tert-Butyl+2-(ethylamino)acetate
Artikel-Nr:
(BOSSBS-13257R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13257R-A488
Lokale Artikelnummer::
BOSSBS-13257R-A488
Beschreibung:
GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13257R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13257R-A350
Lokale Artikelnummer::
BOSSBS-13257R-A350
Beschreibung:
GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12085R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12085R-A647
Lokale Artikelnummer::
BOSSBS-12085R-A647
Beschreibung:
Gamma-aminobutyric acid (GABA) receptors are pentameric membrane proteins that operate GABA-gated chloride channels and inhibit neurotransmission in the central nervous system. The rho receptor subunits do not exhibit sensitivity to typical GABA receptor modulators such as bicuculline, hexobarbital, and diazepam. While the rho 1 subunit localizes specifically to the retina, rho 2 expresses in all regions of the brain, though levels were still highest in the retina, implying a role for both subunits in visual pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5358R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5358R-CY3
Lokale Artikelnummer::
BOSSBS-5358R-CY3
Beschreibung:
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5358R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5358R
Lokale Artikelnummer::
BOSSBS-5358R
Beschreibung:
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].
VE:
1 * 100 µl
Lieferant:
MP Biomedicals
Beschreibung:
Soluble in water.
Artikel-Nr:
(BOSSBS-1350R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-HRP
Lokale Artikelnummer::
BOSSBS-1350R-HRP
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(USBI040964)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040964
Lokale Artikelnummer::
USBI040964
Beschreibung:
Anti-RET Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(PRSI90-328)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-328
Lokale Artikelnummer::
PRSI90-328
Beschreibung:
Soluble, stable and more potent angiopoietin-1 (Ang-1) variant.
VE:
1 * 10 µG
Artikel-Nr:
(BOSSBS-5358R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5358R-A647
Lokale Artikelnummer::
BOSSBS-5358R-A647
Beschreibung:
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11019R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11019R-HRP
Lokale Artikelnummer::
BOSSBS-11019R-HRP
Beschreibung:
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2605R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2605R-A680
Lokale Artikelnummer::
BOSSBS-2605R-A680
Beschreibung:
IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3382R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3382R-A555
Lokale Artikelnummer::
BOSSBS-3382R-A555
Beschreibung:
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5683R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5683R-FITC
Lokale Artikelnummer::
BOSSBS-5683R-FITC
Beschreibung:
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
VE:
1 * 100 µl
Lieferant:
Thermo Orion
Beschreibung:
Orion™ AQUAfast™ Auto-Test Ampoule Reagents can be used with the Orion™ AQUAfast™ AQ4000 colorimeter to simplify sample preparation and tests.
Artikel-Nr:
(BOSSBS-5398R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5398R
Lokale Artikelnummer::
BOSSBS-5398R
Beschreibung:
IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.
VE:
1 * 100 µl
Preis auf Anfrage
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