5-Chloro-2-(trifluoromethyl)cinnamic+acid
Lieferant:
Thermo Scientific
Beschreibung:
Potassium thiosulphate hydrate 96+%, reinst
Artikel-Nr:
(SPCMPO170-500GM)
Lieferant:
Spectrum Chemical
Hersteller-Artikelnummer::
PO170-500GM
Lokale Artikelnummer::
SPCMPO170-500GM
Beschreibung:
Potassium Chloride, Granular, USP is used to treat hypokalemia. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
VE:
1 * 500 g
Artikel-Nr:
(BOSSBS-1091R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1091R-A750
Lokale Artikelnummer::
BOSSBS-1091R-A750
Beschreibung:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
VE:
1 * 100 µl
Lieferant:
Spectrum Chemical
Beschreibung:
Acesulfame potassium is a sugar substitute that contains no calories and is a white crystalline powder.
Artikel-Nr:
(BOSSBS-6719R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6719R
Lokale Artikelnummer::
BOSSBS-6719R
Beschreibung:
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4775R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4775R-A750
Lokale Artikelnummer::
BOSSBS-4775R-A750
Beschreibung:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3401R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3401R-CY5.5
Lokale Artikelnummer::
BOSSBS-3401R-CY5.5
Beschreibung:
PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3401R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3401R-A488
Lokale Artikelnummer::
BOSSBS-3401R-A488
Beschreibung:
PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4775R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4775R
Lokale Artikelnummer::
BOSSBS-4775R
Beschreibung:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1293R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1293R-A750
Lokale Artikelnummer::
BOSSBS-1293R-A750
Beschreibung:
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1293R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1293R-CY5.5
Lokale Artikelnummer::
BOSSBS-1293R-CY5.5
Beschreibung:
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3401R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3401R-A555
Lokale Artikelnummer::
BOSSBS-3401R-A555
Beschreibung:
PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Potassium oxonate
Artikel-Nr:
(BOSSBS-20649R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-20649R-A680
Lokale Artikelnummer::
BOSSBS-20649R-A680
Beschreibung:
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-20649R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-20649R-A750
Lokale Artikelnummer::
BOSSBS-20649R-A750
Beschreibung:
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5933R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5933R-CY5
Lokale Artikelnummer::
BOSSBS-5933R-CY5
Beschreibung:
KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons' membrane potential and in resting K+ currents.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||