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4,4-Dimethylcyclohexa-1,5-dienylborons\\\\\\\\u00E4ure+Mononatriu
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4,4-Dimethylcyclohexa-1,5-dienylborons\\\\\\\\u00E4ure+Mononatriu
Artikel-Nr:
(PROONIST-2182)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
NIST-2182
Lokale Artikelnummer::
PROONIST-2182
Beschreibung:
HEPES Natriumsalz
VE:
1 * 60 g
Lieferant:
Sigma-Aldrich
Beschreibung:
HEPES Natriumsalz, Sigma-Aldrich®
Artikel-Nr:
(PRSI96-108)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-108
Lokale Artikelnummer::
PRSI96-108
Beschreibung:
Cluster of differentiation 14 (CD14), is a cell surface glycoprotein, and is a is a component of the innate immune system. CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists in two forms. Either it is anchored into the membrane by a glycosylphosphatidylinositol tail (mCD14) or it appears in a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48 kDa) or is directly secreted from intracellular vesicles (56 kDa). CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns. CD14+ cells are monocytes that can differentiate into a host of different cells. CD14 has been shown to interact with Lipopolysaccharide-binding protein.
VE:
1 * 100 µG
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
HEPES Natriumsalz, Millipore®
Lieferant:
Sigma-Aldrich
Beschreibung:
HEPES (2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethansulfonsäure), Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
HEPES Natriumsalz, Sigma-Aldrich®
Artikel-Nr:
(PRSI30-425)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-425
Lokale Artikelnummer::
PRSI30-425
Beschreibung:
TYMS catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-47 CR601528.1 1-47 48-1099 X02308.1 14-1065 1100-1603 BC083512.1 1067-1570
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-791)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-791
Lokale Artikelnummer::
PRSI29-791
Beschreibung:
Mutations in GNAS gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.This gene has a highly complex imprinted expression pattern. It encodes maternally, paternally, and biallelically expressed proteins which are derived from alternatively spliced transcripts with alternate 5' exons. Each of the upstream exons is within a differentially methylated region, commonly found in imprinted genes. However, the close proximity (14 kb) of two oppositely expressed promoter regions is unusual. In addition, one of the alternate 5' exons introduces a frameshift relative to the other transcripts, resulting in one isoform which is structurally unrelated to the others. An antisense transcript exists, and may regulate imprinting in this region. Mutations in this gene result in pseudohypoparathyroidism type 1a (PHP1a), which has an atypical autosomal dominant inheritance pattern requiring maternal transmission for full penetrance. There are RefSeqs representing four transcript variants of this gene. Other transcript variants including four additional exons have been described; however, their full length sequences have not been determined.
VE:
1 * 100 µG
Artikel-Nr:
(229101-50)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
229101-50
Lokale Artikelnummer::
CALB229101-50
Beschreibung:
Natriumcholat, Millipore®
VE:
1 * 50 g
Lieferant:
CHROMACOL
Beschreibung:
Chromacol™, Chromatographieampullen-Verschlüsse, Aluminium, Ø: 8 mm, Silberfarbene Bördelkappe, 4 mm Loch, Typ: 8-AC-ST15, Härte: 50° shore, Septum: Weißes Silikon/rotes PTFE, Stärke: 1,3 mm
Artikel-Nr:
(PRSI79-456)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-456
Lokale Artikelnummer::
PRSI79-456
Beschreibung:
Required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at 'Ser-178' and 'Thr-507' and phosphorylation of CDC25C at 'Ser-216' creates binding sites for 14-3-3 proteins which inhibit CDC25A and CDC25C. Phosphorylation of CDC25A at 'Ser-76', 'Ser-124', 'Ser-178', 'Ser-279' and 'Ser-293' promotes proteolysis of CDC25A. Inhibition of CDC25 activity leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. Binds to and phosphorylates RAD51 at 'Thr-309', which may enhance the association of RAD51 with chromatin and promote DNA repair by homologous recombination. Binds to and phosphorylates TLK1 at 'Ser-743', which prevents the TLK1-dependent phosphorylation of the chromatin assembly factor ASF1A. This may affect chromatin assembly during S phase or DNA repair. May also phosphorylate multiple sites within the C-terminus of TP53, which promotes activation of TP53 by acetylation and enhances suppression of cellular proliferation.
VE:
1 * 100 µG
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
HEPES (2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethansulfonsäure) freie Säure, ULTROL®, Millipore®
Artikel-Nr:
(UPTIUP04594A)
Lieferant:
Uptima
Hersteller-Artikelnummer::
UP04594A
Lokale Artikelnummer::
UPTIUP04594A
Beschreibung:
N-Hydroxysuccinimid
VE:
1 * 500 mg
Lieferant:
Avantor
Beschreibung:
Säulenbefüllungen auf Basis von Siliziumdioxid mit hoher Reinigungsleistung für stark hydrophile Peptide und Proteine, basierend auf hydrophoben Eigenschaften und Molekülformen.
Lieferant:
Alfa Aesar
Beschreibung:
HEPES (2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethansulfonsäure) ≥99% (Trockenmasse), Pulver, ultrarein
Lieferant:
B. Braun
Beschreibung:
Kanülenrohr aus nicht rostendem Chrom-Nickelstahl mit extrem glatter Oberfläche und feindosierter Silikonbeschichtung, transparenter Luer-Lock-Ansatz aus PP.
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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