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2-Brom-4,5-dimethoxybenzoes\u00E4ure
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2-Brom-4,5-dimethoxybenzoes\u00E4ure
Artikel-Nr:
(BOSSBS-4131R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4131R-A488
Lokale Artikelnummer::
BOSSBS-4131R-A488
Beschreibung:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7851R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7851R-CY3
Lokale Artikelnummer::
BOSSBS-7851R-CY3
Beschreibung:
Microtubules, polymers of alpha and beta tubulin subunits,form the mitotic spindle of a dividing cell and help to organizemembranous organelles during interphase. Katanin is a heterodimerthat consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDaaccessory protein (p80 subunit B 1). The p60 subunit acts to severand disassemble microtubules, while the p80 subunit targets theenzyme to the centrosome. Katanin is a member of the AAA family ofATPases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4131R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4131R-CY5.5
Lokale Artikelnummer::
BOSSBS-4131R-CY5.5
Beschreibung:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5328R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5328R-A647
Lokale Artikelnummer::
BOSSBS-5328R-A647
Beschreibung:
HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1319R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1319R-A555
Lokale Artikelnummer::
BOSSBS-1319R-A555
Beschreibung:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9243R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9243R-FITC
Lokale Artikelnummer::
BOSSBS-9243R-FITC
Beschreibung:
RNF20 is an E3 ubiquitin ligase protein that mediates monoubiquitination of histone H2B and the methylation of histone H3. It forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. It is required for transcriptional activation of Hox genes. It is recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4131R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4131R-A680
Lokale Artikelnummer::
BOSSBS-4131R-A680
Beschreibung:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9243R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9243R-A680
Lokale Artikelnummer::
BOSSBS-9243R-A680
Beschreibung:
RNF20 is an E3 ubiquitin ligase protein that mediates monoubiquitination of histone H2B and the methylation of histone H3. It forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. It is required for transcriptional activation of Hox genes. It is recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2081R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2081R-CY3
Lokale Artikelnummer::
BOSSBS-2081R-CY3
Beschreibung:
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6800R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6800R-CY3
Lokale Artikelnummer::
BOSSBS-6800R-CY3
Beschreibung:
Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3733R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3733R-CY5
Lokale Artikelnummer::
BOSSBS-3733R-CY5
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2081R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2081R-CY7
Lokale Artikelnummer::
BOSSBS-2081R-CY7
Beschreibung:
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7779R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7779R-CY7
Lokale Artikelnummer::
BOSSBS-7779R-CY7
Beschreibung:
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3123R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3123R-CY3
Lokale Artikelnummer::
BOSSBS-3123R-CY3
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9301R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9301R-HRP
Lokale Artikelnummer::
BOSSBS-9301R-HRP
Beschreibung:
SAS-6 (spindle assembly abnormal protein 6 homolog, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6. SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain. LK4, SAS-6, CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures. SAS-6 associates only transiently with nascent procentrioles, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles. SAS-6 is necessary for procentriole formation in human cell lines and is localized asymmetrically next to the centriole at the onset of procentriole formation. SAS-6 levels oscillate during the cell cycle; it is degraded in mitosis starting at anaphase, and it accumulates again at the end of the following G1 phase. The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation. Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1864R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1864R-A350
Lokale Artikelnummer::
BOSSBS-1864R-A350
Beschreibung:
SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in the placenta, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency. SerpinB2 also inhibits tissue plasminogen activator (t-PA), but with micromolar efficiency, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator. The structure of PAI-2 is not terribly similar to PAI-1, however, which is an E clade serpin. SerpinB2 is made by many cell types, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein. SerpinB2 is found in saliva, secreted by gingival fibroblasts, and in the skin. SerpinB2 levels are elevated in serum during pregnancy, and in leukemia, breast cancer and ovarian cancer, although it was lowered in some cancers.A shorter SerpinB2 isoform of 382 amino acids, has been reported, with a predicted mass of 43.1 kDa and a pI of 5.69. The shorter form has a deletion just after the start of the mature protein, but it is unclear what the relative production and distribution is for the shorter sequence.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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