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trans-1,4-Cyclohexanedimethanol
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trans-1,4-Cyclohexanedimethanol
Artikel-Nr:
(BOSSBS-15186R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15186R-CY7
Lokale Artikelnummer::
BOSSBS-15186R-CY7
Beschreibung:
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4184R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4184R-A680
Lokale Artikelnummer::
BOSSBS-4184R-A680
Beschreibung:
p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5981R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5981R-FITC
Lokale Artikelnummer::
BOSSBS-5981R-FITC
Beschreibung:
p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5981R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5981R-A680
Lokale Artikelnummer::
BOSSBS-5981R-A680
Beschreibung:
p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11621R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11621R-CY5
Lokale Artikelnummer::
BOSSBS-11621R-CY5
Beschreibung:
The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5981R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5981R-A350
Lokale Artikelnummer::
BOSSBS-5981R-A350
Beschreibung:
p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Lieferant:
VWR Collection
Beschreibung:
Aluminium.
Artikel-Nr:
(NALG2324-0015)
Lieferant:
Thermo Fisher Scientific
Hersteller-Artikelnummer::
2324-0015
Lokale Artikelnummer::
NALG2324-0015
Beschreibung:
Made of PP, translucent.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-2633R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2633R-CY5.5
Lokale Artikelnummer::
BOSSBS-2633R-CY5.5
Beschreibung:
Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury. In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or proinflammatory activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1528R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1528R-CY5.5
Lokale Artikelnummer::
BOSSBS-1528R-CY5.5
Beschreibung:
Attractin is a serum glycoprotein of 175 kDaand found in both membrane-bound and secreted forms as a result of alternative splicing. Both the secreted and membrane-bound forms of attractin may be involved in the development and maintenance of the central nervous system. Membrane-bound attractin is a co-receptor for Agouti, antagonist of melanocortin-1 receptor. Secreted attractin, expressed by activated T lymphocytes and modulates interactions between T cells and monocytes/macrophages, was examined as a potential marker of immune activity. Attractinmay be a component of a pathway for regulated protein turnover that also involves mahogunin, a wide-expressed E3 ubiquitinligase found at particularly high levels in the brain. Attractinwas considered as an extracellular target amenable for the development of obesity-regulating drugs, also.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11621R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11621R-A680
Lokale Artikelnummer::
BOSSBS-11621R-A680
Beschreibung:
The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase Signalling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10 kDa form is found circulating in the blood.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3816R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3816R-CY5.5
Lokale Artikelnummer::
BOSSBS-3816R-CY5.5
Beschreibung:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4039R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4039R-CY5.5
Lokale Artikelnummer::
BOSSBS-4039R-CY5.5
Beschreibung:
SLC37A4 transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. It forms a complex with glucose-6-phosphatase which is responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3816R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3816R-CY5
Lokale Artikelnummer::
BOSSBS-3816R-CY5
Beschreibung:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9246R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9246R-CY5
Lokale Artikelnummer::
BOSSBS-9246R-CY5
Beschreibung:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13572R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13572R
Lokale Artikelnummer::
BOSSBS-13572R
Beschreibung:
The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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