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Tris(2,2,2-trifluoroethyl)+Phosphate
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Tris(2,2,2-trifluoroethyl)+Phosphate
Artikel-Nr:
(PROONIST-694)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
NIST-694
Lokale Artikelnummer::
PROONIST-694
Beschreibung:
This standard material is intended to use in validating analytical methods and in calibrating instruments used in the analysis of phosphate rock, fertilisers and similar materials.
VE:
1 * 90 g
Lieferant:
Alfa Aesar
Beschreibung:
Waschpuffer, TRIS-buffered saline (TBS, 20X), with 2% Tween 20
Artikel-Nr:
(BOSSBS-2125R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2125R-CY5.5
Lokale Artikelnummer::
BOSSBS-2125R-CY5.5
Beschreibung:
E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Through their polyubiquitination, may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, FLT3, MET and CXCR4. May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174). May also play a role in the endosomal recycling of IGF2R, the cation-independent mannose-6-phosphate receptor (PubMed:24275455). By ubiquitinating CDKN1A/p21 and targeting it for degradation, may also promote cell proliferation (PubMed:23026136). May monoubiquitinate AICDA (PubMed:23277564).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2125R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2125R-A488
Lokale Artikelnummer::
BOSSBS-2125R-A488
Beschreibung:
E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Through their polyubiquitination, may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, FLT3, MET and CXCR4. May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174). May also play a role in the endosomal recycling of IGF2R, the cation-independent mannose-6-phosphate receptor (PubMed:24275455). By ubiquitinating CDKN1A/p21 and targeting it for degradation, may also promote cell proliferation (PubMed:23026136). May monoubiquitinate AICDA (PubMed:23277564).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2125R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2125R-CY3
Lokale Artikelnummer::
BOSSBS-2125R-CY3
Beschreibung:
E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Through their polyubiquitination, may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, FLT3, MET and CXCR4. May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174). May also play a role in the endosomal recycling of IGF2R, the cation-independent mannose-6-phosphate receptor (PubMed:24275455). By ubiquitinating CDKN1A/p21 and targeting it for degradation, may also promote cell proliferation (PubMed:23026136). May monoubiquitinate AICDA (PubMed:23277564).
VE:
1 * 100 µl
Artikel-Nr:
(710-0989)
Lieferant:
MBV
Hersteller-Artikelnummer::
04.4910.01
Lokale Artikelnummer::
MBVA04.4910.01
Beschreibung:
Tri-Clamp, Für: MAS-100 Iso NT®
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-13667R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13667R-A647
Lokale Artikelnummer::
BOSSBS-13667R-A647
Beschreibung:
Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12039R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12039R-A350
Lokale Artikelnummer::
BOSSBS-12039R-A350
Beschreibung:
GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12039R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12039R-FITC
Lokale Artikelnummer::
BOSSBS-12039R-FITC
Beschreibung:
GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13667R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13667R-A555
Lokale Artikelnummer::
BOSSBS-13667R-A555
Beschreibung:
Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13667R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13667R-HRP
Lokale Artikelnummer::
BOSSBS-13667R-HRP
Beschreibung:
Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).
VE:
1 * 100 µl
Artikel-Nr:
(648315-100)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
648315-100
Lokale Artikelnummer::
CALB648315-100
Beschreibung:
Cloning Buffer, TRIS Pufferlösung pH 7,4 (0,1 mol/l)
VE:
1 * 100 mL
Artikel-Nr:
(SIALT5912-1L)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
T5912-1L
Lokale Artikelnummer::
SIALT5912-1L
Beschreibung:
Washing buffer for alkaline phosphatase or peroxidase conjugates in Western blotting.
VE:
1 * 1 L
Lieferant:
MP Biomedicals
Beschreibung:
50 mg/ml, clear colourless to slightly yellow solution.
Artikel-Nr:
(USBI138217)
Lieferant:
US Biological
Hersteller-Artikelnummer::
138217
Lokale Artikelnummer::
USBI138217
Beschreibung:
Anti-PGS1 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-2125R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2125R-A555
Lokale Artikelnummer::
BOSSBS-2125R-A555
Beschreibung:
E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Through their polyubiquitination, may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, FLT3, MET and CXCR4. May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174). May also play a role in the endosomal recycling of IGF2R, the cation-independent mannose-6-phosphate receptor (PubMed:24275455). By ubiquitinating CDKN1A/p21 and targeting it for degradation, may also promote cell proliferation (PubMed:23026136). May monoubiquitinate AICDA (PubMed:23277564).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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