Methyl+2-chloro-6-(trifluoromethyl)isonicotinate
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Artikel-Nr:
(BC07)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
BC07
Lokale Artikelnummer::
GENOBC07
Beschreibung:
Dithiobis(succinimidyl propionate) Homobifunctional Cross Linker.
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Primary amine reactive -Hydroxylamine CleavableCrosslink receptor ligand complexes.
Artikel-Nr:
(BOSSBS-7674R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7674R-CY3
Lokale Artikelnummer::
BOSSBS-7674R-CY3
Beschreibung:
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
DSS (Disuccinimidylsuberat) 97%
Artikel-Nr:
(BOSSBS-7348R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7348R-CY3
Lokale Artikelnummer::
BOSSBS-7348R-CY3
Beschreibung:
As a major event in type â… allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcεRIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to FcεRIs on mast cells may inhibit the signal transduction from FcεRIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15492R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15492R
Lokale Artikelnummer::
BOSSBS-15492R
Beschreibung:
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Lieferant:
MACHEREY-NAGEL
Beschreibung:
Cyclodextrin modified silica phases for HPLC enantiomer separation. These phases are especially suited for the control of optical purity and for the analysis of positional and cis-trans isomers.
Artikel-Nr:
(BSBTPB9091)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PB9091
Lokale Artikelnummer::
BSBTPB9091
Beschreibung:
Polyclonal antibody for APP detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. APP information: Molecular Weight: 86943 MW; Subcellular Localization: Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit. Cell surface protein that rapidly becomes internalized via clathrin-coated pits. During maturation, the immature APP (N-glycosylated in the endoplasmic reticulum) moves to the Golgi complex where complete maturation occurs (O-glycosylated and sulfated). After alpha-secretase cleavage, soluble APP is released into the extracellular space and the C-terminal is internalized to endosomes and lysosomes. Some APP accumulates in secretory transport vesicles leaving the late Golgi compartment and returns to the cell surface. Gamma-CTF(59) peptide is located to both the cytoplasm and nuclei of neurons. It can be translocated to the nucleus through association with APBB1 (Fe65). Beta-APP42 associates with FRPL1 at the cell surface and the complex is then rapidly internalized. APP sorts to the basolateral surface in epithelial cells. During neuronal differentiation, the Thr-743 phosphorylated form is located mainly in growth cones, moderately in neurites and sparingly in the cell body. Casein kinase phosphorylation can occur either at the cell surface or within a post-Golgi compartment. Associates with GPC1 in perinuclear compartments. Colocalizes with SORL1 in a vesicular pattern in cytoplasm and perinuclear regions; Tissue Specificity: Expressed in all fetal tissues examined with highest levels in brain, kidney, heart and spleen. Weak expression in liver. In adult brain, highest expression found in the frontal lobe of the cortex and in the anterior perisylvian cortex- opercular gyri. Moderate expression in the cerebellar cortex, the posterior perisylvian cortex-opercular gyri and the temporal associated cortex. Weak expression found in the striate, extra- striate and motor cortices. Expressed in cerebrospinal fluid, and plasma. Isoform APP695 is the predominant form in neuronal tissue, isoform APP751 and isoform APP770 are widely expressed in non- neuronal cells. Isoform APP751 is the most abundant form in T- lymphocytes. Appican is expressed in astrocytes.
VE:
1 * 100 µG
Artikel-Nr:
(IMMRIR2937)
Lieferant:
ImmunoReagents
Hersteller-Artikelnummer::
IR2937
Lokale Artikelnummer::
IMMRIR2937
Beschreibung:
The ImmunoReagents' Allophycocyanin (APC) is an intensely bright phycobiliprotein isolated from red algae that exhibits far-red fluorescence with high quantum yields. It is excited by laser lines at 594 and 633 nm, with an absorbance maximum at 650 nm and a fluorescence emission peak at 660 nm. APC is a large molecule that is chemically crosslinked to use in fluorescence-based detection, primarily for flow cytometry, microarray assays, ELISAs, and other applications that require high sensitivity but not photostability.
VE:
1 * 0,5 mL
Artikel-Nr:
(BOSSBS-7674R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7674R-CY5
Lokale Artikelnummer::
BOSSBS-7674R-CY5
Beschreibung:
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1580R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1580R
Lokale Artikelnummer::
BOSSBS-1580R
Beschreibung:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group F. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(ACRO398681000)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
398681000
Lokale Artikelnummer::
ACRO398681000
Beschreibung:
GMBS (N-Succinimidyl 4-maleimidobutyrate) 97%
VE:
1 * 100 mg
Artikel-Nr:
(BOSSBS-13142R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13142R-FITC
Lokale Artikelnummer::
BOSSBS-13142R-FITC
Beschreibung:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7348R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7348R-A680
Lokale Artikelnummer::
BOSSBS-7348R-A680
Beschreibung:
As a major event in type allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcRIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to FcRIs on mast cells may inhibit the signal transduction from FcRIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Sulphhydryl reactive -Carbohydrate reactive
Artikel-Nr:
(BOSSBS-7348R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7348R-A488
Lokale Artikelnummer::
BOSSBS-7348R-A488
Beschreibung:
As a major event in type â… allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (FcεRIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to FcεRIs on mast cells may inhibit the signal transduction from FcεRIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.
VE:
1 * 100 µl
Preis auf Anfrage
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