5-(tert-Butyldimethylsilyloxy)-2-fluorphenylboronsäure
Artikel-Nr:
(BOSSBS-3531R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3531R-CY7
Lokale Artikelnummer::
BOSSBS-3531R-CY7
Beschreibung:
Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, differentiation, development, migration, cell cell adhesion, cell extracellular matrix adhesion, and solute transport. The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1). This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3728R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3728R-A350
Lokale Artikelnummer::
BOSSBS-3728R-A350
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(D8536-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
D8536-5G
Lokale Artikelnummer::
SUPLD8536-5G
Beschreibung:
Organic Standard, Diperodon hydrochloride
VE:
1 * 5 g
Lieferant:
VWR Chemicals
Beschreibung:
di-Natriumhydrogenphosphat Dodecahydrat ≥98%, gereinigt
Artikel-Nr:
(BOSSBS-9575R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9575R-A647
Lokale Artikelnummer::
BOSSBS-9575R-A647
Beschreibung:
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the β-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9575R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9575R-A555
Lokale Artikelnummer::
BOSSBS-9575R-A555
Beschreibung:
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the β-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.
VE:
1 * 100 µl
Lieferant:
Avantor
Beschreibung:
di-Kaliumhydrogenphosphat 98,0-100,5% (Trockenmasse) USP, ACS, J.T.Baker®
Artikel-Nr:
(BOSSBS-12491R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12491R-CY5
Lokale Artikelnummer::
BOSSBS-12491R-CY5
Beschreibung:
Apolipoproteins are protein components of plasma lipoproteins. Apolipoprotein A-I (ApoA1) promotes cholesterol efflux from tissues to the liver for excretion. ApoA1 is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase, which is responsible for the formation of most plasma cholesteryl esters. AI-BP (Apolipoprotein A-I-binding protein), also known as YjeF N-terminal domain-containing protein 1, is a 288 amino acid secreted protein that binds ApoA1, ApoA2 and HDL. Individuals with impaired renal function show an increased rate of AI-BP excretion, indicating that it is normally reabsorbed within the kidney tubules. AI-BP belongs to the YjeF N-terminal domain protein family, which includes proteins that are frequently involved in oogenesis and spermatogenesis. There are two isoforms of AI-BP that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12491R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12491R-CY7
Lokale Artikelnummer::
BOSSBS-12491R-CY7
Beschreibung:
Apolipoproteins are protein components of plasma lipoproteins. Apolipoprotein A-I (ApoA1) promotes cholesterol efflux from tissues to the liver for excretion. ApoA1 is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase, which is responsible for the formation of most plasma cholesteryl esters. AI-BP (Apolipoprotein A-I-binding protein), also known as YjeF N-terminal domain-containing protein 1, is a 288 amino acid secreted protein that binds ApoA1, ApoA2 and HDL. Individuals with impaired renal function show an increased rate of AI-BP excretion, indicating that it is normally reabsorbed within the kidney tubules. AI-BP belongs to the YjeF N-terminal domain protein family, which includes proteins that are frequently involved in oogenesis and spermatogenesis. There are two isoforms of AI-BP that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Artikel-Nr:
(BOSSBS-6546R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6546R
Lokale Artikelnummer::
BOSSBS-6546R
Beschreibung:
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.
VE:
1 * 100 µl
Lieferant:
VWR Collection
Beschreibung:
Nylon, glasfaserverstärkt
Lieferant:
Thermo Scientific
Beschreibung:
Natriumborhydrid 12% in wässriger Lösung, VenPure™, rein
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Phenolphthalein is an acid base indicator. It is a weak acid, which is colorless in acidic solution and turns puce pink in alkaline solution. Phenolphthalein is genotoxic. It might cause oxidative damage and binds to estrogen receptors. Phenolphthalein solution is a synthetic indicator. It is colorless in acidic and neutral conditions. Phenolphthalein gives pink color when added to a base, therefore it is considered as a base indicator.
Artikel-Nr:
(PIER46406)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
46406
Lokale Artikelnummer::
PIER46406
Beschreibung:
NHS-rhodamine is a high performance derivative of rhodamine dye, activated for an amine-specific labelling of antibodies, proteins and other molecules.
VE:
1 * 25 mg
Artikel-Nr:
(BOSSBS-8414R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8414R-A680
Lokale Artikelnummer::
BOSSBS-8414R-A680
Beschreibung:
The hydroxyacylglutathione hydrolase-like protein (HAGHL) is a 290 amino acid protein that belongs to the glyoxalase II family. HAGHL binds two zinc ions per subunit and acts as a hydrolase on ester bonds. The gene encoding HAGHL maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
VE:
1 * 100 µl
Preis auf Anfrage
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