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Artikel-Nr: (BOSSBS-11060R-A350)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11060R-A350

Lokale Artikelnummer:: BOSSBS-11060R-A350

Beschreibung: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11060R-FITC)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11060R-FITC

Lokale Artikelnummer:: BOSSBS-11060R-FITC

Beschreibung: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11060R-A750)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11060R-A750

Lokale Artikelnummer:: BOSSBS-11060R-A750

Beschreibung: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11067R-CY3)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11067R-CY3

Lokale Artikelnummer:: BOSSBS-11067R-CY3

Beschreibung: Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.

VE: 1 * 100 µl

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Artikel-Nr: (MANA931301)

Lieferant: MACHEREY-NAGEL

Hersteller-Artikelnummer:: 931301

Lokale Artikelnummer:: MANA931301

Beschreibung: Analysenkoffer sind flexibel einsetzbare Hilfsmittel für alle Anwendungsbereiche der Wasser- und Bodenanalytik. Die Koffer sind ideal für die Kontrolle von Gewässern, für die Fischzucht und viele andere Anwendungen im Bereich des Umweltmanagements und der Wasserüberwachung.

VE: 1 * 1 SET

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Artikel-Nr: (BOSSBS-11060R-A647)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11060R-A647

Lokale Artikelnummer:: BOSSBS-11060R-A647

Beschreibung: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-4065R-A350)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-4065R-A350

Lokale Artikelnummer:: BOSSBS-4065R-A350

Beschreibung: Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-4065R-HRP)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-4065R-HRP

Lokale Artikelnummer:: BOSSBS-4065R-HRP

Beschreibung: Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-4065R-A488)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-4065R-A488

Lokale Artikelnummer:: BOSSBS-4065R-A488

Beschreibung: Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.

VE: 1 * 100 µl

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Artikel-Nr: (VILB141010011)

Lieferant: Vilber Lourmat

Hersteller-Artikelnummer:: 141010011

Lokale Artikelnummer:: VILB141010011

Beschreibung: Bio-1D ist eine professionelle, intuitiv bedienbare Software zur Analyse unterschiedlichster Messdaten des Fluoreszenz-, Bio- und Chemilumineszenz-Imagings. Die Software arbeitet mit DNA, RNA, Proteinen, Polynukleotiden, Petrischalen, Mikroplatten, Pflanzen und <i>in vivo</i>-Darstellungen.

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Artikel-Nr: (521-4174)

Lieferant: BECKMAN COULTER

Hersteller-Artikelnummer:: A47882

Lokale Artikelnummer:: BECMA47882

Beschreibung: The Optima MAX-XP's convenient touch-screen control features easy-to-read displays for gauging real-time speed, time, and temperature. The customisable user interface allows personalisation of easy-to-identify icons for up to twelve individuals, as well as sound and volume options. Multiple language capability: Access to an array of languages increases the Optima MAX-XP's functionality, anywhere in the world. From French and Spanish to Japanese, simplified Chinese and more, the Optima MAX-XP's ability to work in multiple languages enhances its value for laboratories around the world.

VE: 1 * 1 ST

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Artikel-Nr: (BOSSBS-11264R-FITC)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11264R-FITC

Lokale Artikelnummer:: BOSSBS-11264R-FITC

Beschreibung: Myosin VI a molecular motor involved in intracellular vesicle and organelle transport, is the only Myosin motor that binds to the pointed end of Actin. This unique Myosin has only one light chain in the lever-arm domain and has highly irregular stepping with a wide range of step sizes, unlike that of other characterized Myosins. It associates with Clathrin-coated vesicles and disabled 2, indicating a role for Myosin VI in endocytosis. Mouse Myosin VI is expressed within the sensory hair cells of the cochlea. Human Myosin VI is mapped to the centromeric region of chromosome 6, a region that shows syntenic homology with the corresponding mouse chromosome 9 region, where the Snell’s Waltzer mutation is located. The behavioral effects of the mouse Snell’s Waltzer mutation are lack of responsiveness to sound, hyperactivity, head tossing and circling, due to the disorganization and fusing of stereocilia bundles within the inner ear. Defects of Myosin VI cause autosomal dominant nonsyndromic sensori-neural deafness in humans. Human Myosin VI is expressed in fetal cochlea and brain, as well as in adult brain.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11264R-A647)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11264R-A647

Lokale Artikelnummer:: BOSSBS-11264R-A647

Beschreibung: Myosin VI a molecular motor involved in intracellular vesicle and organelle transport, is the only Myosin motor that binds to the pointed end of Actin. This unique Myosin has only one light chain in the lever-arm domain and has highly irregular stepping with a wide range of step sizes, unlike that of other characterized Myosins. It associates with Clathrin-coated vesicles and disabled 2, indicating a role for Myosin VI in endocytosis. Mouse Myosin VI is expressed within the sensory hair cells of the cochlea. Human Myosin VI is mapped to the centromeric region of chromosome 6, a region that shows syntenic homology with the corresponding mouse chromosome 9 region, where the Snell’s Waltzer mutation is located. The behavioral effects of the mouse Snell’s Waltzer mutation are lack of responsiveness to sound, hyperactivity, head tossing and circling, due to the disorganization and fusing of stereocilia bundles within the inner ear. Defects of Myosin VI cause autosomal dominant nonsyndromic sensori-neural deafness in humans. Human Myosin VI is expressed in fetal cochlea and brain, as well as in adult brain.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11264R-CY7)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11264R-CY7

Lokale Artikelnummer:: BOSSBS-11264R-CY7

Beschreibung: Myosin VI a molecular motor involved in intracellular vesicle and organelle transport, is the only Myosin motor that binds to the pointed end of Actin. This unique Myosin has only one light chain in the lever-arm domain and has highly irregular stepping with a wide range of step sizes, unlike that of other characterized Myosins. It associates with Clathrin-coated vesicles and disabled 2, indicating a role for Myosin VI in endocytosis. Mouse Myosin VI is expressed within the sensory hair cells of the cochlea. Human Myosin VI is mapped to the centromeric region of chromosome 6, a region that shows syntenic homology with the corresponding mouse chromosome 9 region, where the Snell’s Waltzer mutation is located. The behavioral effects of the mouse Snell’s Waltzer mutation are lack of responsiveness to sound, hyperactivity, head tossing and circling, due to the disorganization and fusing of stereocilia bundles within the inner ear. Defects of Myosin VI cause autosomal dominant nonsyndromic sensori-neural deafness in humans. Human Myosin VI is expressed in fetal cochlea and brain, as well as in adult brain.

VE: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-11060R-CY5)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11060R-CY5

Lokale Artikelnummer:: BOSSBS-11060R-CY5

Beschreibung: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.

VE: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-11060R-CY3)

Lieferant: Bioss

Hersteller-Artikelnummer:: BS-11060R-CY3

Lokale Artikelnummer:: BOSSBS-11060R-CY3

Beschreibung: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.

VE: 1 * 100 µl

Sale