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6-Bromo-7-fluorobenzo[b]thiophene
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6-Bromo-7-fluorobenzo[b]thiophene
Artikel-Nr:
(BOSSBS-10501R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10501R-CY3
Lokale Artikelnummer::
BOSSBS-10501R-CY3
Beschreibung:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1238R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1238R-CY5.5
Lokale Artikelnummer::
BOSSBS-1238R-CY5.5
Beschreibung:
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Used in the determination of protein concentration. Proteins reduce alkaline Cu(II) to Cu(I) which complexes with BCA to form a purple complex. Absorbance at 562nm is directly proportional to protein concentration.
Artikel-Nr:
(705-0867)
Lieferant:
Hach
Hersteller-Artikelnummer::
4942500
Lokale Artikelnummer::
HACH4942500
Beschreibung:
Instrumentenkoffer, hartwandig, Form G
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-11103R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11103R-HRP
Lokale Artikelnummer::
BOSSBS-11103R-HRP
Beschreibung:
Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin-1, which is the mammalian homolog of UNC-6 from C. elegans, is largely expressed in the developing nervous system and in mesodermal tissues. Netrin-1 is expressed by the floor plate as either a cell associated protein or in a diffusible form, and it binds to several surface receptor components, including deleted in colorectal cancer (DCC) and neogenin. During embryonic development, netrin-1 diffuses through the neuronal epithelium, where it forms a chemoattractant gradient that directs axonal migration to the ventral midline of the spinal cord. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins, as the cells are repelled, rather than attracted, by the netrin gradient.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1347R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1347R-CY5.5
Lokale Artikelnummer::
BOSSBS-1347R-CY5.5
Beschreibung:
Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1347R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1347R-CY5
Lokale Artikelnummer::
BOSSBS-1347R-CY5
Beschreibung:
Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9443R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9443R-CY3
Lokale Artikelnummer::
BOSSBS-9443R-CY3
Beschreibung:
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9443R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9443R-CY5.5
Lokale Artikelnummer::
BOSSBS-9443R-CY5.5
Beschreibung:
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10151R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10151R-A647
Lokale Artikelnummer::
BOSSBS-10151R-A647
Beschreibung:
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus. Interacts with, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins. Involved in HTLV-1 Rex multimerization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3195R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3195R-A647
Lokale Artikelnummer::
BOSSBS-3195R-A647
Beschreibung:
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, is phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes. Can activate distinct gene expression programs in macrophages and can induce significant apoptosis in primary macrophages.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Provides a source of iron used in cell culture applications. Provides iron in a less toxic form than free iron salts.
Artikel-Nr:
(BOSSBS-1212R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1212R-A350
Lokale Artikelnummer::
BOSSBS-1212R-A350
Beschreibung:
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0654R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0654R-HRP
Lokale Artikelnummer::
BOSSBS-0654R-HRP
Beschreibung:
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6688R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6688R-FITC
Lokale Artikelnummer::
BOSSBS-6688R-FITC
Beschreibung:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11672R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11672R
Lokale Artikelnummer::
BOSSBS-11672R
Beschreibung:
The intronless STH gene lies between exons 9 and 10 of the tau gene, which is implicated in a number of neurodegenerative disorders. It encodes a 128 residue protein with no clear homologs, and mimics the expresison patterns of tau. Though a polymorphism (Q7R) appears significant, data does not clearly show thus far whether or not this phenotype provides a useful marker for Alzheimer’s or other forms of neurodegenerative disease.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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