Adenosin-5'-monophosphorsäure+(AMP)+Monohydrat
Artikel-Nr:
(116802-10)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
116802-10
Lokale Artikelnummer::
CALB116802-10
Beschreibung:
A potent cell-permeable activator of cAMP-dependent protein kinase (PKA). Due to its considerably increased lipophilicity, it has sufficient membrane permeability for many biological systems.
VE:
1 * 10 µmol
Artikel-Nr:
(HONE04415.9050)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
04415.9050
Lokale Artikelnummer::
HONE04415.9050
Beschreibung:
Natriumphosphinat Monohydrat 99-103%, puriss. DAC, reinst, Fluka™
VE:
1 * 50 kg
Artikel-Nr:
(BOSSBS-1116R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1116R-A680
Lokale Artikelnummer::
BOSSBS-1116R-A680
Beschreibung:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodelling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1769R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1769R-CY5
Lokale Artikelnummer::
BOSSBS-1769R-CY5
Beschreibung:
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3146R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3146R-A350
Lokale Artikelnummer::
BOSSBS-3146R-A350
Beschreibung:
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1769R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1769R-FITC
Lokale Artikelnummer::
BOSSBS-1769R-FITC
Beschreibung:
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3146R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3146R-FITC
Lokale Artikelnummer::
BOSSBS-3146R-FITC
Beschreibung:
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1769R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1769R-HRP
Lokale Artikelnummer::
BOSSBS-1769R-HRP
Beschreibung:
Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
β-(N-Morpholino)ethansulfonsäure (MES) Monohydrat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Mangan(II)chlorid Monohydrat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-2959R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2959R-CY3
Lokale Artikelnummer::
BOSSBS-2959R-CY3
Beschreibung:
Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
Citronensäure Monohydrat 99,5-100,5% (alkalimetrisch, berechnet an wasserfreien Substanzen), Kristalle, EMPROVE® EXPERT Ph. Eur., BP, JP, USP, ACS, SAFC®
Lieferant:
Alfa Aesar
Beschreibung:
Natriumperchlorat Monohydrat ≥85,0-90,0% ACS
Artikel-Nr:
(1.05911.9029)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.05911.9029
Lokale Artikelnummer::
MERP1.05911.9029
Beschreibung:
Maltose Monohydrat ≥95,0% (durch HPLC), EMPROVE® ESSENTIAL, SAFC®
VE:
1 * 25 kg
Artikel-Nr:
(SIAL229040-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
229040-1G
Lokale Artikelnummer::
SIAL229040-1G
Beschreibung:
Platin(IV)oxid Monohydrat, Sigma-Aldrich®
VE:
1 * 1 g
Lieferant:
Thermo Scientific
Beschreibung:
1-Hexansulfonsäure Natriumsalz Monohydrat 98% für die HPLC
Preis auf Anfrage
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