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3,5-Dioxocyclohexanecarboxylic acid
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3,5-Dioxocyclohexanecarboxylic acid
Artikel-Nr:
(PRSI77-061)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-061
Lokale Artikelnummer::
PRSI77-061
Beschreibung:
The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen.The 11B11 antibody neutralizes the IL-4 cytokine.
VE:
1 * 0,1 mg
New Product
Lieferant:
Honeywell Chemicals
Beschreibung:
Bariumacetat ≥99%, Puriss. p.a. ACS, Fluka™
Artikel-Nr:
(PRSI77-012)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-012
Lokale Artikelnummer::
PRSI77-012
Beschreibung:
The LN3 monoclonal antibody specifically reacts with the human leukocyte antigen-DR (HLA-DR), a MHC class II heterodimeric surface glycoprotein. HLA-DR is expressed on the antigen presenting surfaces of monocytes, macrophages, dendritic cells, activated T cells, and B cells. It is integral to peptide presentation to CD4+ T cells.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(PRSI92-004)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-004
Lokale Artikelnummer::
PRSI92-004
Beschreibung:
Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus, a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose, which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II, an autosomal recessive deficiency characterised by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of Galactitol in the lenses.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-894)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-894
Lokale Artikelnummer::
PRSI33-894
Beschreibung:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). Cytokeratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibody that recognises only cytokeratin 8 and 18. Cytokeratin 8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI33-276)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-276
Lokale Artikelnummer::
PRSI33-276
Beschreibung:
CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI91-720)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-720
Lokale Artikelnummer::
PRSI91-720
Beschreibung:
Apolipoprotein A4 (APOA4) is a secreted protein that belongs to the apolipoprotein A1/A4/E family. Apoa-IV is a major component of HDL and chylomicrons. APOA4 is secreted into circulation on the surface of newly synthesized chylomicron particles. APOA4 play a role in the regulation of appetite and satiety in rodent models. APOA4 involved in chylomicrons and VLDL secretion and catabolism and required for efficient activation of lipoprotein lipase by ApoC-II. In addition, APOA4 is a potent activator of lecithin-cholesterol acyltransferase in vitro.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-594)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-594
Lokale Artikelnummer::
PRSI26-594
Beschreibung:
Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF3 is required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-034)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-034
Lokale Artikelnummer::
PRSI28-034
Beschreibung:
BRD2 is a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human gene may be part of a signal transduction pathway involved in growth control.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-856)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-856
Lokale Artikelnummer::
PRSI27-856
Beschreibung:
The protein encoded by TCEA2 is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI76-749)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-749
Lokale Artikelnummer::
PRSI76-749
Beschreibung:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45 kDa type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
VE:
1 * 25 Tests
New Product
Artikel-Nr:
(PRSI91-131)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-131
Lokale Artikelnummer::
PRSI91-131
Beschreibung:
beta -Lactamase-like Protein 2 (LACTB2) is a number of the metallo-beta-lactamase superfamily.LACTB2 also belongs to the Glyoxalase II family. LACTB2 is 288 amino acids long with 8 zinc-binding domains. The LACTB2 gene is expressed at high levels and annotates structural defects or features in 4 cDNA clones. LACTB2 proteins are expected to have hydrolase activity and metal ion-binding functions. LACTB2 protein is found to localize in mitochondrion. Other functions of LACTB2 is yet unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-225)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-225
Lokale Artikelnummer::
PRSI30-225
Beschreibung:
CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI30-351)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-351
Lokale Artikelnummer::
PRSI30-351
Beschreibung:
IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B.The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI36-354)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-354
Lokale Artikelnummer::
PRSI36-354
Beschreibung:
Profilin (PFN1) is a ubiquitous small (12-15kDa) phosphoinositide and poly-L-proline binding protein that plays a role in signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties. Whereas profilin I appears to be highly expressed in most tissues except for skeletal muscle, profilin II is predominantly expressed in brain and at lower levels also in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes. Profilin binding to PIP2 interferes with PIP2 hydrolysis by soluble phospholipase C-gamma, an inhibition that can be overcome by tyrosine phosphorylation of PLC-gamma. Besides actin monomer sequestration and stimulation of actin nucleotide exchange, profilin can also promote cellular actin filament growth. Profilin is involved in the actin dependent intracellular motility of cytopathogenic bacteria, the regulation of cell adhesion and possibly also in linking the actin cytoskeleton and endocytosis. Profilin has been found to associate with defined complexes containing proteins such as Arp2/3 or the Rho/Rac pathways constituents ROCK-II and HEM2/NAP1. Defects in PFN1 are the cause of amyotrophic lateral sclerosis 18 (ALS18).
VE:
1 * 10 µG
Artikel-Nr:
(STRE44-6200-1G)
Lieferant:
Strem Chemicals, Inc.
Hersteller-Artikelnummer::
44-6200-1G
Lokale Artikelnummer::
STRE44-6200-1G
Beschreibung:
Metallocenes, Derivatives & Cp Precursors, Volatile Organometallics for CVD & ALD, Volatile Precursors for CVD
VE:
1 * 1 g
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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