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Artikel-Nr:
(BOSSBS-13028R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13028R-CY3
Lokale Artikelnummer::
BOSSBS-13028R-CY3
Beschreibung:
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP10 (dipeptidyl-peptidase 10), also known as DPRP3 (dipeptidyl peptidase IV-related protein 3), DPL2 or DPPY, is a non-functional dipeptidyl peptidase which can bind to the potassium channels KV4.1 and KV4.2. It is a single-pass type II membrane protein expressed in spinal cord, adrenal glands, pancreas and brain tissues and may act as a modulator for cell surface expression and activity of KV4.1 and KV4.2.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
Ammoniumheptamolybdat Tetrahydrat ACS, ISO, Reag. Ph. Eur. analytisches Reagens, Supelco®
Artikel-Nr:
(BOSSBS-6216R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6216R-CY5
Lokale Artikelnummer::
BOSSBS-6216R-CY5
Beschreibung:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13028R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13028R-A555
Lokale Artikelnummer::
BOSSBS-13028R-A555
Beschreibung:
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP10 (dipeptidyl-peptidase 10), also known as DPRP3 (dipeptidyl peptidase IV-related protein 3), DPL2 or DPPY, is a non-functional dipeptidyl peptidase which can bind to the potassium channels KV4.1 and KV4.2. It is a single-pass type II membrane protein expressed in spinal cord, adrenal glands, pancreas and brain tissues and may act as a modulator for cell surface expression and activity of KV4.1 and KV4.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13028R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13028R-A680
Lokale Artikelnummer::
BOSSBS-13028R-A680
Beschreibung:
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP10 (dipeptidyl-peptidase 10), also known as DPRP3 (dipeptidyl peptidase IV-related protein 3), DPL2 or DPPY, is a non-functional dipeptidyl peptidase which can bind to the potassium channels KV4.1 and KV4.2. It is a single-pass type II membrane protein expressed in spinal cord, adrenal glands, pancreas and brain tissues and may act as a modulator for cell surface expression and activity of KV4.1 and KV4.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6216R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6216R
Lokale Artikelnummer::
BOSSBS-6216R
Beschreibung:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of α, β, and γ chains. This MAb reacts with laminin B2/1 chain of ~210 kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.
Lieferant:
Biotium
Beschreibung:
Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of α, β, and γ chains. This MAb reacts with laminin B2/1 chain of ~210 kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.
Artikel-Nr:
(SIAL666610-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
666610-25G
Lokale Artikelnummer::
SIAL666610-25G
Beschreibung:
Hafniumtetrakis(dimethylazanid), Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(SIAL455199-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
455199-25G
Lokale Artikelnummer::
SIAL455199-25G
Beschreibung:
Hafniumtetrakis(dimethylazanid), Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(BSENM-1378-250)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1378-250
Lokale Artikelnummer::
BSENM-1378-250
Beschreibung:
Neurofilaments can be defined as the intermediate or 10nm diameter filaments found in neuronal cells. They are composed a mixture of subunits which often includes the neurofilament triplet proteins, NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Alpha-internexin is a ~66 kDa Class IV intermediate filament subunit expressed in large amounts early in neuronal development, but is downregulated in many neurons as development procedes. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to alpha-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of alpha-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage.
VE:
1 * 250 µl
Artikel-Nr:
(SIALP7082-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
P7082-1G
Lokale Artikelnummer::
SIALP7082-1G
Beschreibung:
Hexachloroplatinsäure Hexahydrat
VE:
1 * 1 g
Artikel-Nr:
(USBI038195)
Lieferant:
US Biological
Hersteller-Artikelnummer::
038195
Lokale Artikelnummer::
USBI038195
Beschreibung:
Anti-MARCH4 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBI126743)
Lieferant:
US Biological
Hersteller-Artikelnummer::
126743
Lokale Artikelnummer::
USBI126743
Beschreibung:
Anti-FEN1 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(SIAL224316-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
224316-5G
Lokale Artikelnummer::
SIAL224316-5G
Beschreibung:
Zirkonylchlorid Octahydrat 98%, Reagenzqualität, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-11296R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11296R-A750
Lokale Artikelnummer::
BOSSBS-11296R-A750
Beschreibung:
17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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