L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-3733R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3733R-CY7
Lokale Artikelnummer::
BOSSBS-3733R-CY7
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3123R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3123R-CY7
Lokale Artikelnummer::
BOSSBS-3123R-CY7
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3406R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3406R-CY7
Lokale Artikelnummer::
BOSSBS-3406R-CY7
Beschreibung:
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromosome proteins are conserved in eukaryotes and can lead to mitotic chromosome segregation defects, suggesting a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. A number of cellular factors interact with hSMC1/hSMC3 during cell cycle. The major population of hSMC1/hSMC3 is in a compex with hRAD21 forming the human cohesion complex. Human cohesion complex associates with chromosomes which peaks at S phase and dissociates from chromosomes during G2/M transition. In addition, a subpopulation of hSMC1/hSMC3 associates tightly with nuclear matrix and centrosomes during interphase. A subset of hSMC1/hSMC3 is localized to spindle poles, spindles and kinetochores during mitosis when cohesin is in the cytoplasm. hSMC1/hSMC3 is required for spindle aster formation in vitro and reacts with nuclear mitotic apparatus protein in vivo.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4846R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4846R-CY5
Lokale Artikelnummer::
BOSSBS-4846R-CY5
Beschreibung:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
VE:
1 * 100 µl
Lieferant:
Tonbo Biosciences
Beschreibung:
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
Artikel-Nr:
(BOSSBS-1324R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1324R-CY5.5
Lokale Artikelnummer::
BOSSBS-1324R-CY5.5
Beschreibung:
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils (PubMed:1679162, PubMed:13864, PubMed:8525373, PubMed:9516414, PubMed:15923218). May also be an agonist of the G protein-coupled receptor GPR75, stimulating inositol trisphosphate production and calcium mobilization through its activation. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed:23979485).
VE:
1 * 100 µl
Artikel-Nr:
(90010.)
Lieferant:
Biotium
Hersteller-Artikelnummer::
90010
Lokale Artikelnummer::
BTIU90010
Beschreibung:
ANTS (8-aminonaphthalene-1,3,6-trisulfonic acid, disodium salt) is a highly negatively charged dye with an amino group that can be coupled to an aldehyde or ketone group to form an unstable Schiff base. The Schiff base is usually chemically reduced by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaB(CN)H3) to form a stable linkage. This labeling technique has been widely used for the labeling and subsequent sequencing of oligosaccharides and glycoproteins. The negative charges of the dye facilitate the electrophoretic separation of the degradation products of carbohydrate polymers.
VE:
1 * 500 mg
Artikel-Nr:
(BOSSBS-2963R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2963R-A350
Lokale Artikelnummer::
BOSSBS-2963R-A350
Beschreibung:
This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7718R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7718R-A555
Lokale Artikelnummer::
BOSSBS-7718R-A555
Beschreibung:
CAPD2 is a regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condensed chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. It may target the condensin complex to DNA via its C-terminal domain (referenced from Swissprot).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2963R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2963R-FITC
Lokale Artikelnummer::
BOSSBS-2963R-FITC
Beschreibung:
This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5328R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5328R-HRP
Lokale Artikelnummer::
BOSSBS-5328R-HRP
Beschreibung:
HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6674R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6674R-CY5.5
Lokale Artikelnummer::
BOSSBS-6674R-CY5.5
Beschreibung:
KCNK3 encodes one of the members of the superfamily of potassium channel proteins containing two pore forming P domains. The gene product is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2686R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2686R-CY3
Lokale Artikelnummer::
BOSSBS-2686R-CY3
Beschreibung:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7586R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7586R
Lokale Artikelnummer::
BOSSBS-7586R
Beschreibung:
The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10369R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10369R
Lokale Artikelnummer::
BOSSBS-10369R
Beschreibung:
The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012].
VE:
1 * 100 µl
Lieferant:
Tonbo Biosciences
Beschreibung:
The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.
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