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Methyl+3-(4,5-dimethoxy-2-nitrophenyl)acrylate
Artikel-Nr:
(F5803-50MG)
Lieferant:
SIGMA ALDRICH MICROSCOPY
Hersteller-Artikelnummer::
F5803-50MG
Lokale Artikelnummer::
SIAMF5803-50MG
Beschreibung:
A preweighed vial containing 50 mg o-Dianisidine. o-Dianisidine (3,3′-dimethoxybenzidine) is a peroxidase substrate suitable for use in ELISA procedures. This substrate produces a soluble end product that is yellow-orange in color and can be read spectrophotometrically at 405 nm. The reaction may be stopped with 5 M HCl.
VE:
1 * 50 mg
Artikel-Nr:
(J583-25MG)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRCJ583-25MG
Beschreibung:
Eine Asparaginsäureprotease Inhibitor von Pepsin, Renin und Cathepsin D. Kann auch die HIV Protease blockieren. Nicht wasserlöslich.
VE:
1 * 25 mg
Lieferant:
G-Biosciences
Beschreibung:
For the rapid purification of soluble, 6X His or GST tagged proteins.
Artikel-Nr:
(BOSSBS-4117R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4117R-FITC
Lokale Artikelnummer::
BOSSBS-4117R-FITC
Beschreibung:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9308R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9308R-CY7
Lokale Artikelnummer::
BOSSBS-9308R-CY7
Beschreibung:
Microtubules are polymers of alpha and beta subunits that form the mitotic spindle and assist in the organization of membranous organelles during interphase. Katanin p60 A1, also known as KATNA1, is a 491 amino acid protein that belongs to the AAA ATPase family and is involved in microtubule regulation. Localized to the cytoplasm and to the centrosome, Katanin p60 A1 functions to sever and disassemble microtubules in an ATP-dependent manner, thus promoting the rapid reorganization of cellular microtubule arrays and playing an important role in microtubule release from the centrosome after nucleation. Katanin p60 A1, which exists as two alternatively spliced isoforms, can homooligomerize into hexameric rings whose activity is stimulated by the presence of microtubules.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0666R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0666R-A488
Lokale Artikelnummer::
BOSSBS-0666R-A488
Beschreibung:
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling (By similarity).
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
A dried yeast autolysate with a high content of amino nitrogen and water soluble B-complex vitamins.
Artikel-Nr:
(BOSSBS-4894R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4894R-A350
Lokale Artikelnummer::
BOSSBS-4894R-A350
Beschreibung:
Catalyzes the transfer of sulfate to position 6 of galactose residues of keratan. It has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal galactose residues are sulfated. It also may function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. It participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains. Whereas chondroitin sulfate is widely distributed throughout the body, keratan sulfate is primarily expressed in cartilage (joints, trachea, intervertebral discs) and cornea.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9601R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9601R
Lokale Artikelnummer::
BOSSBS-9601R
Beschreibung:
Friedreich ataxia is a progressive neurodegenerative disorder caused by loss of function mutations in the frataxin gene. The human frataxin gene maps to chromosome 9q13.The frataxin gene encodes a mitochondrial protein of the same name. Frataxin assembles into a stable homopolymer with iron-binding capabilities. When expressed in E. Coli human frataxin binds iron atoms at a rate of 10 iron atoms per 1 molecule of the frataxin polymer. Thus, frataxin appears to function in some capacity for iron-storage for the mitochondria. Frataxin may also function as an activator of oxidative phosphorylation to increase mitochondrial membrane potential and elevate cellular ATP. Frataxin is expressed in tissues with high metabolic activity including heart, liver and brown fat.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1499R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1499R-HRP
Lokale Artikelnummer::
BOSSBS-1499R-HRP
Beschreibung:
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1499R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1499R-A350
Lokale Artikelnummer::
BOSSBS-1499R-A350
Beschreibung:
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1499R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1499R-A647
Lokale Artikelnummer::
BOSSBS-1499R-A647
Beschreibung:
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9308R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9308R-A750
Lokale Artikelnummer::
BOSSBS-9308R-A750
Beschreibung:
Microtubules are polymers of alpha and beta subunits that form the mitotic spindle and assist in the organisation of membranous organelles during interphase. Katanin p60 A1, also known as KATNA1, is a 491 amino acid protein that belongs to the AAA ATPase family and is involved in microtubule regulation. Localised to the cytoplasm and to the centrosome, Katanin p60 A1 functions to sever and disassemble microtubules in an ATP-dependent manner, thus promoting the rapid reorganisation of cellular microtubule arrays and playing an important role in microtubule release from the centrosome after nucleation. Katanin p60 A1, which exists as two alternatively spliced isoforms, can homooligomerise into hexameric rings whose activity is stimulated by the presence of microtubules.
VE:
1 * 100 µl
Artikel-Nr:
(111-1629)
Lieferant:
3M
Hersteller-Artikelnummer::
UF01014
Lokale Artikelnummer::
MMMAUF01014
Beschreibung:
Gehörschutzstöpsel mit Kabel aus einer patentierten Polymerformulierung, die bequeme dreifach geflanschte Spitze dieser Gehörschutzstöpsel bietet eine hervorragende Dämpfung von 35 dB SNR, eine der höchsten unter den vorgeformten Gehörschutzstöpseln. Die Ohrstöpsel sind bereits vorgeformt, um eine optimale Passform zu gewährleisten.
VE:
1 * 50 PAAR
Artikel-Nr:
(BNUM0946-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0946-50
Lokale Artikelnummer::
BTIUBNUM0946-50
Beschreibung:
This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-4117R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4117R-A350
Lokale Artikelnummer::
BOSSBS-4117R-A350
Beschreibung:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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