SCHERF PRAZISION
Lieferant:
Thermo Scientific
Beschreibung:
Methylenblau Hydrat 96+%, hochrein biologische Färbemittel
Artikel-Nr:
(23257.183)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC23257.183
Beschreibung:
L(+)-Cystein Hydrochlorid Monohydrat 98,5-101,0% für die Biochemie
VE:
1 * 100 g
Artikel-Nr:
(BOSSBS-8333R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-A750
Lokale Artikelnummer::
BOSSBS-8333R-A750
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localises on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognises retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8333R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-HRP
Lokale Artikelnummer::
BOSSBS-8333R-HRP
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
(3S)-(-)-cis-3,6-Dimethyl-1,4-dioxan-2,5-dion, Sigma-Aldrich®
Artikel-Nr:
(AGRIAS09431)
Lieferant:
Agrisera
Hersteller-Artikelnummer::
AS09431
Lokale Artikelnummer::
AGRIAS09431
Beschreibung:
Anti-cis-zeatin riboside Rabbit Polyclonal Antibody
VE:
1 * 200 µG
Artikel-Nr:
(BOSSBS-11269R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11269R
Lokale Artikelnummer::
BOSSBS-11269R
Beschreibung:
The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin (1). Several related immunophilins, FKBP12, FKBP51 and FKBP52, are characterized as cytosolic FK506-binding proteins, and following ligand binding, they functionally inhibit the phosphatase activity of calcineurin (2,3). The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGF?type I receptor, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGF?pathway (4). FKBP51 and FKBP52 are two highly related proteins (5,6). FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids (5). FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, and by blocking T-cell activation and proliferation (7). FKBP52, known also as FKBP-59 or heat shock protein 56, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6,8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3541R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3541R-A488
Lokale Artikelnummer::
BOSSBS-3541R-A488
Beschreibung:
Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
1,4-Bis(hydroxymethyl)cyclohexan (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Ethyl-3-phenylglycidat (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
Artikel-Nr:
(USBI040321-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040321-BIOTIN
Lokale Artikelnummer::
USBI040321-BIOTIN
Beschreibung:
Anti-PPIL6 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(SIALW372005-25G-K)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
W372005-25G-K
Lokale Artikelnummer::
SIALW372005-25G-K
Beschreibung:
(2Z)-2-Nonen-1-ol, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-12287R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12287R-A350
Lokale Artikelnummer::
BOSSBS-12287R-A350
Beschreibung:
Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules; and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12287R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12287R-A555
Lokale Artikelnummer::
BOSSBS-12287R-A555
Beschreibung:
Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules; and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3541R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3541R-HRP
Lokale Artikelnummer::
BOSSBS-3541R-HRP
Beschreibung:
Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
VE:
1 * 100 µl
Artikel-Nr:
(HEWL5062-3525)
Lieferant:
Agilent
Hersteller-Artikelnummer::
5062-3525
Lokale Artikelnummer::
HEWL5062-3525
Beschreibung:
Graphpak nut for CIS
VE:
1 * 5 ST
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||