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17-DMAG+hydrochloride
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17-DMAG+hydrochloride
Lieferant:
Thermo Scientific
Beschreibung:
(±)-1-Benzyl-3-hydroxypiperidin Hydrochlorid
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Ethoxy-2-fluoranilin Hydrochlorid
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Fluor-4-isopropoxyanilin Hydrochlorid
Artikel-Nr:
(EHERC16707000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C16707000
Lokale Artikelnummer::
EHERC16707000
Beschreibung:
(-)-Chinin Hydrochlorid Dihydrat
VE:
1 * 0,1 g
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Fluor-N-methylanilin Hydrochlorid
Artikel-Nr:
(PRSI33-216)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-216
Lokale Artikelnummer::
PRSI33-216
Beschreibung:
This antibody is specific for a 17-26 kDa protein, which is identified as the cytokine TNF alpha (Tumor Necrosis Factor alpha). It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. It is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. It exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
VE:
1 * 100 µG
New Product
Lieferant:
Sigma-Aldrich
Beschreibung:
2-(Dimethylamino)ethanthiol Hydrochlorid, Sigma-Aldrich®
Lieferant:
CHEMPUR
Beschreibung:
3,4-Dimethoxybenzamidin Hydrochlorid
Artikel-Nr:
(HONCR1329-10MG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
R1329-10MG
Lokale Artikelnummer::
HONCR1329-10MG
Beschreibung:
High quality inorganic and organic reference materials produced according to ISO 9001.
VE:
1 * 10 mg
Artikel-Nr:
(REST24977)
Lieferant:
Restek
Hersteller-Artikelnummer::
24977
Lokale Artikelnummer::
REST24977
Beschreibung:
Inlet liners with deactivation improve trace-level analysis that are suitable for agilent GCs equipped with split/splitless inlets. It is made of borosilicate glass.
VE:
1 * 5 ST
Lieferant:
Thermo Scientific
Beschreibung:
4-Brom-2-ethylanilin Hydrochlorid
Lieferant:
MP Biomedicals
Beschreibung:
D-(+)-Galactosamine hydrochloride is a powerful inhibitor of hepatic RNA synthesis.
Artikel-Nr:
(BOSSBS-1380R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1380R-A647
Lokale Artikelnummer::
BOSSBS-1380R-A647
Beschreibung:
G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilisation and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a RAMP3-dependent manner. Regulates arterial blood pressure by stimulating vasodilation and reducing vascular smooth muscle and microvascular endothelial cell proliferation. Plays a role in blood glucose homeostasis contributing to the insulin secretion response by pancreatic beta cells. Triggers mitochondrial apoptosis during pachytene spermatocyte differentiation. Stimulates uterine epithelial cell proliferation. Enhances uterine contractility in response to oxytocin. Contributes to thymic atrophy by inducing apoptosis. Attenuates TNF-mediated endothelial expression of leukocyte adhesion molecules. Promotes neuritogenesis in developing hippocampal neurons. Plays a role in acute neuroprotection against NMDA-induced excitotoxic neuronal death. Increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons. Inhibits early osteoblast proliferation at growth plate during skeletal development. Inhibits mature adipocyte differentiation and lipid accumulation. Involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells.
VE:
1 * 100 µl
Lieferant:
TCI
Beschreibung:
Adenine hydrochloride hemihydrate, Hemihydrat ≥98,0% (durch titrimetrische Analyse)
Artikel-Nr:
(PRSI26-043)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-043
Lokale Artikelnummer::
PRSI26-043
Beschreibung:
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. PCDH8 is an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.
VE:
1 * 50 µG
Artikel-Nr:
(SIAL270067-100G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
270067-100G
Lokale Artikelnummer::
SIAL270067-100G
Beschreibung:
1-(2-Methoxyphenyl)piperazin Hydrochlorid, Sigma-Aldrich®
VE:
1 * 100 g
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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