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cis-2-Benzylamino-cyclohexanol+hydrochloride
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cis-2-Benzylamino-cyclohexanol+hydrochloride
Artikel-Nr:
(PRSI90-480)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-480
Lokale Artikelnummer::
PRSI90-480
Beschreibung:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1 and IL-6 by macrophages.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI90-468)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-468
Lokale Artikelnummer::
PRSI90-468
Beschreibung:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI91-540)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-540
Lokale Artikelnummer::
PRSI91-540
Beschreibung:
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms ( alpha, beta , gamma , and delta) with identical extracellular domains.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI77-175)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-175
Lokale Artikelnummer::
PRSI77-175
Beschreibung:
The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro/in vivo.
VE:
1 * 0,5 mg
New Product
Artikel-Nr:
(PRSI76-505)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-505
Lokale Artikelnummer::
PRSI76-505
Beschreibung:
The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor alpha (IL-2R alpha, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor beta chain (CD122) and the common gamma chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.
VE:
1 * 25 Tests
New Product
Artikel-Nr:
(PRSI76-500)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-500
Lokale Artikelnummer::
PRSI76-500
Beschreibung:
The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor alpha (IL-2R alpha, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor beta chain (CD122) and the common gamma chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(PRSI2499)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2499
Lokale Artikelnummer::
PRSI2499
Beschreibung:
CIKS Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappa B associates with I kappa B proteins in the cell cytoplasm, which inhibit NF-kappa B activity. I kappa B is phosphorylated by I kappa B kinase (IKK) complex that contains IKK alpha , IKK beta , and IKK gamma. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kappa B activator 1). CIKS directly interacts with IKK gamma. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI76-502)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-502
Lokale Artikelnummer::
PRSI76-502
Beschreibung:
The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor alpha (IL-2R alpha, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor beta chain (CD122) and the common gamma chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(APOSBICL4374-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BICL4374-1G
Lokale Artikelnummer::
APOSBICL4374-1G
Beschreibung:
3,4,6-Tri-O-acetyl-1,2-O-(1-methoxyethylidene)-β-D-mannopyranose ≥98%
VE:
1 * 1 g
Lieferant:
Thermo Scientific
Beschreibung:
Methylcrotonat 96%
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Fluorescein isothiocyanate (FITC) is yellow-orange in color with an absorption maximum at 495nm. Upon excitation, it emits a yellow-green color with an emission maximum at 525 nm. It is widely used to attach a fluorescent label to proteins via the amine group. The isothiocyanate group reacts with amino terminal and primary amines in proteins. It has been used for the labeling of proteins including antibodies and lectins. Fluorescein isothiocyanate isomer I has been proposed as a contact sensitiser.
Artikel-Nr:
(PRSI33-622)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-622
Lokale Artikelnummer::
PRSI33-622
Beschreibung:
Beta Catenin is a dual function protein, regulating the coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. b-Catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to gamma-Catenin, also known as plakoglobin. b-Catenin is widely expressed in many tissues. In cardiac muscle, it localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocyte. [Wiki].
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI92-364)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-364
Lokale Artikelnummer::
PRSI92-364
Beschreibung:
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-475)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-475
Lokale Artikelnummer::
PRSI90-475
Beschreibung:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-530)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-530
Lokale Artikelnummer::
PRSI92-530
Beschreibung:
Interleukin 15 Receptor alpha (IL-15R alpha) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15R alpha chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15R alpha can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15R alpha complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor beta and gamma heterodimers and enables signalling to cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-481)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-481
Lokale Artikelnummer::
PRSI90-481
Beschreibung:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1 and IL-6 by macrophages.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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