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IGEPAL\\\\\\\\u00AE+CA-630
Artikel-Nr:
(KRAF03632.2000)
Lieferant:
Bernd Kraft
Hersteller-Artikelnummer::
03632.2000
Lokale Artikelnummer::
KRAF03632.2000
Beschreibung:
Calcium Standard, 1000 mg/L, Calcium, Matrix: 0,5 M HNO₃, Anwendung: AAS-Standards
VE:
1 * 500 mL
Artikel-Nr:
(STRE28-0010-2G)
Lieferant:
Strem Chemicals, Inc.
Hersteller-Artikelnummer::
28-0010-2G
Lokale Artikelnummer::
STRE28-0010-2G
Beschreibung:
Bis(1,5-cyclooctadien)nickel(0) ≥98%
VE:
1 * 2 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(HACH2305442)
Lieferant:
Hach
Hersteller-Artikelnummer::
2305442
Lokale Artikelnummer::
HACH2305442
Beschreibung:
ISE-Standards werden zur Kalibrierung von Messsystemen für ionenselektive Elektroden durch Abstimmung des Elektrodenausgangs mit der Konzentration des Analyten verwendet. Für die Analyse werden Paare von Standards mit Konzentrationen, die sich durch einen Faktor von zehn unterscheiden, verwendet.
VE:
1 * 100 mL
Artikel-Nr:
(ABCAAB308174-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB308174-100
Lokale Artikelnummer::
ABCAAB308174-100
Beschreibung:
Anti-Calnexin Rabbit Monoclonal Antibody [clone: HL1598]
VE:
1 * 100 µl
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BSBTPB9989)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PB9989
Lokale Artikelnummer::
BSBTPB9989
Beschreibung:
CA2 is a cytosolic enzyme with the highest activity among all known CAs. The carbonic anhydrases (ACs) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification. This gene is mapped to 8q22.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-1687R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1687R-A647
Lokale Artikelnummer::
BOSSBS-1687R-A647
Beschreibung:
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. Phosphorylates PRKD1 and regulates JNK signaling by binding and activating PRKD1 under oxidative stress. Phosphorylates BECN1, reducing its interaction with BCL2 and BCL2L1 and promoting the induction of autophagy. Phosphorylates TSC2, disrupting the TSC1-TSC2 complex and stimulating mTORC1 activity in a growth factor-dependent pathway. Phosphorylates RPS6, MYL9 and DAPK3. Acts as a signaling amplifier of NMDA receptors at extrasynaptic sites for mediating brain damage in stroke. Cerebral ischemia recruits DAPK1 into the NMDA receptor complex and it phosphorylates GRINB at Ser-133 inducing injurious Ca(2+) influx through NMDA receptor channels, resulting in an irreversible neuronal death. Required together with DAPK3 for phosphorylation of RPL13A upon interferon-gamma activation which is causing RPL13A involvement in transcript-selective translation inhibition. Isoform 2 cannot induce apoptosis but can induce membrane blebbing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1687R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1687R-CY3
Lokale Artikelnummer::
BOSSBS-1687R-CY3
Beschreibung:
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. Phosphorylates PRKD1 and regulates JNK signaling by binding and activating PRKD1 under oxidative stress. Phosphorylates BECN1, reducing its interaction with BCL2 and BCL2L1 and promoting the induction of autophagy. Phosphorylates TSC2, disrupting the TSC1-TSC2 complex and stimulating mTORC1 activity in a growth factor-dependent pathway. Phosphorylates RPS6, MYL9 and DAPK3. Acts as a signaling amplifier of NMDA receptors at extrasynaptic sites for mediating brain damage in stroke. Cerebral ischemia recruits DAPK1 into the NMDA receptor complex and it phosphorylates GRINB at Ser-133 inducing injurious Ca(2+) influx through NMDA receptor channels, resulting in an irreversible neuronal death. Required together with DAPK3 for phosphorylation of RPL13A upon interferon-gamma activation which is causing RPL13A involvement in transcript-selective translation inhibition. Isoform 2 cannot induce apoptosis but can induce membrane blebbing.
VE:
1 * 100 µl
Artikel-Nr:
(506158-10)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
506158-10
Lokale Artikelnummer::
CALB506158-10
Beschreibung:
The p38 MAP Kinase Inhibitor VII, SD-169, also referenced under CAS 1670-87-7, controls the biological activity of p38 MAP Kinase.
VE:
1 * 10 mg
Artikel-Nr:
(PRSI90-137)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-137
Lokale Artikelnummer::
PRSI90-137
Beschreibung:
Calreticulin is involved in regulation of intracellular Ca²⁺ homoeostasis and ER Ca²⁺ capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible for folding and quality control of newly synthesised glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumour cells, increasing phagocytosis.
VE:
1 * 10 µG
Artikel-Nr:
(BOSSBS-3162R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3162R-A555
Lokale Artikelnummer::
BOSSBS-3162R-A555
Beschreibung:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3162R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3162R-CY5
Lokale Artikelnummer::
BOSSBS-3162R-CY5
Beschreibung:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation.
VE:
1 * 100 µl
Artikel-Nr:
(HEWL8500-6940)
Lieferant:
Agilent
Hersteller-Artikelnummer::
8500-6940
Lokale Artikelnummer::
HEWL8500-6940
Beschreibung:
Multi-Element Standard, Multi-element calibration standard-2A, 100 ml, (27 elements in diluted nitric acid) Ag, Al, As, Ba, Be, Ca, Cd, Co, Cr, Cs, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Rb, Se, Sr, Tl, U, V, Zn, 10 mg/L, Matrix: 5% HNO₃, Anwendung: ICP-Standards
VE:
1 * 1 ST
Lieferant:
Corning
Beschreibung:
Spin-X®-Filter für Zentrifugenröhrchen nutzen Zentrifugation zur Entfernung von Bakterien, Partikeln oder Zellen aus Flüssigkeiten, zur HPLC-Probenvorbereitung und zur DNA-Entfernung aus Agarose- oder Acrylamidgelen.
Artikel-Nr:
(PERCN9303825)
Lieferant:
PERKIN ELMER GC INSTRUMENTS
Hersteller-Artikelnummer::
N9303825
Lokale Artikelnummer::
PERCN9303825
Beschreibung:
Multi-Element Standard, Initial calibration verification standard 1, (5% HNO<sub>3</sub>/tr Tartaric Acid), 125 ml, 1000 mg/l: Ca, Fe, K, Mg, Na, Sr and 10 mg/l: Ag, Al, As, Ba, Be, Cd, Co, Cr, Cu, Mn, Mo, Ni, Pb, Sb, Se, Tl, V, Zn, Th, U, Matrix: 5% HNO₃
VE:
1 * 1 ST
Lieferant:
VWR Collection
Beschreibung:
Leichte kostengünstige PP-Kugeln, die die Oberfläche der Flüssigkeit bedecken. Kugeln haben einen Ø von 20 mm, 275 Kugeln bedecken ca. 1000 cm².
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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