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3-Chlor-5-propoxyphenylborons\\u00E4urepinakolester
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3-Chlor-5-propoxyphenylborons\\u00E4urepinakolester
Artikel-Nr:
(BOSSBS-12180R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12180R-A647
Lokale Artikelnummer::
BOSSBS-12180R-A647
Beschreibung:
The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down’s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12180R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12180R-A488
Lokale Artikelnummer::
BOSSBS-12180R-A488
Beschreibung:
The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down’s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3451R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3451R-A647
Lokale Artikelnummer::
BOSSBS-3451R-A647
Beschreibung:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3451R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3451R-FITC
Lokale Artikelnummer::
BOSSBS-3451R-FITC
Beschreibung:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0644R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0644R-CY5
Lokale Artikelnummer::
BOSSBS-0644R-CY5
Beschreibung:
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11296R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11296R
Lokale Artikelnummer::
BOSSBS-11296R
Beschreibung:
17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase type 4) is also known as peroxisomal multifunctional enzyme/protein 2 (MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
VE:
1 * 100 µl
Lieferant:
JULABO GmbH
Beschreibung:
The powerful and robust CORIO™ laboratory circulators provide the exact temperature, absolute precision and a wide working temperature range. The CORIO™ C immersion circulator is the basic model, it is ideal for standard internal applications, the CD model is more advanced and can used for temperature control of external applications if required. The jet nozzle allows continuous adjustment of the pump stream in the bath. The stainless steel baths are durable and have an integrated drain tap (except B5). These open heating bath circulators are ideal for temperature control of samples, preparation of samples for serology and clinical chemistry, analysis, and material testing. The CD-B units are ideal for external temperature control applications in combination with measuring instruments, measuring cells, photometers, refractometers and polarimeters.
Lieferant:
Thermo Scientific
Beschreibung:
(2-Chlorethyl)diethylammoniumchlorid 99.5%
Artikel-Nr:
(BOSSBS-5285R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5285R-CY3
Lokale Artikelnummer::
BOSSBS-5285R-CY3
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11695R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11695R-A750
Lokale Artikelnummer::
BOSSBS-11695R-A750
Beschreibung:
The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe²⁺ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11695R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11695R
Lokale Artikelnummer::
BOSSBS-11695R
Beschreibung:
The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
4-Methoxyphenylhydraziniumchlorid 98%
Artikel-Nr:
(K830-100ML)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRCK830-100ML
Beschreibung:
Gebrauchsfertiges, empfindliches Substrat für die Detektion von HRP (Meerrettichperoxidase)-Aktivität. Ideal für ELISA und Lösungsproben. Zeigt ein schnelleres Signal, gesteigerte Empfindlichkeit und geringstmöglichen Hintergrund.
VE:
1 * 100 mL
Artikel-Nr:
(BOSSBS-13354R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13354R-FITC
Lokale Artikelnummer::
BOSSBS-13354R-FITC
Beschreibung:
Growth hormone 2 (GH2) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. The major role of GH2 in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13354R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13354R-A350
Lokale Artikelnummer::
BOSSBS-13354R-A350
Beschreibung:
Growth hormone 2 (GH2) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. The major role of GH2 in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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