N\'-[1-Cyclopropylaminopropylidene]hydrazinecarboxylic+acid-tert-
Artikel-Nr:
(JULA8901120)
Lieferant:
JULABO GmbH
Hersteller-Artikelnummer::
8901120
Lokale Artikelnummer::
JULA8901120
Beschreibung:
Der Booster Heater bietet die Möglichkeit, die Heizleistung von einigen MAGIO Laborthermostaten um 6 kW zu erhöhen und so deren Einsatzbereich zu erweitern. Der Booster Heater kann in einem Temperaturbereich von -50 bis 300 °C eingesetzt werden. Die intelligente Steuerung in Kombination mit MAGIO sorgt dafür, dass er in vollautomatisierte Systeme eingebunden werden kann.
VE:
1 * 1 ST
Lieferant:
GREINER BIO ONE
Beschreibung:
Hochwertiges PS. Quadratische Petrischalen mit außergewöhnlicher optischer Klarheit für die mikroskopische Analyse, hitzebeständig zur Verwendung mit heißem Agar.
Artikel-Nr:
(BSENM-1725-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1725-100
Lokale Artikelnummer::
BSENM-1725-100
Beschreibung:
MAP1A and MAP1B are microtubule-associated protein which mediate the physical interactions between microtubules and components of the cytoskeleton (probably involved in autophagosome formation). MAP1A and MAP1B each consist of a heavy chain subunit and 3 different light chain subunits (LC1, LC2 and LC3). MAP1LC3A is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor form of MAP1LC3A is cleaved by APG4/ATG4B to form the cytosolic form LC3-1. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. MAP1LC3A is most abundant in heart, brain, liver, skeletal muscle and testis but is absent in thymus and peripheral leukocytes.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-8580R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8580R-HRP
Lokale Artikelnummer::
BOSSBS-8580R-HRP
Beschreibung:
GRAMD3 is a 432 amino acid protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 5q23.2. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11183R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11183R-A350
Lokale Artikelnummer::
BOSSBS-11183R-A350
Beschreibung:
Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9021R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9021R-HRP
Lokale Artikelnummer::
BOSSBS-9021R-HRP
Beschreibung:
IQCJ (IQ domain-containing protein J) is a 159 amino acid protein that contains one IQ domain. Existing as four alternatively spliced isoforms, the gene encoding IQCJ maps to human chromosome 3q25.32. Chromosome 3 houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11623R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11623R-FITC
Lokale Artikelnummer::
BOSSBS-11623R-FITC
Beschreibung:
PIRT is a 137 amino acid multi-pass membrane protein. Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain. Although PIRT is expressed in peripheral nervous system, with highest levels in dorsal root ganglion and trigeminal neurons, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord. PIRT is a required component of the VR1 complex, which positively regulates VR1, a sensor of both noxious heat and capsaicin. Correspondingly, PIRT knockout results in impaired responses to noxious heat and capsaicin exposure, while VR1 remains unaltered. The gene that encodes PIRT maps to human chromosome 17p13.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11183R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11183R-A647
Lokale Artikelnummer::
BOSSBS-11183R-A647
Beschreibung:
Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10392R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10392R-HRP
Lokale Artikelnummer::
BOSSBS-10392R-HRP
Beschreibung:
The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. SynGAP (for synaptic GTPase activating protein), a novel synaptic RasGAP, is a brain-specific protein abundant in the cortex, hippocampus and olfactory bulb. SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins. It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors. SynGAP may be involved in the regulation of BDNF as well as Ras signaling. Its activity is inhibited by phosphorylation by CaMKII, which could result in the activation of the MAP kinase pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12927R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12927R-A647
Lokale Artikelnummer::
BOSSBS-12927R-A647
Beschreibung:
Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12927R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12927R-FITC
Lokale Artikelnummer::
BOSSBS-12927R-FITC
Beschreibung:
Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP20A1 (cytochrome P450, family 20, subfamily A, polypeptide 1), also known as CYP-M, is a 462 amino acid single-pass membrane protein that belongs to the cytochrome P450 family. CYP20A1 is thought to carry its own oxygen as it lacks a conserved I-helix motif and one amino acid of its conserved heme binding site.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11623R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11623R-HRP
Lokale Artikelnummer::
BOSSBS-11623R-HRP
Beschreibung:
PIRT is a 137 amino acid multi-pass membrane protein. Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain. Although PIRT is expressed in peripheral nervous system, with highest levels in dorsal root ganglion and trigeminal neurons, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord. PIRT is a required component of the VR1 complex, which positively regulates VR1, a sensor of both noxious heat and capsaicin. Correspondingly, PIRT knockout results in impaired responses to noxious heat and capsaicin exposure, while VR1 remains unaltered. The gene that encodes PIRT maps to human chromosome 17p13.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11271R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11271R-A488
Lokale Artikelnummer::
BOSSBS-11271R-A488
Beschreibung:
Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11271R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11271R-A647
Lokale Artikelnummer::
BOSSBS-11271R-A647
Beschreibung:
Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11271R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11271R-A350
Lokale Artikelnummer::
BOSSBS-11271R-A350
Beschreibung:
Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11183R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11183R-A488
Lokale Artikelnummer::
BOSSBS-11183R-A488
Beschreibung:
Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness.
VE:
1 * 100 µl
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