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4,4-Dimethylcyclohexa-1,5-dienylborons\\\\\\\\u00E4ure+Mononatriu
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4,4-Dimethylcyclohexa-1,5-dienylborons\\\\\\\\u00E4ure+Mononatriu
Artikel-Nr:
(BOSSBS-12228R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12228R-CY5
Lokale Artikelnummer::
BOSSBS-12228R-CY5
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 568 (ZNF568) is a 644 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF568 contains fifteen C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation. Two isoforms of ZNF568 exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4272R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4272R
Lokale Artikelnummer::
BOSSBS-4272R
Beschreibung:
A number of human cancers are sensitive to mitotic stress, implying checkpoint defects. Many proteins that contain forkhead-associated (FHA) domains are cell cycle checkpoints and CHFR is one such protein. It has a FHA and ring finger domain within its N terminus. Within its C terminus, CHFR contains a cysteine-rich region that did not display significant similarity to any protein in the GenBank database, but is highly conserved between humans and mice. It has been concluded that CHFR defines a checkpoint that delays entry into metaphase in response to mitotic stress. It has been found CpG methylation-dependent silencing of CHFR expression occurs in 45% of cancer cell lines, 40% of primary colorectal cancers, 53% of colorectal adenomas, and 30% of primary head and neck cancers.
VE:
1 * 100 µl
Lieferant:
Brady
Beschreibung:
Der M210-LAB tragbare Etikettendrucker ist ein universelles Beschriftungsgerät für Forschungs- und Schulungszwecke sowie klinische Labors. Der M210-LAB nutzt Etiketten, die speziell für harsche Umgebungen konzipiert sind. Er kann schnell (10 mm/s) und einfach lesbare Etiketten für flache, gebogene oder sehr raue Oberflächen erstellen, die über Jahre haften können, selbst wenn sie extremen Temperaturen und Chemikalien ausgesetzt sind.
Lieferant:
Thermo Scientific
Beschreibung:
1-Boc-3-fluoro-4-piperidone 97%
Lieferant:
Merck
Beschreibung:
Sauberes, reines Wasser gehört zu den wichtigsten Lebensmitteln. Auch in der Lebensmittel- und in der Pharmaindustrie ist die Untersuchung von Wasser vorgeschrieben. Granulierte Medien, die den jeweiligen Normen entsprechen, garantieren zuverlässige Ergebnisse.
Lieferant:
MP Biomedicals
Beschreibung:
2-Methylisothiazolone (MIT) are chemical compounds used as highly effective biocidal agents against fungal and bacterial species. They are widely used as a preservative in cosmetic industry, and as a pesticide, e.g. in paints and water tanks.
Lieferant:
Tonbo Biosciences
Beschreibung:
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.
Lieferant:
Tonbo Biosciences
Beschreibung:
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.
Lieferant:
GREINER BIO ONE
Beschreibung:
Cycloolefin, black pigmented frame, 190 μm ultra-clear film bottom, tissue culture treated, sterile. SCREENSTAR microplates are specialised products for sophisticated microscopic applications, like high content screening (HCS) or high resolution microscopy with water and oil immersion objectives.
Lieferant:
VWR Collection
Beschreibung:
Diese Einweg-Labormäntel aus PP-Vlies verfügen über einen spitz zulaufenden Kragen und eine Brusttasche. Ideal für nicht kritische Anwendungen.
Lieferant:
Tonbo Biosciences
Beschreibung:
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.
Artikel-Nr:
(BLDPBD152837-25G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD152837-25G
Lokale Artikelnummer::
BLDPBD152837-25G
Beschreibung:
1-Boc-3-fluoro-4-piperidone 97%
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-1466R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1466R-A555
Lokale Artikelnummer::
BOSSBS-1466R-A555
Beschreibung:
Nck is a highly conserved, oncogenic protein. It is a common target for the action of different surface receptors, encoding one SH2 and three SH3 domains, the Src homology motifs found in nonreceptor tyrosine kinases, Ras GTPase activating protein, phosphatidylinositol 3 kinase, and phospholipase Cg. Nck is widely expressed in various tissues and in cell lines from human, murine, and rat origins. Nck is phosphorylated on tyrosine, serine, and threonine residues in response to stimulation of EGF and PDGF in A431 and NIH 3T3 cells respectively. Like other SH2 containing proteins, Nck is associated with tyrosine autophosphorylated EGF or PDGF receptors via its SH2 domain. Overexpression of Nck leads to transformation of NIH 3T3 cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6710R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6710R-A680
Lokale Artikelnummer::
BOSSBS-6710R-A680
Beschreibung:
NGL-1 is a single pass type I membrane protein that acts as a cell adhesion molecule. It contains nine leucine-rich repeats (LRR) and one Ig-like C2-type domain. NGL-1 is predominantly expressed in the striatum and the cerebral cortex of both the embryonic and adult brain. NGL-1 specifically interacts with Netrin G1 (a molecule involved in axon guidance in the developing central nervous system) via its LRR region. NGL-1 plays a role in the regulation of neurite outgrowth of developing thalamic neurons. Soluble NGL-1 inhibits thalamic axon outgrowth while NGL-1 that is bound to the surface of developing thalamocortical axons stimulates growth. NGL-1 also interacts with Whirlin possibly stablising interstereociliar links.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12872R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12872R-A488
Lokale Artikelnummer::
BOSSBS-12872R-A488
Beschreibung:
Bloom’s syndrome is an autosomal recessive disorder characterized by pre- and post-natal growth deficiencies, sun sensitivity, immunodeficiency and a predisposition to various cancers. The gene responsible for Bloom’s syndrome, BLM, encodes a protein homologous to the RecQ helicase of E. coli and is mutated in most Bloom’s syndrome patients. One characteristic of Bloom’s syndrome is an increased frequency of sister chromatid exchange (SCE). BLM has been shown to unwind G4 DNA, and a failure of this function is thought to be responsible for the increased rate of SCE. BLM is known to be translocated to the nucleus, where its ATPase activity is stimulated by both single- and double-stranded DNA. Mutations in the yeast SGS1, a homolog of BLM, are known to cause mitotic hyperrecombination similiar to that observed in Bloom’s cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6160R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6160R-A350
Lokale Artikelnummer::
BOSSBS-6160R-A350
Beschreibung:
VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.
VE:
1 * 100 µl
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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