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4-Amino-1,5-dimethylimidazole+hydrochloride
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4-Amino-1,5-dimethylimidazole+hydrochloride
Artikel-Nr:
(BOSSBS-3400R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3400R-A488
Lokale Artikelnummer::
BOSSBS-3400R-A488
Beschreibung:
Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC. May inhibit differentiation and activity of osteoprogenitor cells. Functions in signaling downstream of integrin and collagen receptors, immune receptors, G-protein coupled receptors (GPCR), cytokine, chemokine and growth factor receptors, and mediates responses to cellular stress. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Regulates production of the cellular messenger cGMP. Promotes activation of the MAP kinase signaling cascade, including activation of MAPK1/ERK2, MAPK3/ERK1 and MAPK8/JNK1. Promotes activation of Rho family GTPases, such as RHOA and RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Acts as a scaffold, binding to both PDPK1 and SRC, thereby allowing SRC to phosphorylate PDPK1 at 'Tyr-9, 'Tyr-373', and 'Tyr-376'. Promotes phosphorylation of NMDA receptors by SRC family members, and thereby contributes to the regulation of NMDA receptor ion channel activity and intracellular Ca(2+) levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3400R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3400R-A680
Lokale Artikelnummer::
BOSSBS-3400R-A680
Beschreibung:
Non-receptor protein-tyrosine kinase that regulates reorganisation of the actin cytoskeleton, cell polarisation, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarisation and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC. May inhibit differentiation and activity of osteoprogenitor cells. Functions in signaling downstream of integrin and collagen receptors, immune receptors, G-protein coupled receptors (GPCR), cytokine, chemokine and growth factor receptors, and mediates responses to cellular stress. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Regulates production of the cellular messenger cGMP. Promotes activation of the MAP kinase signaling cascade, including activation of MAPK1/ERK2, MAPK3/ERK1 and MAPK8/JNK1. Promotes activation of Rho family GTPases, such as RHOA and RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Acts as a scaffold, binding to both PDPK1 and SRC, thereby allowing SRC to phosphorylate PDPK1 at 'Tyr-9, 'Tyr-373', and 'Tyr-376'. Promotes phosphorylation of NMDA receptors by SRC family members, and thereby contributes to the regulation of NMDA receptor ion channel activity and intracellular Ca(2+) levels. .
VE:
1 * 100 µl
Artikel-Nr:
(HACH2448700)
Lieferant:
Hach
Hersteller-Artikelnummer::
2448700
Lokale Artikelnummer::
HACH2448700
Beschreibung:
For sequential determination of calcium and total hardness by EDTA digital titrator titration.
VE:
1 * 1 KIT
Artikel-Nr:
(BOSSBS-3400R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3400R-A647
Lokale Artikelnummer::
BOSSBS-3400R-A647
Beschreibung:
Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC. May inhibit differentiation and activity of osteoprogenitor cells. Functions in signaling downstream of integrin and collagen receptors, immune receptors, G-protein coupled receptors (GPCR), cytokine, chemokine and growth factor receptors, and mediates responses to cellular stress. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Regulates production of the cellular messenger cGMP. Promotes activation of the MAP kinase signaling cascade, including activation of MAPK1/ERK2, MAPK3/ERK1 and MAPK8/JNK1. Promotes activation of Rho family GTPases, such as RHOA and RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Acts as a scaffold, binding to both PDPK1 and SRC, thereby allowing SRC to phosphorylate PDPK1 at 'Tyr-9, 'Tyr-373', and 'Tyr-376'. Promotes phosphorylation of NMDA receptors by SRC family members, and thereby contributes to the regulation of NMDA receptor ion channel activity and intracellular Ca(2+) levels.
VE:
1 * 100 µl
Lieferant:
LGC Standards PROMOCHEM
Beschreibung:
The solutions are intended for use as a certified reference material or calibration standard for the analysis of these elements in petroleum products or other organic matrices using inductively coupled plasma optical emission spectroscopy (ICP-OES), inductively coupled plasma mass spectrometry (ICP-MS), rotating disc electrode atomic emission spectroscopy (RDE-AES), flame or furnace atomic absorption spectroscopy (AA or GFAA), and other techniques for elemental analysis.
