3,4,5-Trimethoxybenzhydrazid
Lieferant:
Brand
Beschreibung:
Borosilikatglas 3.3.
Lieferant:
LAMAPLAST
Beschreibung:
LDPE, durchscheinend oder grau.
Artikel-Nr:
(494461-5)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
494461-5
Lokale Artikelnummer::
CALB494461-5
Beschreibung:
Octyl-β-D-thioglucopyranosid, Calbiochem®
VE:
1 * 5 g
Lieferant:
Thermo Scientific
Beschreibung:
5-Fluorsalicylsäure
Artikel-Nr:
(BURK2601-2020)
Lieferant:
BURKLE
Hersteller-Artikelnummer::
2601-2020
Lokale Artikelnummer::
BURK2601-2020
Beschreibung:
Platzsparender Sicherheitsbehälter, rostfreier Edelstahl, mit Schraubverschluss, Überdruckventil und PTFE-Dichtungen für Lagerung.
VE:
1 * 1 ST
Lieferant:
Alfa Aesar
Beschreibung:
Palatinose hydrate ≥98%
Artikel-Nr:
(BOSSBS-6417R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6417R-A750
Lokale Artikelnummer::
BOSSBS-6417R-A750
Beschreibung:
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Involved in the activation of AKT1 upon stimulation by G-protein coupled receptors (GPCRs) ligands such as CXCL12, sphingosine 1-phosphate, and lysophosphatidic acid. May also act downstream receptor tyrosine kinases. Required in different signaling pathways for stable platelet adhesion and aggregation. Plays a role in platelet activation signaling triggered by GPCRs, alpha-IIb/beta-3 integrins (ITGA2B/ ITGB3) and ITAM (immunoreceptor tyrosine-based activation motif)-bearing receptors such as GP6. Regulates the strength of adhesion of ITGA2B/ ITGB3 activated receptors necessary for the cellular transmission of contractile forces. Required for platelet aggregation induced by F2 (thrombin) and thromboxane A2 (TXA2). Has a role in cell survival. May have a role in cell migration. Involved in the early stage of autophagosome formation. Modulates the intracellular level of PtdIns3P (Phosphatidylinositol 3-phosphate) and activates PIK3C3 kinase activity. May act as a scaffold, independently of its lipid kinase activity to positively regulate autophagy. May have a role in insulin signaling as scaffolding protein in which the lipid kinase activity is not required. May have a kinase-independent function in regulating cell proliferation and in clathrin-mediated endocytosis. Mediator of oncogenic signal in cell lines lacking PTEN. The lipid kinase activity is necessary for its role in oncogenic transformation. Required for the growth of ERBB2 and RAS driven tumors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10656R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10656R-A488
Lokale Artikelnummer::
BOSSBS-10656R-A488
Beschreibung:
Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Mediates immune responses. Plays a role in B-cell development, proliferation, migration, and function. Required for B-cell receptor (BCR) signaling. Mediates B-cell proliferation response to anti-IgM, anti-CD40 and IL4 stimulation. Promotes cytokine production in response to TLR4 and TLR9. Required for antibody class switch mediated by TLR9. Involved in the antigen presentation function of B-cells. Involved in B-cell chemotaxis in response to CXCL13 and sphingosine 1-phosphate (S1P). Required for proliferation, signaling and cytokine production of naive, effector and memory T-cells. Required for T-cell receptor (TCR) signaling. Mediates TCR signaling events at the immune synapse. Activation by TCR leads to antigen-dependent memory T-cell migration and retention to antigenic tissues. Together with PIK3CG participates in T-cell development. Contributes to T-helper cell expansion and differentiation. Required for T-cell migration mediated by homing receptors SELL/CD62L, CCR7 and S1PR1 and antigen dependent recruitment of T-cells. Together with PIK3CG is involved in natural killer (NK) cell development and migration towards the sites of inflammation. Participates in NK cell receptor activation. Have a role in NK cell maturation and cytokine production. Together with PIK3CG is involved in neutrophil chemotaxis and extravasation. Together with PIK3CG participates in neutrophil respiratory burst. Have important roles in mast-cell development and mast cell mediated allergic response. Involved in stem cell factor (SCF)-mediated proliferation, adhesion and migration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5587R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5587R-A350
Lokale Artikelnummer::
BOSSBS-5587R-A350
Beschreibung:
Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Mediates immune responses. Plays a role in B-cell development, proliferation, migration, and function. Required for B-cell receptor (BCR) signaling. Mediates B-cell proliferation response to anti-IgM, anti-CD40 and IL4 stimulation. Promotes cytokine production in response to TLR4 and TLR9. Required for antibody class switch mediated by TLR9. Involved in the antigen presentation function of B-cells. Involved in B-cell chemotaxis in response to CXCL13 and sphingosine 1-phosphate (S1P). Required for proliferation, signaling and cytokine production of naive, effector and memory T-cells. Required for T-cell receptor (TCR) signaling. Mediates TCR signaling events at the immune synapse. Activation by TCR leads to antigen-dependent memory T-cell migration and retention to antigenic tissues. Together with PIK3CG participates in T-cell development. Contributes to T-helper cell expansion and differentiation. Required for T-cell migration mediated by homing receptors SELL/CD62L, CCR7 and S1PR1 and antigen dependent recruitment of T-cells. Together with PIK3CG is involved in natural killer (NK) cell development and migration towards the sites of inflammation. Participates in NK cell receptor activation. Have a role in NK cell maturation and cytokine production. Together with PIK3CG is involved in neutrophil chemotaxis and extravasation. Together with PIK3CG participates in neutrophil respiratory burst. Have important roles in mast-cell development and mast cell mediated allergic response. Involved in stem cell factor (SCF)-mediated proliferation, adhesion and migration.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
(2-Nitrophenyl)-β-D-galactopyranosid (ONPG), Sigma-Aldrich®
Artikel-Nr:
(MOLEM14809891)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M14809891
Lokale Artikelnummer::
MOLEM14809891
Beschreibung:
Hesperidin
VE:
1 * 100 g
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Artikel-Nr:
(PIER34055)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
34055
Lokale Artikelnummer::
PIER34055
Beschreibung:
(2-Nitrophenyl)-β-D-galactopyranosid (ONPG)
VE:
1 * 5 g
Lieferant:
Alfa Aesar
Beschreibung:
Myricetin 98%
Artikel-Nr:
(MOLEM42887890)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M42887890
Lokale Artikelnummer::
MOLEM42887890
Beschreibung:
(4-Nitrophenyl)-α-D-galactopyranosid
VE:
1 * 1 g
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