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5-(3-Chlorophenyl)-3-hydroxypicolinic+acid
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5-(3-Chlorophenyl)-3-hydroxypicolinic+acid
Artikel-Nr:
(ABCAAB183214-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB183214-100
Lokale Artikelnummer::
ABCAAB183214-100
Beschreibung:
Anti-beta 2 Defensin/BD-2 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-4760R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4760R
Lokale Artikelnummer::
BOSSBS-4760R
Beschreibung:
Uteroglobin belongs to the family of secretoglobins and is a secreted protein product of nonciliated bronchiolar Clara cells. There is convincing data suggesting it has phospholipase A2 inhibitory activity, as well as, a number of other immunomodulatory features including inhibition of interferon gamma signalling and Th1 vs. Th2 lymphocyte regulation. It was proposed as a potential peripheral marker of respiratory epithelial injury and bronchial dysfunction. Clara Cell Protein 16 concentrations have been determined in both serum and bronchoalveolar lavage fluid in numerous studies since 1994. In serum, its increase is associated with age, asbestos, nitrogen chloride and ozone exposure, sarcoidosis and high PEEP ventilation. Decreased serum CC16 levels are found after pulmonary resection, in silica-exposed workers, smokers and in asthma. Decreased CC16 concentrations were also found in the amniotic fluid of fetuses suffering from pulmonary hypoplasia caused by various mechanisms (diaphragmatic hernia, diabetic fetopathy, Turner and Down syndrome). In pleural effusions, the CC16 concentration appears to be associated with its diffusion from the lung as evidenced by high CC16 levels in cardiac pleural congestion.
VE:
1 * 100 µl
Artikel-Nr:
(8.41747.0001)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.41747.0001
Lokale Artikelnummer::
MERC8.41747.0001
Beschreibung:
(2-Nitrophenyl)-β-D-galactopyranosid (ONPG) zur Synthese, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-1910R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1910R-A488
Lokale Artikelnummer::
BOSSBS-1910R-A488
Beschreibung:
Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10463R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10463R
Lokale Artikelnummer::
BOSSBS-10463R
Beschreibung:
Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13317R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13317R-CY3
Lokale Artikelnummer::
BOSSBS-13317R-CY3
Beschreibung:
2010013H22Rik; 2210021I22Rik; 2210401J11Rik; 3-galactosyl-O-glycosyl-glycoprotein beta-1; 6-N-acetylglucosaminyltransferase 3; 6-N-acetylglucosaminyltransferase; Beta 1 3 galactosyl O glycosyl glycoprotein beta 1 6 N acetylglucosaminyltransferase 3; Beta-1; Beta1 6 N acetylglucosaminyltransferase 3; beta1 6 N acetylglucosaminyltransferase; C2/4GnT; C24GNT; C2GnT M; C2GnT mucin type; C2GnT-M; C2GnT-mucin type; C2GnT2; C2GNTM; Core 2 beta 1 6 N acetylglucosaminyltransferase II; Core 2/core 4 beta 1 6 N acetylglucosaminyltransferase; Core 2/core 4 beta-1; dI/C2/C4GnT; EC 2.4.1.102; EC 2.4.1.150; GCNT3; GCNT3_HUMAN; Glucosaminyl (N acetyl) transferase 3; Glucosaminyl (N acetyl) transferase 3 mucin type; GnT M; GNTM; hC2GnT M; hC2GnT-M; Mucus-type core 2 beta-1,6-N-acetylglucosaminyltransferase. OTTHUMP00000163601.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10463R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10463R-CY5
Lokale Artikelnummer::
BOSSBS-10463R-CY5
Beschreibung:
Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(PRSI91-208)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-208
Lokale Artikelnummer::
PRSI91-208
Beschreibung:
Gamma-Glutamylaminecyclotransferase is an enzyme that converts gamma-glutamylamines to free amines and 5-oxoproline which belongs to the gamma-glutamylcyclotransferase family. It shows high activity toward gamma-glutamyl-epsilon-lysine, derived from the breakdown of fibrin and contributes to degradation of proteins cross-linked by transglutaminases. It degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. This protein adopts the newly identified cyclotransferase fold, observed in Gamma-Glutamylcyclotransferase, an enzyme with activity toward gamma-glutamyl-alpha-amino acids.
VE:
1 * 50 µG
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-IFN-gamma Mouse Monoclonal Antibody [clone: NIB42] (Ultra-LEAF™)
Artikel-Nr:
(ABCAAB95647-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB95647-100
Lokale Artikelnummer::
ABCAAB95647-100
Beschreibung:
Anti-TCR alpha + TCR beta Mouse Monoclonal Antibody (Biotin) [clone: IP26]
VE:
1 * 100 µG
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(ABCAAB99857-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB99857-100
Lokale Artikelnummer::
ABCAAB99857-100
Beschreibung:
Anti-TCR alpha + TCR beta Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: IP26]
VE:
1 * 100 Tests
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-5791R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5791R-A680
Lokale Artikelnummer::
BOSSBS-5791R-A680
Beschreibung:
Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.
VE:
1 * 100 µl
Artikel-Nr:
(BLEG308611)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
308611
Lokale Artikelnummer::
BLEG308611
Beschreibung:
Anti-CD119 (IFN-gamma R alpha chain) Mouse Monoclonal Antibody [clone: GIR-208] (TotalSeq™-B0219)
VE:
1 * 10 µG
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BLEG308607)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
308607
Lokale Artikelnummer::
BLEG308607
Beschreibung:
Anti-CD119 (IFN-gamma R alpha chain) Mouse Monoclonal Antibody [clone: GIR-208] (TotalSeq™-A0219)
VE:
1 * 10 µG
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-0100R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0100R-A555
Lokale Artikelnummer::
BOSSBS-0100R-A555
Beschreibung:
Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0100R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0100R-HRP
Lokale Artikelnummer::
BOSSBS-0100R-HRP
Beschreibung:
Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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