EDTA+disodium+salt+solution+with+zinc+complex+added+(solution+B)
Artikel-Nr:
(BOSSBS-0874R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0874R-A680
Lokale Artikelnummer::
BOSSBS-0874R-A680
Beschreibung:
The DEK gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA which then induces positive supercoils into closed circular DNA, and is also involved during mRNA processing in splice site selection. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2485R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2485R-A680
Lokale Artikelnummer::
BOSSBS-2485R-A680
Beschreibung:
JAK2 (Janus Activating Kinase 2) is a tyrosine kinase of the non-receptor type, that associates with the intracellular domains of cytokine receptors; JAK2 is the predominant JAK kinase activated in response to several growth factors and cytokines such as IL-3, GM-CSF and erythropoietin; it has been found to be constitutively associated with the prolactin receptor and is required for responses to gamma interferon. Ligand binding to a variety of cell surface receptors (e.g., cytokine, growth factor, GPCRs) leads to an association of those receptors with JAK proteins, which are then activated via phosphorylation on tyrosines 1007 and 1008 in the kinase activation loop. Activated JAK proteins phosphorylate and activate STAT (signal transducers and activators of transcription) proteins, which then dimerize and translocate to the nucleus. Once in the nucleus, STAT proteins bind to DNA and modify the transcription of various genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5499R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5499R
Lokale Artikelnummer::
BOSSBS-5499R
Beschreibung:
MyoD1 belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. Myod1 is essential for repair of damaged tissue. It activates its own transcription which may stabilize commitment to myogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8233R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8233R-A488
Lokale Artikelnummer::
BOSSBS-8233R-A488
Beschreibung:
FRMPD1 has been identified as a regulatory binding partner of activator of G-protein signaling 3 (AGS3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5881R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5881R-CY3
Lokale Artikelnummer::
BOSSBS-5881R-CY3
Beschreibung:
COL20A1 is a probable collagen protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3858R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3858R
Lokale Artikelnummer::
BOSSBS-3858R
Beschreibung:
Anti-SH2D2A Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2399R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2399R-CY7
Lokale Artikelnummer::
BOSSBS-2399R-CY7
Beschreibung:
Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11769R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11769R-A680
Lokale Artikelnummer::
BOSSBS-11769R-A680
Beschreibung:
The majority of mitochondrial-directed proteins are encoded by the nuclear genome and are transported to the mitochondria via regulated processes involving the mitochondrial Tom and Tim proteins. The mitochondrial Tim protein family is comprised of a large group of evolutionarily conserved proteins that are found in most eukaryotes. Import of nuclear-encoded precursor proteins into and across the mitochondrial inner membrane is mediated by two distinct complexes, the Tim23 complex and the Tim22 complex, which differ in their substrate specificity. Defects in Tim proteins are implicated in several neuro-degenerative diseases, suggesting important roles for Tim proteins in development and health. Tim8A and Tim8B, which map to human chromosomes Xq22.1 and 11q23.1-q23.2, respectively, are conserved proteins of the mitochondrial intermembrane space, which are organized in hetero-oligomeric complex with Tim13. Tim8A is highly expressed in fetal and adult brain. Tim8A is mutated in deafness dystonia syndrome, a novel type of disease that causes severe neurological defects, thought to be caused by a defective mitochondrial protein transport system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2311R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2311R-A350
Lokale Artikelnummer::
BOSSBS-2311R-A350
Beschreibung:
Classical swine fever(CSF) is a kind of acute and intense contagious disease in swine, it material damages swine industry. CSF could cause swine appearing disseminated hemorrhage in systemic organ and tissue, degeneration and necrosis in small vascular and capillary endothelial cells. Classical swine fever virus (CSFV) belongs to genera Pestivirus, family Flaviviridae, it’s genome total length is 12.3Kb,including a big ORF, encoding 11 structural and nonstructural proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9526R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9526R-FITC
Lokale Artikelnummer::
BOSSBS-9526R-FITC
Beschreibung:
Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12050R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12050R-A647
Lokale Artikelnummer::
BOSSBS-12050R-A647
Beschreibung:
Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to serotonin. SR-2A has a specific role in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia. SR-2B is expressed in embryonic and adult cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders. SR-2C is thought to mediate the effects of atypical antipsychotic drugs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0081R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0081R-CY5
Lokale Artikelnummer::
BOSSBS-0081R-CY5
Beschreibung:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0787R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0787R-CY5.5
Lokale Artikelnummer::
BOSSBS-0787R-CY5.5
Beschreibung:
Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC â… molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9254R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9254R-A750
Lokale Artikelnummer::
BOSSBS-9254R-A750
Beschreibung:
E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15395R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15395R-A647
Lokale Artikelnummer::
BOSSBS-15395R-A647
Beschreibung:
GPS2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5659R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5659R-CY7
Lokale Artikelnummer::
BOSSBS-5659R-CY7
Beschreibung:
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Preis auf Anfrage
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