5-Amino-2-nitrobenzoes\\\\\\\\\\\\\\\\u00E4ure
Lieferant:
Thermo Scientific
Beschreibung:
3-Amino-p-toluylsäure
Lieferant:
Thermo Scientific
Beschreibung:
2-Amino-5-chlorbenzamid
Artikel-Nr:
(BOSSBS-13138R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13138R-FITC
Lokale Artikelnummer::
BOSSBS-13138R-FITC
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. At least eight complementation groups (A-G) have been identified and six FA genes (for subtypes A, C, D2, E, F and G) have been cloned. The FA proteins lack sequence homologies or motifs that could point to a molecular function. The cellular accumulation of FA proteins, including FANCA and FANCG, is subject to regulation by TNF alpha signaling. Phosphorylation of FANC (Fanconi anemia complementation group) proteins is thought to be important for the function of the FA pathway. FANCA, also known as FACA and FANCH, associates with the Brm-related gene 1 (BRG1) product, a subunit of the SWI/SNF complex which remodels chromatin structure through a DNA-dependent ATPase activity. FANCA is mainly expressed in lymphoid tissues, testis and ovary. The amino-terminal region of the FANCA protein is required for FANCG binding, FANCC binding, nuclear localization and functional activity of the complex. The human FANCA gene maps to chromosome 16q24.3 and encodes a 1,455 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13138R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13138R-A488
Lokale Artikelnummer::
BOSSBS-13138R-A488
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. At least eight complementation groups (A-G) have been identified and six FA genes (for subtypes A, C, D2, E, F and G) have been cloned. The FA proteins lack sequence homologies or motifs that could point to a molecular function. The cellular accumulation of FA proteins, including FANCA and FANCG, is subject to regulation by TNF alpha signaling. Phosphorylation of FANC (Fanconi anemia complementation group) proteins is thought to be important for the function of the FA pathway. FANCA, also known as FACA and FANCH, associates with the Brm-related gene 1 (BRG1) product, a subunit of the SWI/SNF complex which remodels chromatin structure through a DNA-dependent ATPase activity. FANCA is mainly expressed in lymphoid tissues, testis and ovary. The amino-terminal region of the FANCA protein is required for FANCG binding, FANCC binding, nuclear localization and functional activity of the complex. The human FANCA gene maps to chromosome 16q24.3 and encodes a 1,455 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(EHERC10225000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C10225000
Lokale Artikelnummer::
EHERC10225000
Beschreibung:
4-Amino-2-methylchinolin
VE:
1 * 0,1 g
Artikel-Nr:
(BOSSBS-11959R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11959R-A750
Lokale Artikelnummer::
BOSSBS-11959R-A750
Beschreibung:
The leucine-rich (LRR) repeat is a 20 to 30 amino acid motif that forms a hydrophobic å/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK5 (SLIT and NTRK-like family, member 5), also known as LRRC11 (leucine-rich repeat-containing protein 11), is a 958 amino acid single-pass type I membrane protein that contains 16 LRR repeats and belongs to the SLITRK family. Expressed at high levels in the cerebral cortex, but also present in areas of the spinal cord and medulla, SLITRK5 functions to suppress neurite outgrowth, thereby playing a regulatory role in neuronal function. The gene encoding SLITRK5 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11959R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11959R-CY3
Lokale Artikelnummer::
BOSSBS-11959R-CY3
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK5 (SLIT and NTRK-like family, member 5), also known as LRRC11 (leucine-rich repeat-containing protein 11), is a 958 amino acid single-pass type I membrane protein that contains 16 LRR repeats and belongs to the SLITRK family. Expressed at high levels in the cerebral cortex, but also present in areas of the spinal cord and medulla, SLITRK5 functions to suppress neurite outgrowth, thereby playing a regulatory role in neuronal function. The gene encoding SLITRK5 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
VE:
1 * 100 µl
Artikel-Nr:
(MOLEM43883839)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M43883839
Lokale Artikelnummer::
MOLEM43883839
Beschreibung:
2-Amino-6-brompyridin
VE:
1 * 5 g
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Artikel-Nr:
(FLUO015547-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
015547-1G
Lokale Artikelnummer::
FLUO015547-1G
Beschreibung:
8-Amino-5-bromchinolin
VE:
1 * 1 g
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Lieferant:
FLUOROCHEM
Beschreibung:
2-Amino-6-fluorpyridin
Lieferant:
FLUOROCHEM
Beschreibung:
2-Amino-4-methyloxazol
Artikel-Nr:
(BOSSBS-1288G-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1288G-A350
Lokale Artikelnummer::
BOSSBS-1288G-A350
Beschreibung:
Myostatin (GDF8)is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor beta superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1288G-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1288G-CY7
Lokale Artikelnummer::
BOSSBS-1288G-CY7
Beschreibung:
Myostatin (GDF8)is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor beta superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10459R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10459R-CY3
Lokale Artikelnummer::
BOSSBS-10459R-CY3
Beschreibung:
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1288G-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1288G-CY3
Lokale Artikelnummer::
BOSSBS-1288G-CY3
Beschreibung:
Myostatin (GDF8)is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor beta superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15462R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15462R-A647
Lokale Artikelnummer::
BOSSBS-15462R-A647
Beschreibung:
HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyse the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
VE:
1 * 100 µl
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