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Ethyl-2-naphthoyl+formate
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Ethyl-2-naphthoyl+formate
Artikel-Nr:
(BOSSBS-3464R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3464R-CY3
Lokale Artikelnummer::
BOSSBS-3464R-CY3
Beschreibung:
Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3464R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3464R-A750
Lokale Artikelnummer::
BOSSBS-3464R-A750
Beschreibung:
Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3464R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3464R-FITC
Lokale Artikelnummer::
BOSSBS-3464R-FITC
Beschreibung:
Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6473R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6473R-CY3
Lokale Artikelnummer::
BOSSBS-6473R-CY3
Beschreibung:
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:25537362). Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK. DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering. May positively regulate Rho family GTPases through FNTA. Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression. Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1322R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1322R-A750
Lokale Artikelnummer::
BOSSBS-1322R-A750
Beschreibung:
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4054R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4054R-A750
Lokale Artikelnummer::
BOSSBS-4054R-A750
Beschreibung:
S adenosylmethionine synthetase catalyses the formation of S adenosylmethionine from methionine and ATP. In mammalian tissues, there are three distinct forms of AdoMet synthases designated as alpha, beta, and gamma. Alpha and beta are expressed only in adult liver, while gamma is widely distributed in extrahepatic tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4159R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4159R-A680
Lokale Artikelnummer::
BOSSBS-4159R-A680
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7876R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7876R-A680
Lokale Artikelnummer::
BOSSBS-7876R-A680
Beschreibung:
May play a role in fertility and microtubule formation through interaction with RANBP9.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1587R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1587R-A680
Lokale Artikelnummer::
BOSSBS-1587R-A680
Beschreibung:
Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyses the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12243R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12243R-A350
Lokale Artikelnummer::
BOSSBS-12243R-A350
Beschreibung:
Essential for mesoderm formation and axial patterning during embryonic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7872R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7872R-FITC
Lokale Artikelnummer::
BOSSBS-7872R-FITC
Beschreibung:
Involved in epithelial differentiation and contributes to epidermal integrity and barrier formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8291R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8291R-A555
Lokale Artikelnummer::
BOSSBS-8291R-A555
Beschreibung:
Required during spermatogenesis for sperm head elongation and acrosome formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5107R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5107R-FITC
Lokale Artikelnummer::
BOSSBS-5107R-FITC
Beschreibung:
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6425R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6425R-A350
Lokale Artikelnummer::
BOSSBS-6425R-A350
Beschreibung:
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6425R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6425R-A680
Lokale Artikelnummer::
BOSSBS-6425R-A680
Beschreibung:
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13681R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13681R-A350
Lokale Artikelnummer::
BOSSBS-13681R-A350
Beschreibung:
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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