1-Butyl-3-methylimidazolium+hydrogen+sulphate
Artikel-Nr:
(BOSSBS-7653R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7653R-A647
Lokale Artikelnummer::
BOSSBS-7653R-A647
Beschreibung:
Has DNA hydrolytic activity. Does not bind to actin. Cleaves chromatin DNA to nucleosomal units.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5819R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5819R-A350
Lokale Artikelnummer::
BOSSBS-5819R-A350
Beschreibung:
AROS-29 is suggested to have a functional role in protection against oxidative stress. The gene encoding AROS-29 is located on human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7934R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7934R-A647
Lokale Artikelnummer::
BOSSBS-7934R-A647
Beschreibung:
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6184R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6184R-A555
Lokale Artikelnummer::
BOSSBS-6184R-A555
Beschreibung:
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6748R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6748R-A488
Lokale Artikelnummer::
BOSSBS-6748R-A488
Beschreibung:
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studied as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6900R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6900R-CY5.5
Lokale Artikelnummer::
BOSSBS-6900R-CY5.5
Beschreibung:
Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11878R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11878R
Lokale Artikelnummer::
BOSSBS-11878R
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system, LRRTM family members are known to exhibit synaptogenic activity. LRRTM4 (leucine-rich repeat transmembrane neuronal protein 4) is a 590 amino acid member of the LRRTM protein family. Expressed in neuronal tissues, LRRTM4 may play a role in the development and maintenance of the vertebrate nervous system. A single-pass type I membrane protein, LRRTM4 contains 10 LRR repeats. LRRTM4 is expressed as two isoforms produced by alternative splicing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6834R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6834R-CY7
Lokale Artikelnummer::
BOSSBS-6834R-CY7
Beschreibung:
This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6909R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6909R-CY3
Lokale Artikelnummer::
BOSSBS-6909R-CY3
Beschreibung:
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6851R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6851R-CY3
Lokale Artikelnummer::
BOSSBS-6851R-CY3
Beschreibung:
The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3364R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3364R-A555
Lokale Artikelnummer::
BOSSBS-3364R-A555
Beschreibung:
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes. In response to mitogenic stimulation (EGF and PMA), phosphorylates and activates NR4A1/NUR77 and ETV1/ER81 transcription factors and the cofactor CREBBP. Upon insulin-derived signal, acts indirectly on the transcription regulation of several genes by phosphorylating GSK3B at 'Ser-9' and inhibiting its activity. Phosphorylates RPS6 in response to serum or EGF via an mTOR-independent mechanism and promotes translation initiation by facilitating assembly of the preinitiation complex. In response to insulin, phosphorylates EIF4B, enhancing EIF4B affinity for the EIF3 complex and stimulating cap-dependent translation. Is involved in the mTOR nutrient-sensing pathway by directly phosphorylating TSC2 at 'Ser-1798', which potently inhibits TSC2 ability to suppress mTOR signaling, and mediates phosphorylation of RPTOR, which regulates mTORC1 activity and may promote rapamycin-sensitive signaling independently of the PI3K/AKT pathway. Mediates cell survival by phosphorylating the pro-apoptotic proteins BAD and DAPK1 and suppressing their pro-apoptotic function. Promotes the survival of hepatic stellate cells by phosphorylating CEBPB in response to the hepatotoxin carbon tetrachloride (CCl4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1966R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1966R
Lokale Artikelnummer::
BOSSBS-1966R
Beschreibung:
Anti-KLK7 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12551R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12551R-CY7
Lokale Artikelnummer::
BOSSBS-12551R-CY7
Beschreibung:
Mahogany (MG), originally identified as a protein involved in pigmentation, acts in conjunction with melanocortin receptors to suppress diet-induced obesity. Mahogany contains a single transmembrane domain, and it is expressed in a broad range of tissues, including the hypothalamus and pigment cells. Mutations within the mahogany gene were shown to rescue agouti-lethal-yellow mutant mice from obesity. The extracellular domain of mouse mahogany is the ortholog of the human protein attractin. Attractin (also designated DPPT-L) is a human serum glycoprotein and is a member of the CUB family of cell adhesion and guidance proteins. Attractin is expressed on activated T cells and is released from the cells 48 to 72 hours after activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3893R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3893R-A555
Lokale Artikelnummer::
BOSSBS-3893R-A555
Beschreibung:
May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nuceleolar architecture is observed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0265R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0265R
Lokale Artikelnummer::
BOSSBS-0265R
Beschreibung:
Anti-CKLFSF2 isoform 1 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1682R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1682R-CY5
Lokale Artikelnummer::
BOSSBS-1682R-CY5
Beschreibung:
CIB1(Calcium and integrin binding 1) may convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through the binding to the integrin cytoplasmic domain.
VE:
1 * 100 µl
Preis auf Anfrage
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