)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-744
Lokale Artikelnummer::
PRSI25-744
Beschreibung:
CA8 was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, CA8 lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). CA8 continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
VE:
1 * 50 µG
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||