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POLYMER STANDARDS SERVICE
Artikel-Nr:
(BOSSBS-15482R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15482R-FITC
Lokale Artikelnummer::
BOSSBS-15482R-FITC
Beschreibung:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
VE:
1 * 100 µl
Artikel-Nr:
(1065210.)
Lieferant:
USP
Hersteller-Artikelnummer::
1065210
Lokale Artikelnummer::
USPH1065210
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 50 mg
Artikel-Nr:
(BOSSBS-12061R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12061R-CY7
Lokale Artikelnummer::
BOSSBS-12061R-CY7
Beschreibung:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7694R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7694R-CY7
Lokale Artikelnummer::
BOSSBS-7694R-CY7
Beschreibung:
Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7694R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7694R-CY5.5
Lokale Artikelnummer::
BOSSBS-7694R-CY5.5
Beschreibung:
Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption.
VE:
1 * 100 µl
Artikel-Nr:
(MOLEM78214946)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M78214946
Lokale Artikelnummer::
MOLEM78214946
Beschreibung:
Denatoniumbenzoat
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(85958.320)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC85958.320
Beschreibung:
Mineral oils are almost universally present in our environment. The main compounds of interest are mineral oil saturated hydrocarbons (MOSH) and mineral oil aromatic hydrocarbons (MOAH).
Both types are easily absorbed by the human body from food and can accumulate in body fat and in some organs.
VE:
1 * 2,5 L
Artikel-Nr:
(307904.400)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC307904.400
Beschreibung:
Geeignet für Tests in der Zuckerindustrie.
VE:
1 * 10 L
Lieferant:
Alfa Aesar
Beschreibung:
(Pentamethylcyclopentadienyl)iridium(III) dichloride dimer
Artikel-Nr:
(PRSIXW-7924)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-7924
Lokale Artikelnummer::
PRSIXW-7924
Beschreibung:
UPP1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. It is involved in the pathway of nucleotide and deoxyribonucleotide catabolism.
VE:
1 * 50 µG
Artikel-Nr:
(CHMPFL13762.POR)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL13762.POR
Lokale Artikelnummer::
CHMPFL13762.POR
Beschreibung:
2,5-Bis(trifluormethyl)benzylalkohol
VE:
1 * 1 ST
Artikel-Nr:
(SIAL319864-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
319864-5G
Lokale Artikelnummer::
SIAL319864-5G
Beschreibung:
(±)-1-Phenyl-2,2,2-trifluorethanol, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
Alfa Aesar
Beschreibung:
Amantadin Hydrochlorid 99%
Artikel-Nr:
(PRSI27-163)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-163
Lokale Artikelnummer::
PRSI27-163
Beschreibung:
Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 50 µG
Artikel-Nr:
(1553000.)
Lieferant:
USP
Hersteller-Artikelnummer::
1553000
Lokale Artikelnummer::
USPH1553000
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 200 mg
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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