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Potassium+trifluoro(oxetan-3-yl)borate
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Potassium+trifluoro(oxetan-3-yl)borate
Artikel-Nr:
(BOSSBS-3327R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3327R
Lokale Artikelnummer::
BOSSBS-3327R
Beschreibung:
Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2 and RPS6KA3), cyclic AMP-dependent protein kinase (PRKACA), protein kinase C (PRKCD and PRKCZ), serum and glucocorticoid-inducible kinase (SGK1, SGK2 and SGK3), p21-activated kinase-1 (PAK1), protein kinase PKN (PKN1 and PKN2). Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, thus propagating the signal to downstream targets controlling cell proliferation and survival, as well as glucose and amino acid uptake and storage. Negatively regulates the TGF-beta-induced signaling by: modulating the association of SMAD3 and SMAD7 with TGF-beta receptor, phosphorylating SMAD2, SMAD3, SMAD4 and SMAD7, preventing the nuclear translocation of SMAD3 and SMAD4 and the translocation of SMAD7 from the nucleus to the cytoplasm in response to TGF-beta. Activates PPARG transcriptional activity and promotes adipocyte differentiation. Activates the NF-kappa-B pathway via phosphorylation of IKKB. The tyrosine phosphorylated form is crucial for the regulation of focal adhesions by angiotensin II. Controls proliferation, survival, and growth of developing pancreatic cells. Participates in the regulation of Ca(2+) entry and Ca(2+)-activated K(+) channels of mast cells. Essential for the motility of vascular endothelial cells (ECs) and is involved in the regulation of their chemotaxis. Plays a critical role in cardiac homeostasis by serving as a dual effector for cell survival and beta-adrenergic response. Plays an important role during thymocyte development by regulating the expression of key nutrient receptors on the surface of pre-T cells and mediating Notch-induced cell growth and proliferative responses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1152R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1152R-CY3
Lokale Artikelnummer::
BOSSBS-1152R-CY3
Beschreibung:
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3327R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3327R-CY7
Lokale Artikelnummer::
BOSSBS-3327R-CY7
Beschreibung:
Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2 and RPS6KA3), cyclic AMP-dependent protein kinase (PRKACA), protein kinase C (PRKCD and PRKCZ), serum and glucocorticoid-inducible kinase (SGK1, SGK2 and SGK3), p21-activated kinase-1 (PAK1), protein kinase PKN (PKN1 and PKN2). Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, thus propagating the signal to downstream targets controlling cell proliferation and survival, as well as glucose and amino acid uptake and storage. Negatively regulates the TGF-beta-induced signaling by: modulating the association of SMAD3 and SMAD7 with TGF-beta receptor, phosphorylating SMAD2, SMAD3, SMAD4 and SMAD7, preventing the nuclear translocation of SMAD3 and SMAD4 and the translocation of SMAD7 from the nucleus to the cytoplasm in response to TGF-beta. Activates PPARG transcriptional activity and promotes adipocyte differentiation. Activates the NF-kappa-B pathway via phosphorylation of IKKB. The tyrosine phosphorylated form is crucial for the regulation of focal adhesions by angiotensin II. Controls proliferation, survival, and growth of developing pancreatic cells. Participates in the regulation of Ca(2+) entry and Ca(2+)-activated K(+) channels of mast cells. Essential for the motility of vascular endothelial cells (ECs) and is involved in the regulation of their chemotaxis. Plays a critical role in cardiac homeostasis by serving as a dual effector for cell survival and beta-adrenergic response. Plays an important role during thymocyte development by regulating the expression of key nutrient receptors on the surface of pre-T cells and mediating Notch-induced cell growth and proliferative responses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3327R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3327R-A750
Lokale Artikelnummer::
BOSSBS-3327R-A750
Beschreibung:
Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2 and RPS6KA3), cyclic AMP-dependent protein kinase (PRKACA), protein kinase C (PRKCD and PRKCZ), serum and glucocorticoid-inducible kinase (SGK1, SGK2 and SGK3), p21-activated kinase-1 (PAK1), protein kinase PKN (PKN1 and PKN2). Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, thus propagating the signal to downstream targets controlling cell proliferation and survival, as well as glucose and amino acid uptake and storage. Negatively regulates the TGF-beta-induced signaling by: modulating the association of SMAD3 and SMAD7 with TGF-beta receptor, phosphorylating SMAD2, SMAD3, SMAD4 and SMAD7, preventing the nuclear translocation of SMAD3 and SMAD4 and the translocation of SMAD7 from the nucleus to the cytoplasm in response to TGF-beta. Activates PPARG transcriptional activity and promotes adipocyte differentiation. Activates the NF-kappa-B pathway via phosphorylation of IKKB. The tyrosine phosphorylated form is crucial for the regulation of focal adhesions by angiotensin II. Controls proliferation, survival, and growth of developing pancreatic cells. Participates in the regulation of Ca(2+) entry and Ca(2+)-activated K(+) channels of mast cells. Essential for the motility of vascular endothelial cells (ECs) and is involved in the regulation of their chemotaxis. Plays a critical role in cardiac homeostasis by serving as a dual effector for cell survival and beta-adrenergic response. Plays an important role during thymocyte development by regulating the expression of key nutrient receptors on the surface of pre-T cells and mediating Notch-induced cell growth and proliferative responses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12864R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12864R-A750
Lokale Artikelnummer::
BOSSBS-12864R-A750
Beschreibung:
Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesised as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine Signalling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumour growth progression.
VE:
1 * 100 µl
Artikel-Nr:
(ABCAAB222131-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB222131-100
Lokale Artikelnummer::
ABCAAB222131-100
Beschreibung:
Anti-TGIF2 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-6005R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6005R-A680
Lokale Artikelnummer::
BOSSBS-6005R-A680
Beschreibung:
EXTL2 is a glycosyltransferase required for the biosynthesis of heparan-sulfate and is responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
VE:
1 * 100 µl
Artikel-Nr:
(USBIT8250-31C)
Lieferant:
US Biological
Hersteller-Artikelnummer::
T8250-31C
Lokale Artikelnummer::
USBIT8250-31C
Beschreibung:
Anti-TGFBR1 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(APOSBIM2043-25MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BIM2043-25MG
Lokale Artikelnummer::
APOSBIM2043-25MG
Beschreibung:
4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt
VE:
1 * 25 mg
Artikel-Nr:
(USBIB0901-01C-100)
Lieferant:
US Biological
Hersteller-Artikelnummer::
B0901-01C-100
Lokale Artikelnummer::
USBIB0901-01C-100
Beschreibung:
Anti-DEFB4A Sheep polyclonal antibody unconjugated
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3548R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3548R-CY5
Lokale Artikelnummer::
BOSSBS-3548R-CY5
Beschreibung:
Dystrobrevin beta is a component of the dystrophin-associated protein complex and interacts with dystrophin short form DP71, syntrophins SNTG1 and SNTG2. It localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. 4 isoforms produced by alternative splicing have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3548R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3548R-CY7
Lokale Artikelnummer::
BOSSBS-3548R-CY7
Beschreibung:
Dystrobrevin beta is a component of the dystrophin-associated protein complex and interacts with dystrophin short form DP71, syntrophins SNTG1 and SNTG2. It localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. 4 isoforms produced by alternative splicing have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5774R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5774R-CY7
Lokale Artikelnummer::
BOSSBS-5774R-CY7
Beschreibung:
The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to insulin, also known as ADSF) is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like a is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, Resistin-like b, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like b expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5774R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5774R-CY3
Lokale Artikelnummer::
BOSSBS-5774R-CY3
Beschreibung:
The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to insulin, also known as ADSF) is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like a is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, Resistin-like b, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like b expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12854R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12854R-A680
Lokale Artikelnummer::
BOSSBS-12854R-A680
Beschreibung:
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12856R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12856R-A680
Lokale Artikelnummer::
BOSSBS-12856R-A680
Beschreibung:
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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