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3-(Phenylthio)thiophene
Artikel-Nr:
(BOSSBS-11860R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11860R-A680
Lokale Artikelnummer::
BOSSBS-11860R-A680
Beschreibung:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation Signalling.
VE:
1 * 100 µl
Artikel-Nr:
(ABNOMAB15452)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB15452
Lokale Artikelnummer::
ABNOMAB15452
Beschreibung:
Mouse monoclonal antibody raised against native mouse H2-D1.
VE:
1 * 100 µG
Artikel-Nr:
(CAYM500380-480)
Lieferant:
Cayman Chemical
Hersteller-Artikelnummer::
500380-480
Lokale Artikelnummer::
CAYM500380-480
Beschreibung:
For the quantification of RvD1.
VE:
1 * 480 Tests
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-S100A4 Mouse Monoclonal Antibody [clone: NJ-4F3-D1] (APC (Allophycocyanin))
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-S100A4 Mouse Monoclonal Antibody [clone: NJ-4F3-D1] (FITC (Fluorescein Isothiocyanate))
Artikel-Nr:
(BOSSBS-6992R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6992R-CY3
Lokale Artikelnummer::
BOSSBS-6992R-CY3
Beschreibung:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6992R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6992R-CY7
Lokale Artikelnummer::
BOSSBS-6992R-CY7
Beschreibung:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10.
VE:
1 * 100 µl
Artikel-Nr:
(USBI125491)
Lieferant:
US Biological
Hersteller-Artikelnummer::
125491
Lokale Artikelnummer::
USBI125491
Beschreibung:
Anti-CX3CL1 Mouse Monoclonal Antibody [clone: 1D6]
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-460)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-460
Lokale Artikelnummer::
PRSI33-460
Beschreibung:
Recognises a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
VE:
1 * 100 µG
New Product
Lieferant:
IMMUNOLOGIC
Beschreibung:
Anti-STAT6 Mouse Monoclonal Antibody [clone: D1]
Artikel-Nr:
(BLEG681902)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
681902
Lokale Artikelnummer::
BLEG681902
Beschreibung:
Anti-Cyclin D1 Mouse Monoclonal Antibody [clone: DCS-6]
VE:
1 * 100 µG
 This is a MarketSource item. Additional charges may apply
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-Dopamine Receptor D1 Mouse Monoclonal Antibody [clone: A17050E]
Artikel-Nr:
(BOSSBS-6992R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6992R-CY5
Lokale Artikelnummer::
BOSSBS-6992R-CY5
Beschreibung:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10.
VE:
1 * 100 µl
Artikel-Nr:
(ABNOMAB15446)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB15446
Lokale Artikelnummer::
ABNOMAB15446
Beschreibung:
Mouse monoclonal antibody raised against native mouse H2-D1.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-11234R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11234R
Lokale Artikelnummer::
BOSSBS-11234R
Beschreibung:
The Myc family, including c-Myc-, N-Myc- and L-Myc, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, differentiation, apoptosis and transformation. The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, including Max and Mxi 1; however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression. A POZ domain Zn finger protein, designated Miz-1 for Myc-interacting Zn finger protein-1, is a specific target of Myc-induced gene repression. Miz-1 interacts with Myc, but not Max or other Myc partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1. Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters. Expression of Miz-1 induces potent growth arrest function, and this latency is reversed by the addition of Myc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11860R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11860R
Lokale Artikelnummer::
BOSSBS-11860R
Beschreibung:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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