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3-((tert-Butoxycarbonyl)amino)-2-hydroxypropanoic+acid
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3-((tert-Butoxycarbonyl)amino)-2-hydroxypropanoic+acid
Artikel-Nr:
(BOSSBS-13232R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13232R
Lokale Artikelnummer::
BOSSBS-13232R
Beschreibung:
FUZ is a 418 amino acid protein that localizes to both the cytoskeleton and the cytoplasm and is a human homolog of the Drosophila fuzzy protein. Existing as three alternatively spliced isoforms, FUZ is thought to be involved in regulating cytoskeletal function and may also play a role in maintaining cell polarity in epithelial cells. The gene encoding FUZ maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, several ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11581R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11581R-CY3
Lokale Artikelnummer::
BOSSBS-11581R-CY3
Beschreibung:
PDZ-GEF1 is a 1,499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8293R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8293R-CY5
Lokale Artikelnummer::
BOSSBS-8293R-CY5
Beschreibung:
DQX1 (DEAQ box RNA-dependent ATPase 1), also known as FLJ23757, is a 71 amino acid protein that contains one helicase ATP-binding domain and one helicase C-terminal domain. Localized to the nucleus, DQX1 catalyzes the conversion of ATP to ADP and a phosphate. Expressed as three isoforms produced by alternative splicing events, DQX1 is encoded by a gene that maps to human chomosome 2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstré°‰ syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13152R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13152R-A680
Lokale Artikelnummer::
BOSSBS-13152R-A680
Beschreibung:
FCHO1 (FCH domain only 1) is an 889 amino acid protein that contains one FCH domain and exists as multiple alternatively spliced isoforms. The gene encoding FCHO1 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8718R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8718R-A488
Lokale Artikelnummer::
BOSSBS-8718R-A488
Beschreibung:
RSAD2 is a 361 amino acid protein that is involved in antiviral defense against pathogens such as Hep C, Cytomegalovirus and HIV-1. Localized to the cytosolic side of the endoplasmic reticulum and relocated to the Golgi apparatus upon viral infection, RSAD2 is thought to prevent viral budding by disrupting lipid rafts at the plasma membrane and supporting the Interferon-induced antiviral state of the cell. Additionally, RSAD2 can bind to and inactivate FDPS (an enzyme that is crucial for the synthesis of cholesterol and geranylated and farnesylated proteins), thereby playing a role in lipid synthesis. Overexpression of RSAD2 leads to abnormal lipid accumulation that is associated with atherosclerosis, a chronic inflammatory disease characterized by hardened arteries.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11284R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11284R-A647
Lokale Artikelnummer::
BOSSBS-11284R-A647
Beschreibung:
KSP37 is a 223 amino acid protein that is secreted into the extracellular space and belongs to the fibroblast growth factor-binding protein family. Expressed in serum, as well as in cytotoxic T lymphocytes and peripheral leukocytes, KSP37 is thought to be involved in lymphocyte-mediated immunity, possibly playing a role in the development of asthma. The gene encoding KSP37 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5371R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5371R-CY5.5
Lokale Artikelnummer::
BOSSBS-5371R-CY5.5
Beschreibung:
PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0540R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0540R-CY7
Lokale Artikelnummer::
BOSSBS-0540R-CY7
Beschreibung:
HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13223R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13223R-A555
Lokale Artikelnummer::
BOSSBS-13223R-A555
Beschreibung:
Fused toes protein homolog (FTS), also known as AKT-interacting protein (AKTIP) and Ft1, is a 292 amino acid protein that localizes to the cytoplasm and the cell membrane. A member of the ubiquitin-conjugating enzyme family, FTS binds directly to AKT1 to regulate apoptosis in a cell population. AKT1 is a protein that plays a critical role in a number of cellular responses, such as cell growth, protein synthesis, and antiapoptotic signaling. The interaction of FTS and AKT1 enhances the phosphorylation and activation of AKT1, which, through an AKT1/GSK-3∫/NFATc1 signaling cascade, results in the increased production of the proapoptotic hormone Fas ligand and thus an increase in apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15126R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15126R-CY7
Lokale Artikelnummer::
BOSSBS-15126R-CY7
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. C21orf59, also known as C21orf48, is a 290 amino acid protein and its gene product has been provisionally designated C21orf59 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11531R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11531R
Lokale Artikelnummer::
BOSSBS-11531R
Beschreibung:
NPW is a 165 amino acid secreted protein that is cleaved into two chains: neuropeptide W-23 (also designated NPW23 or L8) and neuropeptide W-30 (also known as NPW30 or L8C). Both NPW neuropeptides activate G-protein coupled receptors in the central nervous system to enhance cortisol secretion. Highly expressed in lymphoblastic leukemia, colorectal adenocarcinoma, fetal kidney, trachea and substantia nigra, NPW is also found at low levels in placenta, ovary, testis and uterus. NPW functions in organization of neuroendocrine signals and is also thought to enhance food and water intake as well as stress responses. The gene encoding NPW maps to human chromosome 16p13.3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11339R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11339R-A750
Lokale Artikelnummer::
BOSSBS-11339R-A750
Beschreibung:
Members of the calsyntenin protein family are localised to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12476R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12476R-A647
Lokale Artikelnummer::
BOSSBS-12476R-A647
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ANKZF1 (ankyrin repeat and zinc finger domain containing 1), also known as ZNF744, is 726 amino acids in length and lacks a KRAB domain but contains one C2H2-type zinc finger and two ANK repeats. The gene encoding ANKZF1 localizes to chromosome 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13623R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13623R-FITC
Lokale Artikelnummer::
BOSSBS-13623R-FITC
Beschreibung:
TMEM176A is a 235 amino acid multi-pass membrane protein belonging to the TMEM176 family. The gene encoding GS188 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11568R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11568R-CY7
Lokale Artikelnummer::
BOSSBS-11568R-CY7
Beschreibung:
HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterized by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1’s SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 signaling, HS1BP3 is likely involved in lymphocyte activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7115R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7115R-CY3
Lokale Artikelnummer::
BOSSBS-7115R-CY3
Beschreibung:
MLC1 is a 377 amino acid multi-pass membrane protein that may serve as a non-selective neuronal cation channel in brain. Mutant MLC1 proteins that show impaired folding have been corrected in vitro with the addition of a Ca(2+)-ATPase inhibitor, curcumin. Mutations in the gene encoding MLC1 is the cause of megalencephalic leukoencephalopathy with subcortical cysts, also known as van der Knaap disease, a rare syndrome characterized early in life by progressive brain destruction causing mental retardation and incoordination. Single nucleotide polymorphisms within the MLC1 gene may be associated with periodic catatonia, but there seems to be conflicting evidence on whether or not the gene is implicated in general schizophrenia.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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