3,5,7-Trifluoroadamantane-1-carboxylic+acid
Artikel-Nr:
(SIAL206229-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
206229-5G
Lokale Artikelnummer::
SIAL206229-5G
Beschreibung:
Ruthenium(III)chlorid Hydrat, ReagentPlus®
VE:
1 * 5 g
Lieferant:
MP Biomedicals
Beschreibung:
Staurosporine is provided in a lyophilised form. It may be reconstituted by dissolving the lyophilised reagent in DMSO (5 mg/ml - clear, colourless solution), DMF, ethyl acetate (5 mg/ml - clear colourless solution) or methanol. Stock solutions should be further diluted with aqueous buffers just prior to use. Stability depends upon the quality of solvent used. The compound should be stored at −20 °C in the dark.
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
A cell-permeable, potent, selective, peptidomimetic, non-transition-state analog inhibitor of γ-secretase and Notch processing (IC₅₀=300 pM for Aβ₄₀ in CHO cells overexpressing wild type βAPP; 240 pM for Aβ₄₀, 370 pM for Aβ₄₂, and 320 pM for NICD, respectively, in HEK293 cells stably transfected with βAPP₆₉₅
and mNotchδE; 100 pM for both Aβ₄₀ and Aβ₄₂ in SH-SY5Y cells stably transfected with SPA4CT).
Artikel-Nr:
(PRSI26-278)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-278
Lokale Artikelnummer::
PRSI26-278
Beschreibung:
AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
Kupfer(II)phthalocyanin 90% (Farbstoffgehalt) β-form, Sigma-Aldrich®
Artikel-Nr:
(PRSI7601)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7601
Lokale Artikelnummer::
PRSI7601
Beschreibung:
TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development. TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species. TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage. TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus (1,4).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI92-394)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-394
Lokale Artikelnummer::
PRSI92-394
Beschreibung:
lysozyme C is a secreted protein and belongs to the glycosyl hydrolase 22 family. Lysozymes have primarily a bacteriolytic function, damage bacterial cell walls by catalyzing hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. Those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lysozyme C is capable of both hydrolysis and transglycosylation; it shows also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-303)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-303
Lokale Artikelnummer::
PRSI33-303
Beschreibung:
Recognises a protein of 55 kDa, identified as Cluster of Differentiation 14 (also known lipopolysaccharide receptor or LPSR). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. It is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI29-557)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-557
Lokale Artikelnummer::
PRSI29-557
Beschreibung:
ASS catalyzes the penultimate step of the arginine biosynthetic pathway.The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-302)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-302
Lokale Artikelnummer::
PRSI33-302
Beschreibung:
Recognises a protein of 55 kDa, identified as Cluster of Differentiation 14 (also known lipopolysaccharide receptor or LPSR). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. It is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSIXP-5169BT)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5169BT
Lokale Artikelnummer::
PRSIXP-5169BT
Beschreibung:
IL-15 (14-15 kD) is a member of the four alpha-helical bundle family of cytokines. It is very similar to IL-2, except that IL-15 has an IL-15 alpha receptor subunit. IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules. This implies that IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases.
VE:
1 * 50 µG
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
Thiostrepton is a thiazole-containing peptide antibiotic that inhibits protein synthesis by preventing binding of GTP to 50S ribosomal subunit.
Lieferant:
Binder
Beschreibung:
Die Avantgarde.Line-Geräte der M-Serie verfügen über eine maximale Temperatur von 300 °C und verschiedene erweiterte Programmieroptionen machen diese Materialprüfkammern ideal für Material- und Alterungstests. Die Geräte verfügen über einen hohen Luftdurchsatz und ihre leistungsstarken Ventilatoren sorgen für eine schnelle Erwärmung.
Artikel-Nr:
(PRSI34-159)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-159
Lokale Artikelnummer::
PRSI34-159
Beschreibung:
Cyclin D1 (CCND1), one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of Cyclin D1. This antibody is useful in identifying mantle cell lymphomas (CCND1+) from CLL/SLL and follicular lymphomas (CCND1-). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express CCND1.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(SOCO371.2030)
Lieferant:
SOCOREX ISBA
Hersteller-Artikelnummer::
371.2030
Lokale Artikelnummer::
SOCO371.2030
Beschreibung:
Reusable Luer lock needles intended for safe, precise animal injections. Sharp bevel and made of stainless steel for long durability.
VE:
1 * 12 ST
Lieferant:
Honeywell Chemicals
Beschreibung:
Tetrahydrofuran ≥99,9%, BioSyn™ zur Biosynthese, für Anwendungen die einen sehr niedrigen Wassergehalt benötigen, Burdick & Jackson™
Preis auf Anfrage
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