4-Hydroxy-2,3,5-trifluorobenzoic+acid
Artikel-Nr:
(BOSSBS-10662R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10662R-A680
Lokale Artikelnummer::
BOSSBS-10662R-A680
Beschreibung:
Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP Signalling cascade. Required for GDF2/BMP9 Signalling through SMAD1 in endothelial cells and modulates TGF-beta1 Signalling through SMAD3.
VE:
1 * 100 µl
Artikel-Nr:
(ABCAAB196646-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB196646-100
Lokale Artikelnummer::
ABCAAB196646-100
Beschreibung:
Anti-p38 beta/MAPK11+p38 alpha/MAPK14 Rabbit Monoclonal Antibody [clone: Y122] (Alexa Fluor® 647)
VE:
1 * 100 µl
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Artikel-Nr:
(BOSSBS-4532R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4532R-HRP
Lokale Artikelnummer::
BOSSBS-4532R-HRP
Beschreibung:
Clenbuterol belongs to the group of agonists. In livestock production clenbuterol improves the meat/fat ratio in fattened animals or accelerate the growth. Up to now agonists have not been authorized as adjuvants for fattening. In addition to its lipolytic and anabolic effect, clenbuterol has a relaxing effect on non-striated musculature on which is based its therapeutic use as an antiasthmatic and a tocolytic agent. When employed as a fattening adjuvant, as compared with the therapeutic use, clenbuterol is administered in a 5 to 10 times higher dose. Therefore, it is possible that clenbuterol residues may lead to a risk for consumers after illegal administration.Using the clenbuterol monocalantibody, it is possible to detect clenbuterol and other agonists in urine, muscle and liver both rapidly and with accuracy. Clenbuterol is a long acting beta 2 adrenergic agonist. Like other beta 2 agonists, clenbuterol is believed to act by stimulating production of cyclic AMP through the activation of adenyl cyclase. By definition, Beta 2 agonists have more smooth muscle relaxation activity (bronchial, vascular and uterine smooth muscle) versus its cardiac effects (Beta 1).
VE:
1 * 100 µl
Artikel-Nr:
(USBI129348)
Lieferant:
US Biological
Hersteller-Artikelnummer::
129348
Lokale Artikelnummer::
USBI129348
Beschreibung:
Anti-MANBA Mouse Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-13148R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13148R-FITC
Lokale Artikelnummer::
BOSSBS-13148R-FITC
Beschreibung:
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. A wide range of enzymes facilitate in the proteolytic Ub pathway, including monoclonal nonspecific suppressor factor-beta (MNSF-beta), a subunit of MNSF, which is a lymphokine product of a murine T cell hybrid-oma that restricts the production of LPS-induced immunoglobulin secreting cells in an antigen-nonspecific manner. MNSF-beta is a ubiquitin-like fusion protein consisting of the ribosomal protein S30 and a protein that shares 36% sequence identity with ubiquitin. This ubiquitin-like segment (Ubi-L) can be cleaved from MNSF-beta in the cytosol.
VE:
1 * 100 µl
Lieferant:
MP Biomedicals
Beschreibung:
Kojic acid is used as an antibiotic reagent. It is tyrosinase inhibitor. Kojic acid is a chelation agent.
Lieferant:
Alfa Aesar
Beschreibung:
2-Naphthaldehyd ≥98%
Artikel-Nr:
(BOSSBS-5018R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5018R-FITC
Lokale Artikelnummer::
BOSSBS-5018R-FITC
Beschreibung:
ACADVL (acyl-Coenzyme A dehydrogenase, very long chain) catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5018R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5018R-A750
Lokale Artikelnummer::
BOSSBS-5018R-A750
Beschreibung:
ACADVL (acyl-Coenzyme A dehydrogenase, very long chain) catalyses the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2601R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2601R-HRP
Lokale Artikelnummer::
BOSSBS-2601R-HRP
Beschreibung:
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3582R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3582R
Lokale Artikelnummer::
BOSSBS-3582R
Beschreibung:
Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1157R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1157R-A680
Lokale Artikelnummer::
BOSSBS-1157R-A680
Beschreibung:
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1157R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1157R-A488
Lokale Artikelnummer::
BOSSBS-1157R-A488
Beschreibung:
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1157R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1157R-A647
Lokale Artikelnummer::
BOSSBS-1157R-A647
Beschreibung:
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
VE:
1 * 100 µl
Artikel-Nr:
(BSBTA01716-2)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
A01716-2
Lokale Artikelnummer::
BSBTA01716-2
Beschreibung:
Rabbit IgG polyclonal antibody for Interferon gamma receptor 1(IFNGR1) detection. Tested with WB in Human.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-3236R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3236R-CY5
Lokale Artikelnummer::
BOSSBS-3236R-CY5
Beschreibung:
Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
VE:
1 * 100 µl
Preis auf Anfrage
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