Lieferant:
Agilent
Beschreibung:
<B>Sicherheitshinweis: </B>Diese Standards sind in Säurelösung. Genaue Angaben zu Gefahren und Spezifikationen finden Sie unter www.vwr.com. Dort finden Sie auch Links zu den Materialsicherheitsdatenblättern (MSDS) und den technischen Datenblättern
Artikel-Nr:
(PRSI91-095)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-095
Lokale Artikelnummer::
PRSI91-095
Beschreibung:
Carbonic Anhydrase 8 (CA8) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Because CA8 has some sequence similarity with other known carbonic anhydrase genes, it was firstly called as CA-related protein. Nevertheless, CA8 does not have a carbonic anhydrase catalytic activity. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3), which is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation.
VE:
1 * 50 µG
Artikel-Nr:
(903-0563)
Lieferant:
VWR Collection
Lokale Artikelnummer::
HITA892-0163
Beschreibung:
Chromaster HPLC integrierte Minipumpe speziell zum Waschen des Kolbens der Chromaster HPLC 5110 und 5160 Pumpen, Wird bei Verwendung von hohen Anteilen an anorganischen Phasenmodifizierern wie z. B. Phosphatpuffern empfohlen
VE:
1 * 1 ST
Lieferant:
Bel-Art Products, a Part of SP
Beschreibung:
These wash bottles, made of LDPE, translucent, with PP spray cup feature a 53 mm wide mouth for easy refilling and are pre-printed with the chemical name and formula, the National Fire Protection Association (NFPA) section 704 four-colour diamond, health hazards, Chemical Abstract System (CAS) number and suggested protective clothing and equipment. Leak-proof, these bottles have PP polypropylene closures to aid in quick and easy identification.
Artikel-Nr:
(511071-2)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
511071-2
Lokale Artikelnummer::
CALB511071-2
Beschreibung:
The PAF Receptor Antagonist, ABT-491, also referenced under CAS 189689-94-9, controls the biological activity of PAF Receptor. This small molecule/inhibitor is primarily used for Membrane applications.
VE:
1 * 2 mg
Artikel-Nr:
(PRSI91-285)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-285
Lokale Artikelnummer::
PRSI91-285
Beschreibung:
Carbonic Anhydrase X (CA10) belongs to CA family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes such as respiration, renal tubular acidification and bone resorption. While CA10 is a secreted protein without Carbonic Anhydrase activity (i.e., the reversible hydration of CO2) due to point mutations in the zinc binding site, it has esterase activity. The human and mouse CA10 are expressed in the brain, indicating that they may play a role in brain development.
VE:
1 * 50 µG
Lieferant:
Lovibond Tintometer
Beschreibung:
Sauerstoffsensor, mit ca. 4-m-Kabel, Für: Multi-parameter meters SensoDirect 150
Lieferant:
Abcam
Beschreibung:
Anti-Caspase-10/CASP-10 Rabbit Monoclonal Antibody [clone: EPR10890]
Artikel-Nr:
(PRSI28-512)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-512
Lokale Artikelnummer::
PRSI28-512
Beschreibung:
ANXA1 encodes a protein that belongs to a family of Ca (2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
VE:
1 * 100 µG
Lieferant:
VARIAN
Beschreibung:
Hi-Plex HPLC columns deliver improved efficiency, lower operating pressures and longer column lifetimes from monodispersed materials. With a range of ligand counter ions for optimum selectivity and resolution and materials matched to the USP definitions of media types L17, L19, L34 and L58, the Hi-Plex range is ideal for isocratic separations using water or dilute acid as the eluent. This simplifies your HPLC system requirements and eliminates the use of potentially hazardous organic solvents.
Artikel-Nr:
(PRSIXW-RP3028)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-RP3028
Lokale Artikelnummer::
PRSIXW-RP3028
Beschreibung:
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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