Methyl+6-(fluoromethyl)picolinate
Artikel-Nr:
(BOSSBS-1178R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1178R-A680
Lokale Artikelnummer::
BOSSBS-1178R-A680
Beschreibung:
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12420R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12420R-A680
Lokale Artikelnummer::
BOSSBS-12420R-A680
Beschreibung:
14-3-3 are activates tyrosine and tryptophan hydroxylases in the presence of Ca²⁺/calmodulin-dependent protein kinase II, and strongly activates protein kinase C. Is probably a multifunctional regulator of the cell Signalling processes mediated by both kinases. Activates the ADP-ribosyltransferase (exoS) activity of bacterial origin. 14-3-3 proteins are localised in neurons, and are axonally transported to the nerve terminals. They may be also present, at lower levels, in various other eukaryotic tissues. It belongs to the 14-3-3 family. This antibody is reactive with 14-3-3 Alpha/Beta/Gamma/Delta/Epsilon.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5974R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5974R-FITC
Lokale Artikelnummer::
BOSSBS-5974R-FITC
Beschreibung:
SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0494R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0494R-A750
Lokale Artikelnummer::
BOSSBS-0494R-A750
Beschreibung:
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5974R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5974R-A350
Lokale Artikelnummer::
BOSSBS-5974R-A350
Beschreibung:
SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6070R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6070R-CY3
Lokale Artikelnummer::
BOSSBS-6070R-CY3
Beschreibung:
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11802R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11802R-FITC
Lokale Artikelnummer::
BOSSBS-11802R-FITC
Beschreibung:
The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-D is a 710 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-D mediates the Na+-independent transport of vasopressin, prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II and other organic anions, but not estrone-3-sulfate, DPDPE, taurocholate, DHEAS or digoxin. OATP-D is ubiquitously expressed with highest levels present in leukocytes and spleen. OATP-D is expressed as four isoforms produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11802R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11802R-CY7
Lokale Artikelnummer::
BOSSBS-11802R-CY7
Beschreibung:
The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-D is a 710 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-D mediates the Na+-independent transport of vasopressin, prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II and other organic anions, but not estrone-3-sulfate, DPDPE, taurocholate, DHEAS or digoxin. OATP-D is ubiquitously expressed with highest levels present in leukocytes and spleen. OATP-D is expressed as four isoforms produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9302R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9302R-CY3
Lokale Artikelnummer::
BOSSBS-9302R-CY3
Beschreibung:
Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination. The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S. cerevisiae. The DSBs are located mostly in promoter regions, where the chromatin is in an open configuration, and cluster in domains along the chromosome. Expression of the Spo11 is detected mainly in the testis, in agreement with its predicted function in the initiation of meiotic recombination. Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility.
VE:
1 * 100 µl
Lieferant:
MP Biomedicals
Beschreibung:
Ferrous ammonium sulphate is often employed as an analytical standard, and has been used in a variety of other applications from nanomaterials to general redox reactions. It is used for titration purposes.
Lieferant:
Tonbo Biosciences
Beschreibung:
The 2.4G2 antibody is specific for a common epitope found in the extracellular regions of mouse Fc-receptors Fc-gamma II (CD32) and Fc-gamma III (CD16). As these are receptors for the Fc portion of mouse IgG, they may also bind laboratory antibody preparations and products used in a variety of cell analysis protocols such as flow cytometry, immunohistochemistry and functional cell assays. The 2.4G2 antibody is therefore widely used as a pre-treatment reagent to block binding of specific antibodies of interest, e.g. fluorescently conjugated antibodies, to Fc receptors via their Fc domains and contributing to “non-specific” staining.
Lieferant:
Sigma-Aldrich
Beschreibung:
Cadmium(II)carbonat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-13095R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13095R-CY7
Lokale Artikelnummer::
BOSSBS-13095R-CY7
Beschreibung:
Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitment of XAB2, HMGN1 and TCEA1/TFIIS to a transcription-coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2566R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2566R-CY5
Lokale Artikelnummer::
BOSSBS-2566R-CY5
Beschreibung:
Dectin 2 is a type II transmembrane protein that is a member of the C type lectin superfamily. In mouse, dectin 2 is predominantly expressed on tissue macrophages and some dendritic cells. Significant expression of Dectin 2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin 2 but transient up regulation of expression has been demonstrated on monocytes at sites of inflammation. The function of dectin 2 has not been fully determined but studies suggest a possible role in immune surveillance.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1178R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1178R-CY5.5
Lokale Artikelnummer::
BOSSBS-1178R-CY5.5
Beschreibung:
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0494R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0494R-CY5
Lokale Artikelnummer::
BOSSBS-0494R-CY5
Beschreibung:
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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