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2-Amino-4,6-bis(trifluoromethyl)nicotinamide
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2-Amino-4,6-bis(trifluoromethyl)nicotinamide
Lieferant:
VWR Chemicals
Beschreibung:
HES Lösung gebrauchsfertig für die Histologie
Lieferant:
COMBI-BLOCKS
Beschreibung:
4,4-Dimethylcyclohex-2-en-1-on-2-ylboronsäurepinakolester
Artikel-Nr:
(BOSSBS-5933R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5933R-CY3
Lokale Artikelnummer::
BOSSBS-5933R-CY3
Beschreibung:
KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons' membrane potential and in resting K+ currents.
VE:
1 * 100 µl
Artikel-Nr:
(12902-20KG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
12902-20KG
Lokale Artikelnummer::
HONC12902-20KG
Beschreibung:
Potassium hexacyanocobaltate(III) ≥97,0%, Fluka™
VE:
1 * 20 kg
Artikel-Nr:
(BOSSBS-0533R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0533R
Lokale Artikelnummer::
BOSSBS-0533R
Beschreibung:
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Calcium is required for high affinity binding to GABA. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception. Activated by (-)-baclofen, cgp27492 and blocked by phaclofen. Isoform 1E may regulate the formation of functional GABBR1/GABBR2 heterodimers by competing for GABBR2 binding. This could explain the observation that certain small molecule ligands exhibit differential affinity for central versus peripheral sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3396R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3396R-CY3
Lokale Artikelnummer::
BOSSBS-3396R-CY3
Beschreibung:
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3397R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3397R-A555
Lokale Artikelnummer::
BOSSBS-3397R-A555
Beschreibung:
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
VE:
1 * 100 µl
Artikel-Nr:
(201987-100G)
Lieferant:
SIGMA ALDRICH MICROSCOPY
Hersteller-Artikelnummer::
201987-100G
Lokale Artikelnummer::
SIAM201987-100G
Beschreibung:
Acid yellow-17 (C.I. 18965), also known as Disodium 2, 5-dichloro-4-(5-hydroxy-3-methyl-4-(sulphophenylazo)pyrazol-1-yl) benzenesulphonate, and Yellow 2G is an anionic, reactive textile dye. This synthetic azo dye possesses a stable aromatic structure with SO₃H and OH groups. The applications of Acid yellow-17 are seen in detergent, soap, textile, printing, and cosmetic industries.
VE:
1 * 100 g
Artikel-Nr:
(BOSSBS-3712R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3712R-CY3
Lokale Artikelnummer::
BOSSBS-3712R-CY3
Beschreibung:
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4775R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4775R-FITC
Lokale Artikelnummer::
BOSSBS-4775R-FITC
Beschreibung:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4775R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4775R-A488
Lokale Artikelnummer::
BOSSBS-4775R-A488
Beschreibung:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4775R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4775R-A350
Lokale Artikelnummer::
BOSSBS-4775R-A350
Beschreibung:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3349R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3349R-FITC
Lokale Artikelnummer::
BOSSBS-3349R-FITC
Beschreibung:
postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3349R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3349R-A350
Lokale Artikelnummer::
BOSSBS-3349R-A350
Beschreibung:
postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3349R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3349R-A488
Lokale Artikelnummer::
BOSSBS-3349R-A488
Beschreibung:
postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3396R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3396R-HRP
Lokale Artikelnummer::
BOSSBS-3396R-HRP
Beschreibung:
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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