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2',3'-Didehydro-3'-deoxythymidine
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2',3'-Didehydro-3'-deoxythymidine
Artikel-Nr:
(BOSSBS-3215R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3215R-A555
Lokale Artikelnummer::
BOSSBS-3215R-A555
Beschreibung:
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.
VE:
1 * 100 µl
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Tetramethylrhodamine isothiocyanate Isomer R (TRITC) is the R isomer of tetramethylrhodamine isothiocyanate and is also known as 6-tetramethylrhodamine isothiocyanate. It is a strongly fluorescent compound soluble in ethanol, methanol, dimethylformamide, dimethylsulfoxide, and water. TRITC is a moderately-sized aminoxanthene dye carrying carboxylic acid and isothiocyanate substituents on the non-planar pendant phenyl ring. It forms a lipophilic cation in acidic pH and a hydrophilic zwitterion around neutral pH. The isothiocyanate group reacts with nucleophilic substituents (e.g., amino, hydroxyl, thiol) of biomolecules, providing the means of attaching a fluorescent label. TRITC also reacts with water and hydroxide ions and is unstable in aqueous solutions. TRITC is commercially available as a zwitterion or as a chloride.
Artikel-Nr:
(BOSSBS-0855R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0855R-A750
Lokale Artikelnummer::
BOSSBS-0855R-A750
Beschreibung:
Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds.Belongs to the insulin family. The insulin-link growth factors, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, respectvely), share approximatly 76% sequence identity and are 50% related to pro-insulin.IGF-I and IGF-II are nonglycosylated, single chain proteins of 70 and 76 amino acids in length, respectivelly. IGF-I functions as an autocrine regulator of growth in vaious, whereas the function of IGF-II is less well defined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8243R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8243R-A680
Lokale Artikelnummer::
BOSSBS-8243R-A680
Beschreibung:
The coupling of ubiquitin conjugation to endoplasmic reticulum (ER) degradation (CUE) domain functions as a ubiquitin (UB) binding domain that is approximately 40 amino acids in length. Present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways, CUE domains can bind monoubiquitin and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker. Two isoforms of CUEDC1 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8243R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8243R-CY5
Lokale Artikelnummer::
BOSSBS-8243R-CY5
Beschreibung:
The coupling of ubiquitin conjugation to endoplasmic reticulum (ER) degradation (CUE) domain functions as a ubiquitin (UB) binding domain that is approximately 40 amino acids in length. Present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways, CUE domains can bind monoubiquitin and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker. Two isoforms of CUEDC1 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11853R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11853R-CY7
Lokale Artikelnummer::
BOSSBS-11853R-CY7
Beschreibung:
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. HMX2 (H6 family homeobox 2), also known as H6L or Nkx5-2, is a 273 amino acid nuclear protein that belongs to the HMX homeobox family and contains one homeobox DNA-binding domain. HMX2 functions as a transcription factor that assists in specification of neuronal cell types and is essential for proper development of hypothalamus and inner ear. Hemizygous deletions of the gene encoding HMX2 are thought to lead to vestibular dysfunction, inner ear malformations and congenital sensorineural hearing loss.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11695R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11695R-CY5
Lokale Artikelnummer::
BOSSBS-11695R-CY5
Beschreibung:
The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11853R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11853R-CY3
Lokale Artikelnummer::
BOSSBS-11853R-CY3
Beschreibung:
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. HMX2 (H6 family homeobox 2), also known as H6L or Nkx5-2, is a 273 amino acid nuclear protein that belongs to the HMX homeobox family and contains one homeobox DNA-binding domain. HMX2 functions as a transcription factor that assists in specification of neuronal cell types and is essential for proper development of hypothalamus and inner ear. Hemizygous deletions of the gene encoding HMX2 are thought to lead to vestibular dysfunction, inner ear malformations and congenital sensorineural hearing loss.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
6-Benzylaminopurin ≥99%
Artikel-Nr:
(BOSSBS-1873R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1873R-A750
Lokale Artikelnummer::
BOSSBS-1873R-A750
Beschreibung:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
VE:
1 * 100 µl
Artikel-Nr:
(APOSPC446052-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC446052-1G
Lokale Artikelnummer::
APOSPC446052-1G
Beschreibung:
[3-(4-Aminophenyl)-5-trifluoromethylpyridin-2-yl]dimethylamine
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Fmoc-L-Lys(N3)-OH ≥98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Tris(perfluorbutyl)amin
Artikel-Nr:
(CAYM14219-100)
Lieferant:
Cayman Chemical
Hersteller-Artikelnummer::
14219-100
Lokale Artikelnummer::
CAYM14219-100
Beschreibung:
Ubiquitin is a small protein composed of 76 amino acids and having a molecular weight of 8.6 kDa.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-8259R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8259R-A555
Lokale Artikelnummer::
BOSSBS-8259R-A555
Beschreibung:
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8259R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8259R-A680
Lokale Artikelnummer::
BOSSBS-8259R-A680
Beschreibung:
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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