Ethyl-2-naphthoyl+formate
Artikel-Nr:
(BOSSBS-7531R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7531R-A555
Lokale Artikelnummer::
BOSSBS-7531R-A555
Beschreibung:
The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesn’t bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3460R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3460R-CY5.5
Lokale Artikelnummer::
BOSSBS-3460R-CY5.5
Beschreibung:
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13161R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13161R-HRP
Lokale Artikelnummer::
BOSSBS-13161R-HRP
Beschreibung:
Fibulin-7 is a 439 amino acid extracellular matrix protein that belongs to the Fibulin family. Containing two EGF-like domains and one sushi (CCP/SCR) domain, Fibulin-7 exists as four alternatively spliced isoforms. Fibulin-7 is considered an adhesion protein that interacts with extracellular matrix molecules in developing teeth, and may be involved in differentiation and maintenance of odontoblasts as well as in dentin formation. Fibulin-7 is post-translationally glycosylated with N-linked oligosaccharides and interacts with heparin, fibronectin, fibulin-1 and DSP (dentin sialophosphoprotein). Fibulin-7 is encoded by a gene located on human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13161R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13161R-A647
Lokale Artikelnummer::
BOSSBS-13161R-A647
Beschreibung:
Fibulin-7 is a 439 amino acid extracellular matrix protein that belongs to the Fibulin family. Containing two EGF-like domains and one sushi (CCP/SCR) domain, Fibulin-7 exists as four alternatively spliced isoforms. Fibulin-7 is considered an adhesion protein that interacts with extracellular matrix molecules in developing teeth, and may be involved in differentiation and maintenance of odontoblasts as well as in dentin formation. Fibulin-7 is post-translationally glycosylated with N-linked oligosaccharides and interacts with heparin, fibronectin, fibulin-1 and DSP (dentin sialophosphoprotein). Fibulin-7 is encoded by a gene located on human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0666R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0666R-A647
Lokale Artikelnummer::
BOSSBS-0666R-A647
Beschreibung:
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0666R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0666R-FITC
Lokale Artikelnummer::
BOSSBS-0666R-FITC
Beschreibung:
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0666R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0666R-CY5.5
Lokale Artikelnummer::
BOSSBS-0666R-CY5.5
Beschreibung:
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling (By similarity).
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl 2-(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)acetate 95%
Artikel-Nr:
(BOSSBS-0693R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0693R-CY5.5
Lokale Artikelnummer::
BOSSBS-0693R-CY5.5
Beschreibung:
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15134R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15134R-CY7
Lokale Artikelnummer::
BOSSBS-15134R-CY7
Beschreibung:
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translo-acations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf26 gene product has been provisionally designated C22orf26 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3188R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3188R
Lokale Artikelnummer::
BOSSBS-3188R
Beschreibung:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fibre is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. Covalent modifications of the canonical core histones, including acetylation, phosphorylation, methylation, and monoubiquitination are used to mark nucleosomes to create chromatin domains with a range of functions. The information encoded by histone modifications can contribute to the formation and/or maintenance of transcriptionally active and inactive chromatin in response to various signalling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15131R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15131R-CY3
Lokale Artikelnummer::
BOSSBS-15131R-CY3
Beschreibung:
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf13 gene product has been provisionally designated C22orf13 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15134R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15134R-CY5
Lokale Artikelnummer::
BOSSBS-15134R-CY5
Beschreibung:
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translo-acations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf26 gene product has been provisionally designated C22orf26 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11017R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11017R
Lokale Artikelnummer::
BOSSBS-11017R
Beschreibung:
Long pentraxins are a family of highly conserved proteins that are expressed in the brain and central nervous system, and form multimeric complexes. Neuronal pentraxin 1 (NP1), NP2, and neuronal pentraxin receptor (NPR) are members of the long pentraxins that represent a neuronal uptake pathway that may function during synapse formation and remodeling. The NP1 gene is located on chromosome 17q25.3 and the protein product mediates the uptake of synaptic material, including the presynaptic snake venom toxin, taipoxin (3). NP2, whose function is unknown, is located on chromosome 7q22.1 and like NP1 contains several potential N-linked glycosylation sites. NPR is expressed on the cell membrane and can form heteropentamers with NP1 and NP2 that can be released from the cell membrane by proteolysis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11674R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11674R
Lokale Artikelnummer::
BOSSBS-11674R
Beschreibung:
Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11695R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11695R-A680
Lokale Artikelnummer::
BOSSBS-11695R-A680
Beschreibung:
The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe²⁺ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.
VE:
1 * 100 µl
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