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N-Methyl-N-[2-(4-methylphenoxy)benzyl]amine
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N-Methyl-N-[2-(4-methylphenoxy)benzyl]amine
Artikel-Nr:
(BOSSBS-5204R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5204R-A555
Lokale Artikelnummer::
BOSSBS-5204R-A555
Beschreibung:
E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1160R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1160R-CY7
Lokale Artikelnummer::
BOSSBS-1160R-CY7
Beschreibung:
Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3521R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3521R-CY5
Lokale Artikelnummer::
BOSSBS-3521R-CY5
Beschreibung:
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5983R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5983R-CY5
Lokale Artikelnummer::
BOSSBS-5983R-CY5
Beschreibung:
AARE (Acylamino-acid-releasing enzyme) is also known as Acyl-peptide hydrolase. It catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus corresponding to the protein are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5983R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5983R-CY5.5
Lokale Artikelnummer::
BOSSBS-5983R-CY5.5
Beschreibung:
AARE (Acylamino-acid-releasing enzyme) is also known as Acyl-peptide hydrolase. It catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus corresponding to the protein are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6765R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6765R-CY5
Lokale Artikelnummer::
BOSSBS-6765R-CY5
Beschreibung:
Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6765R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6765R-CY7
Lokale Artikelnummer::
BOSSBS-6765R-CY7
Beschreibung:
Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5661R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5661R-A750
Lokale Artikelnummer::
BOSSBS-5661R-A750
Beschreibung:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3793R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3793R-A488
Lokale Artikelnummer::
BOSSBS-3793R-A488
Beschreibung:
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi apparatus but which can be proteolytically processed to a soluble form, is involved in the generation of the cell surface carbohydrate determinants and differentiation antigens HB6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5094R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5094R-FITC
Lokale Artikelnummer::
BOSSBS-5094R-FITC
Beschreibung:
UROD is the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria. Porphyria cutanea tarda is an autosomal dominant disorder characterized by light-sensitive dermatitis and associated with the excretion of large amounts of uroporphyrin in urine. Hepatoerythropoetic porphyria is a form of porphyria cutanae tarda that may also be a manifestation of benign or malignant hepatic tumors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2595R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2595R-A750
Lokale Artikelnummer::
BOSSBS-2595R-A750
Beschreibung:
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralisation of IL1B by secreted/soluble receptors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3950R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3950R-A647
Lokale Artikelnummer::
BOSSBS-3950R-A647
Beschreibung:
The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5336R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5336R-A555
Lokale Artikelnummer::
BOSSBS-5336R-A555
Beschreibung:
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1350R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-CY5
Lokale Artikelnummer::
BOSSBS-1350R-CY5
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1350R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-FITC
Lokale Artikelnummer::
BOSSBS-1350R-FITC
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5983R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5983R-HRP
Lokale Artikelnummer::
BOSSBS-5983R-HRP
Beschreibung:
AARE (Acylamino-acid-releasing enzyme) is also known as Acyl-peptide hydrolase. It catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus corresponding to the protein are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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