Potassium+trifluoro(3-oxocyclopentyl)borate
Artikel-Nr:
(BOSSBS-10178R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10178R-FITC
Lokale Artikelnummer::
BOSSBS-10178R-FITC
Beschreibung:
The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0582R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0582R-HRP
Lokale Artikelnummer::
BOSSBS-0582R-HRP
Beschreibung:
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1051R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1051R-A350
Lokale Artikelnummer::
BOSSBS-1051R-A350
Beschreibung:
Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is involved in adhesive interactions of leukocytes. It is a receptor for fibronectin and recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Integrin alpha-4/beta-7 is also a receptor for MADCAM1 and VCAM1. It recognizes the sequence L-D-T in MADCAM1. Integrin alpha-E/beta-7 is a receptor for E-cadherin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4593R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4593R-A555
Lokale Artikelnummer::
BOSSBS-4593R-A555
Beschreibung:
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1051R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1051R-A680
Lokale Artikelnummer::
BOSSBS-1051R-A680
Beschreibung:
Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is involved in adhesive interactions of leukocytes. It is a receptor for fibronectin and recognises one or more domains within the alternatively spliced CS-1 region of fibronectin. Integrin alpha-4/beta-7 is also a receptor for MADCAM1 and VCAM1. It recognises the sequence L-D-T in MADCAM1. Integrin alpha-E/beta-7 is a receptor for E-cadherin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0397R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0397R-CY3
Lokale Artikelnummer::
BOSSBS-0397R-CY3
Beschreibung:
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2032R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2032R-A350
Lokale Artikelnummer::
BOSSBS-2032R-A350
Beschreibung:
PMP2 is a small basic protein, belonging to the fatty-acid binding protein (FABP) family and is one of the major proteins of peripheral myelin. It appears to be involved in the transport of fatty acids or the metabolism of myelin lipids, and has been shown to have lipid-binding activity. PMP2 protein may have an important role in the organization of compact myelin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7731R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7731R-CY7
Lokale Artikelnummer::
BOSSBS-7731R-CY7
Beschreibung:
Human SUG1 (also known as p45, Rpt6, Cim3 and PSMC5) is a component of the 19S regulatory subunit of the 26S proteosome complex. It is one of the AAA ATPas found in the 19S regulatory complex that is thought to participate in the unfolding of ubiquitinated proteins in an ATP dependent manner. It has also been shown to directly interact with the nucleotide excision repair protein XPB.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V; Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.
Artikel-Nr:
(BOSSBS-11983R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11983R-A488
Lokale Artikelnummer::
BOSSBS-11983R-A488
Beschreibung:
Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an Alpha1 subunit, a Beta subunit, a Beta subunit and an Alpha2 Gamma subunit. The Beta subunit is encoded by four genes, designated Beta1-Beta 4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the Beta subunit. L-type Ca++ CP Beta 4, also known as CACNB4 (Calcium channel voltage-dependent subunit beta 4), CACNLB4 or CAB4, is a 484 amino acid protein that contains one SH3 domain and is expressed in ovary, brain and smooth muscle. Functioning as one of the four components of the Beta subunit, L-type Ca++ CP Beta 4 increases the peak calcium current in voltage-dependent calcium channels, thereby shifting the voltage dependencies of activation and inactivation and controlling G protein inhibition and Beta membrane targeting. Two isoforms of L-type Ca++ CP Beta4 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13726R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13726R-A555
Lokale Artikelnummer::
BOSSBS-13726R-A555
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.
VE:
1 * 100 µl
Lieferant:
Tonbo Biosciences
Beschreibung:
The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB, CD45RO and several others. The RA3-6B2 antibody is one of the most consistently used leukocyte markers for B cells, T cell subsets and NK cell subsets in human and mouse. This antibody has also been reported as cross-reactive with feline CD45R/B220.
Artikel-Nr:
(BOSSBS-5745R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5745R-A680
Lokale Artikelnummer::
BOSSBS-5745R-A680
Beschreibung:
CKS1 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5745R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5745R-CY3
Lokale Artikelnummer::
BOSSBS-5745R-CY3
Beschreibung:
CKS1 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5714R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5714R-CY5.5
Lokale Artikelnummer::
BOSSBS-5714R-CY5.5
Beschreibung:
OVCA1 is required for the first step in the synthesis of diphthamide, a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. OVCA1 is one of several enzymes involved in synthesis of diphthamide in EEF2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8021R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8021R-CY5
Lokale Artikelnummer::
BOSSBS-8021R-CY5
Beschreibung:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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