To support the ongoing research efforts on Coronavirus SARS-CoV-2 causing COVID-19 disease, we've provided easy access to critical products needed for virus research and detection...
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Avantor ist bereits heute einer der wichtigsten Anbieter von speziellen Färbelösungen für das histologisch pathologische Labor. Wir erweitern täglich unser Produkt-Portfolio für unsere Kunden…
Mit seiner umfassenden Auswahl an Ausstattung für die Mikroskopie ist Avantor zu einem One-Stop-Shop für Kunden geworden, die sowohl spezielle als auch allgemeine Laborausrüstung benötigen.
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Avantor Services provides a wide range of specialized services and digital solutions to help you solve complex challenges.
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You can select and customize services for peak efficiency, quality, and accelerated innovation.
VWR hat eine Reihe von neuen Dienstleistungen entwickelt, mit denen Sie Ihre Abläufe rationalisieren, Kosteneinsparungen erzielen und Ihr Labor effektiv führen...
Beschreibung:
High purity solvents for speciation analysis by LC-ICP-MS. Rigorous purification procedures followed by UV spectroscopy, IC, and ICP-MS testing to assure high chemical purity and high UV transmittance. The blank values for metal traces in these solvents are in the ppb range or lower.
Beschreibung:
Thermo Scientific Pierce Sulfo-SMCC, No-Weigh Format is a water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 angstroms).
Beschreibung:
Thermo Scientific Pierce Premium Grade Sulfo-SMCC is our highest quality formulation of amine-to-sulfhydryl crosslinker, specially characterized for applications where product integrity and risk minimization are paramount.
Beschreibung:
Voltage-tunable multicolor emission with enhanced luminance (~1000 cd/m²) was observed using varying amounts of DCM dye in a polymer light-emitting diode (PLED)
Beschreibung:
GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency, which is an autosomal recessive disorder characterised by developmental delay/regression, mental retardation, severe disturbance of expressive and cognitive speech, intractable seizures and movement disturbances, severe depletion of creatine/phosphocreatine in the brain, and accumulation of guanidinoacetic acid in brain and body fluids.
Beschreibung:
Phospholipase A2(PLA2G1B) is a secreted protein which belongs to the phospholipase A2 family. It catalyses the release of fatty acids from glycero-3-phosphocholines. It catalyses the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Sequences of pancreatic PLA2G1B enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Mice lacking in PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet. Oral supplementation of a diabetogenic diet with the PLA2G1B inhibitor methyl indoxam effectively suppresses diet-induced obesity and diabetes. PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes.
Beschreibung:
Storage: Room Temperature, desiccate, store under nitrogen. Dimethyl Sulfoxide is a dipola, aprotic solvent. It has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination. Dimethyl Sulfoxide is used to enhance dermal absorption of many chemicals, as a solvent for many organic and inorganic compounds including fats, carbohydrates, dyes, resins, and polymers, in antifreeze or hydraulic fluids, as a cryopreservative for cell cultures, oxidation of thiols and disulfides to sulfonic acids, as a PCR cosolvent to help improve yields, especially in long PCR. DMSO is routinely used in polymerase chan reaction (PCR), amplification of cDNA libraries, DNA sequencing, column-loading buffers for poly (A)+ RNA selection, buffers for the transformation of competent E. coli, and transfection protocols. To prepare sterile solutions use a teflon or nylon membrane to sterile-filter the DMSO - do not use a cellulose acetate membrane.
Beschreibung:
Adenosine 5'-triphosphate (ATP) disodium salt hydrate is a multifunctional nucleotide, which is essential in a variety of cellular functions.
Beschreibung:
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003; Seidenman et al., 2003; Chung et al., 2003; Yan et al., 2002).
Beschreibung:
Creatinine, the end product of creatine catabolism is a normal constituent of urine; daily output about 25 mg/kg body weight. The increased amounts in the urine are typically associated with substantially impaired renal function. Also found together with creatine in muscle tissues and blood. It reacts with picric acid under alkaline conditions to form a Janovski complex. The rate of formation of the colored complex, measured at 480-520 nm is proportional to the creatinine concentration. Creatinine is a useful marker for normalizing levels of other molecules found in urine and the altered creatinine levels may be associated with conditions that result in decreased renal blood flow, such as diabetes and cardiovascular disease.
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