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4-(Difluormethoxy)phenylessigsäure
Artikel-Nr:
(PRSI77-050)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-050
Lokale Artikelnummer::
PRSI77-050
Beschreibung:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 to 17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI29-366)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-366
Lokale Artikelnummer::
PRSI29-366
Beschreibung:
PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This intronless gene is thought to be generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-907)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-907
Lokale Artikelnummer::
PRSI33-907
Beschreibung:
This antibody recognises an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 antibody with a GCDFP-15 antibody is valuable in the diagnosis of apocrine carcinoma.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI91-358)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-358
Lokale Artikelnummer::
PRSI91-358
Beschreibung:
Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-882)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-882
Lokale Artikelnummer::
PRSI91-882
Beschreibung:
Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI77-051)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-051
Lokale Artikelnummer::
PRSI77-051
Beschreibung:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 to 17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI77-052)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-052
Lokale Artikelnummer::
PRSI77-052
Beschreibung:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 to 17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI77-048)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-048
Lokale Artikelnummer::
PRSI77-048
Beschreibung:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 to 17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI77-045)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-045
Lokale Artikelnummer::
PRSI77-045
Beschreibung:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 to 17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
VE:
1 * 0,1 mg
New Product
Lieferant:
HUBER
Beschreibung:
Viele Anwendungen hängen von einer zuverlässigen Kühlquelle ab. Die Umlaufkühler der Unichiller® Serie bieten eine ideale Lösung für die umweltfreundliche und wirtschaftliche Kühlung in Labor und Industrie. Es stehen mehr als 50 luft- und wassergekühlte Modelle zur Auswahl, mit Kühlleistungen von 0,3 bis 50 kW. Ein effizientes Energiemanagement sorgt für niedrige Betriebskosten und weniger Verbrauch von wertvollem Frischwasser. Huber Umlaufkühler reduzieren den Ressourcenverbrauch und stellen eine Investition dar, die sich schnell auszahlt.
Lieferant:
MP Biomedicals
Beschreibung:
Dark Green almost Black Fine Powder
Artikel-Nr:
(466-0488)
Lieferant:
Binder
Hersteller-Artikelnummer::
9010-0292
Lokale Artikelnummer::
BIND9010-0292
Beschreibung:
Diese Trockenschränke für begrenzte Mengen Lösungsmittel haben eine hohe Temperaturgenauigkeit und silikon- und staubfreie Edelstahlkammern. Die Geräte werden häufig bei der Qualitätssicherung von Farben und anderen flüssigen Beschichtungsmitteln eingesetzt. FDL-Schränke besitzen einen MP-Regler mit einstellbarer Rampenfunktion und integrierter Zeitschaltuhr auf wöchentlicher Basis mit Echtzeitfunktion.
VE:
1 * 1 ST
Artikel-Nr:
(PRSI92-684)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-684
Lokale Artikelnummer::
PRSI92-684
Beschreibung:
Tumour Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumour necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumour growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial cells. TNFSF15 is also able to regulate the expression of several important genes involved in angiogenesis. These findings are consistent with the view that TNFSF15 functions as an autocrine cytokine to inhibit angiogenesis and stabilise the vasculature.
VE:
1 * 50 µG
Lieferant:
Corning
Beschreibung:
The Axypet® pro pipettors have been engineered to provide the highest levels of comfort, accuracy and precision. Lightweight construction, contoured shape of the handle and four digit counter were designed to guarantee comfortable pipetting. All pipettors feature smooth plunger movement and extremely low pipetting forces to reduce the wrist strain and fatigue (RSI). Colour-coded push buttons help to identify the size of the pipettor.
Lieferant:
FINNZYMES REAGENTS
Beschreibung:
Phire® Hot Start II DNA Polymerase is faster, extremely robust, and capable of amplifying long DNA fragments with high yields. Phire® Hot Start II DNA Polymerase incorporates a dsDNA-binding domain which allows short extension times (10 to 15 s/kb), improves yields, and increases fidelity 2-fold compared to <i>Taq</i> DNA polymerase. In addition, the Hot Start technology allows complete reactivation of the enzyme in “zero-time” at standard cycling temperatures. This combination of features makes the polymerase an ideal solution for routine and high throughput PCR applications. Phire® Hot Start II DNA Polymerase delivers superior performance in conventional thermal cyclers as well as in fast instruments, such as the Piko® Thermal Cycler.
Artikel-Nr:
(SARS01.1606.001)
Lieferant:
SARSTEDT
Hersteller-Artikelnummer::
01.1606.001
Lokale Artikelnummer::
SARS01.1606.001
Beschreibung:
Blood collecting system with sodium citrate coagulation activator.
VE:
1 * 500 ST
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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