3-(Phenylthio)thiophene
Artikel-Nr:
(BOSSBS-13142R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13142R-A555
Lokale Artikelnummer::
BOSSBS-13142R-A555
Beschreibung:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7348R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7348R-CY7
Lokale Artikelnummer::
BOSSBS-7348R-CY7
Beschreibung:
As a major event in type â… allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcεRIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to FcεRIs on mast cells may inhibit the signal transduction from FcεRIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7348R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7348R-CY5.5
Lokale Artikelnummer::
BOSSBS-7348R-CY5.5
Beschreibung:
As a major event in type â… allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcεRIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to FcεRIs on mast cells may inhibit the signal transduction from FcεRIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI30-432)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-432
Lokale Artikelnummer::
PRSI30-432
Beschreibung:
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase.Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-7348R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7348R-FITC
Lokale Artikelnummer::
BOSSBS-7348R-FITC
Beschreibung:
As a major event in type â… allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcεRIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to FcεRIs on mast cells may inhibit the signal transduction from FcεRIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7348R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7348R-A647
Lokale Artikelnummer::
BOSSBS-7348R-A647
Beschreibung:
As a major event in type â… allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcεRIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to FcεRIs on mast cells may inhibit the signal transduction from FcεRIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4105R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4105R-CY3
Lokale Artikelnummer::
BOSSBS-4105R-CY3
Beschreibung:
Caldesmon, Filamin 1, Nebulin and Villin are differentially expressed and regulated Actin binding proteins. Both muscular (CDh) and non-muscular (CDl) forms of Caldesmon have been identified and each has been shown to bind to Actin as well as to calmodulin and Myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CDl is widely expressed in non-muscle tissues and cells. Filamin 1, which is ubiquitously expressed and exists as a homodimer, functions to crosslink Actin to filaments. Nebulin is a large filamentous protein specific to muscle tissue that may function as a ruler for filament length. Several isoforms of Nebulin are produced by alternative exon usage. Villin is Ca2+-regulated and is the major structural component of the brush border of absorptive cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4105R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4105R-CY5
Lokale Artikelnummer::
BOSSBS-4105R-CY5
Beschreibung:
Caldesmon, Filamin 1, Nebulin and Villin are differentially expressed and regulated Actin binding proteins. Both muscular (CDh) and non-muscular (CDl) forms of Caldesmon have been identified and each has been shown to bind to Actin as well as to calmodulin and Myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CDl is widely expressed in non-muscle tissues and cells. Filamin 1, which is ubiquitously expressed and exists as a homodimer, functions to crosslink Actin to filaments. Nebulin is a large filamentous protein specific to muscle tissue that may function as a ruler for filament length. Several isoforms of Nebulin are produced by alternative exon usage. Villin is Ca2+-regulated and is the major structural component of the brush border of absorptive cells.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Cross linkers are used for the identification of near-neighbour protein relationships and ligand-receptor interactions. Homobifunctional, amine-reactive NHS esters or imidates, and heterobifunctional, amine-reactive, photoactivatable phenyl azides are the most commonly used crosslinkers for these applications.
Lieferant:
FLUOROCHEM
Beschreibung:
1,1'-Carbonyldiimidazol
Artikel-Nr:
(PIER22301)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
22301
Lokale Artikelnummer::
PIER22301
Beschreibung:
Thermo Scientific Pierce PDPH is a short, pyridyldithiol-and-hydrazide crosslinker for reversibly conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).
VE:
1 * 50 mg
Artikel-Nr:
(PIER22610)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
22610
Lokale Artikelnummer::
PIER22610
Beschreibung:
Thermo Scientific Pierce L-Photo-Leucine is an analog of L-leucine that can be incorporated into proteins during synthesis and then light-activated to covalently crosslink interacting proteins in cells.
VE:
1 * 100 mg
Artikel-Nr:
(SIAL803359-50MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
803359-50MG
Lokale Artikelnummer::
SIAL803359-50MG
Beschreibung:
Succinimidyl-diazirine (SDA) reagents are a new class of crosslinkers that combine proven amine-reactive chemistry with an innovative and efficient diazirine-based photochemistry for conjugating amine-containing molecules to nearly any other functional group. The SDA crosslinkers include six compounds differing in spacer arm lengths, ability to cleave the crosslinked proteins, and presence or absence of a charged group for membrane permeability. Protein crosslinking is an important technique used to understand protein structure and to stabilize protein-protein interactions, and these SDA reagents extend the efficiency and range of interactions that can be explored by this approach.
VE:
1 * 50 mg
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Alginic acid is a high molecular weight linear polymer isolated from seaweed. It is a linear β-1→4-linked polymer of n-mannuronic and L-guluronic acid. It is an acid polysaccharide present in the extracellular matrix of brown algae.
Lieferant:
Alfa Aesar
Beschreibung:
MBS (N-Succinimidyl 3-maleimidobenzoate) 95%
Lieferant:
Thermo Scientific
Beschreibung:
Carboxyl groups, in the form of carboxy termini, aspartate residues or glutamate residues, can be targeted for biotin labeling using amine-derivatised biotin molecules. This reaction is mediated by a class of crosslinkers known as carbodiimides and results in the formation of an amide bond. The reaction with EDC, the most common carbodiimide crosslinker, is generally performed in an MES buffer at pH 4,5 to 5 and requires just minutes to complete.
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