2-Aminoadamantane-2-carboxylic+acid
Artikel-Nr:
(68279-1L)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
68279-1L
Lokale Artikelnummer::
SUPL68279-1L
Beschreibung:
Schwefelsäure (Konzentrat) 0.1 mol/l (0.2 N) in wässriger Lösung für die Ionenchromatographie, Supelco®
VE:
1 * 1 L
Artikel-Nr:
(BLDPBD258361-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD258361-5G
Lokale Artikelnummer::
BLDPBD258361-5G
Beschreibung:
3-Hydroxythietane 1,1-dioxide 95%
VE:
1 * 5 g
Artikel-Nr:
(28256.296)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC28256.296
Beschreibung:
Schwefel ≥99%, Blume, TECHNICAL
VE:
1 * 1 kg
Artikel-Nr:
(1.09286.2500)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.09286.2500
Lokale Artikelnummer::
MERC1.09286.2500
Beschreibung:
Schwefelsäure 40%, Supelco®
VE:
1 * 2,5 L
Artikel-Nr:
(BOSSBS-15482R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15482R-A680
Lokale Artikelnummer::
BOSSBS-15482R-A680
Beschreibung:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15482R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15482R-A488
Lokale Artikelnummer::
BOSSBS-15482R-A488
Beschreibung:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
VE:
1 * 100 µl
Artikel-Nr:
(5802-15)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR5802-15
Beschreibung:
Schwefelsäure ≥ 95% ≥95%, Finyte® für Mikroelektronik, J.T.Baker®
VE:
1 * 15 lb
Lieferant:
MP Biomedicals
Beschreibung:
L-α-Glycerophosphoryl Choline, Cadmium Chloride Complex (aus Eigelb) ∼98%, weißes Pulver
Lieferant:
VWR Chemicals
Beschreibung:
Schwefelsäure ≥98%, AnalaR NORMAPUR® analytisches Reagens
Artikel-Nr:
(BLDPBD64651-25G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD64651-25G
Lokale Artikelnummer::
BLDPBD64651-25G
Beschreibung:
2,2'-Bipyridyl-1,1'-dioxide 98%
VE:
1 * 25 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4,4'-Bipyridine -1,1'-dioxide 98%
Artikel-Nr:
(PEA1900-20ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
PEA1900-20ML
Lokale Artikelnummer::
SUPLPEA1900-20ML
Beschreibung:
Sulfur Dioxide in Impinger Solution, Supelco®, Proficiency Testing Material, : N/A
VE:
1 * 20 mL
Artikel-Nr:
(BLDPBD01092179-50M)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD01092179-50M
Lokale Artikelnummer::
BLDPBD01092179-50M
Beschreibung:
(R)-4-Hydroxythiochroman 1,1-dioxide 95%
VE:
1 * 50 mg
Artikel-Nr:
(6501.2500)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC6501.2500
Beschreibung:
Schwefelsäure 1 mol/l (2 N) in wässriger Lösung für die biopharmazeutische Produktion
VE:
1 * 2,5 L
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Propargylthiomorpholine-1,1-dioxide
Artikel-Nr:
(BOSSBS-15482R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15482R-A555
Lokale Artikelnummer::
BOSSBS-15482R-A555
Beschreibung:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
VE:
1 * 100 µl
Preis auf Anfrage
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