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2-Bromo-4-fluorobenzylamine+hydrochloride
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2-Bromo-4-fluorobenzylamine+hydrochloride
Artikel-Nr:
(BOSSBS-9738R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9738R-CY7
Lokale Artikelnummer::
BOSSBS-9738R-CY7
Beschreibung:
Mapping to chromosome 21, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18. In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres. FASP1, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis. With expression in testis, FASP1 exists as a homodimer, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members. FASP1 has been shown to bind to pp5644 in Hela cells, where overexpression of pp5644 leads to inhibited growth and colony formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11674R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11674R-CY3
Lokale Artikelnummer::
BOSSBS-11674R-CY3
Beschreibung:
Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11473R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11473R
Lokale Artikelnummer::
BOSSBS-11473R
Beschreibung:
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8860R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8860R
Lokale Artikelnummer::
BOSSBS-8860R
Beschreibung:
CPOX is a 454 amino acid mitochondrial enzyme that is localized to the inner membrane space of erythrocytes. It participates in the sixth step of heme biosynthesis by catalyzing the formation of protoporphyrinogen IX from copropophyrinogen III. Mutations in the gene encoding CPOX are the cause of coproporphyria, an autosomal dominant disease characterized by skin photosensitivity and neurological disturbances. Symptoms are often experienced as attacks, which include severe abdominal and nerve pain. People affected by coproporphyria overexcrete copropophyrinogen III in feces and urine and the enzymatic activity of CPOX is found to be approximately half that of normal, leading to a decrease in overall heme synthesis. There is no cure for coproporphyria, but preventative treatment to relieve symptoms usually involves dietary changes and avoidance of drugs and alcohol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11674R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11674R-CY7
Lokale Artikelnummer::
BOSSBS-11674R-CY7
Beschreibung:
Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
VE:
1 * 100 µl
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Brilliant Blue G has been used for determining the urine protein concentration. It has been used for the protein band detection after SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis). It has been used as a P2X7R (purinergic receptor) antagonist.
Artikel-Nr:
(APOSPC400501-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC400501-250MG
Lokale Artikelnummer::
APOSPC400501-250MG
Beschreibung:
Ethyl 3-{[(trifluoromethyl)sulphonyl]oxy}furo[2,3-c]pyridine-2-carboxylate
VE:
1 * 250 mg
Artikel-Nr:
(BLDPBD216796-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD216796-1G
Lokale Artikelnummer::
BLDPBD216796-1G
Beschreibung:
(3S,4R)-1-tert-Butyl 3-ethyl 4-hydroxypyrrolidine-1,3-dicarboxylate 98%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
L-Norvaline ethyl ester hydrochloride 95%
Artikel-Nr:
(BNUM0794-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0794-50
Lokale Artikelnummer::
BTIUBNUM0794-50
Beschreibung:
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
VE:
1 * 50 µl
Artikel-Nr:
(APOSOR32595-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR32595-1G
Lokale Artikelnummer::
APOSOR32595-1G
Beschreibung:
Ethyl 4-[(1-oxo-2,3-dihydro-1H-isoindol-2-yl)methyl]benzoate, tech
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD316361-100MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD316361-100MG
Lokale Artikelnummer::
BLDPBD316361-100MG
Beschreibung:
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-(2-(tritylthio)ethyl)glycine 95%
VE:
1 * 100 mg
Artikel-Nr:
(HONCE3017-100ML)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
E3017-100ML
Lokale Artikelnummer::
HONCE3017-100ML
Beschreibung:
Certified Reference Material (CRM)
VE:
1 * 100 mL
Artikel-Nr:
(BOSSBS-10037R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10037R-A750
Lokale Artikelnummer::
BOSSBS-10037R-A750
Beschreibung:
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13731R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13731R-A350
Lokale Artikelnummer::
BOSSBS-13731R-A350
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH21 (protocadherin 21), also known as PRCAD, is an 859 amino acid single-pass membrane protein that localizes to the outer segments of photoreceptor cells and contains six cadherin domains. Existing as multiple alternatively spliced isoforms, PCDH21 functions as a calcium-dependent cell adhesion protein that is thought to be required for the structural integrity of photoreceptor cells and may be involved in the formation and maintenance of neuronal networks.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1814R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1814R-A647
Lokale Artikelnummer::
BOSSBS-1814R-A647
Beschreibung:
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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