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beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
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beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
Artikel-Nr:
(BOSSBS-11044R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11044R-A555
Lokale Artikelnummer::
BOSSBS-11044R-A555
Beschreibung:
Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; this function seems to redundant with the AP-2 complex and seems to require DAB2 binding to endocytosis accessory EH domain-containing proteins such as EPS15, EPS15L1 and ITSN1. Involved in endocytosis of cystic fibrosis transmembrane conductance regulator/CFTR. Involved in endocytosis of megalin/LRP2 lipoprotein receptor during embryonal development. Required for recycling of the TGF-beta receptor. Involved in CFTR trafficking to the late endosome. Involved in several receptor-mediated signaling pathways. Involved in TGF-beta receptor signaling and facilitates phosphorylation of the signal transducer SMAD2. Mediates TFG-beta-stimulated JNK activation. May inhibit the canoniocal Wnt/beta-catenin signaling pathway by stabilizing the beta-catenin destruction complex through a competing association with axin preventing its dephosphorylation through protein phosphatase 1 (PP1). Sequesters LRP6 towards clathrin-mediated endocytosis, leading to inhibition of Wnt/beta-catenin signaling. May activate non-canonical Wnt signaling.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
β-Chlorpropiophenon 98%
Artikel-Nr:
(BOSSBS-2475R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2475R-A555
Lokale Artikelnummer::
BOSSBS-2475R-A555
Beschreibung:
MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD 5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor 1 (CC CKR1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2475R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2475R-A488
Lokale Artikelnummer::
BOSSBS-2475R-A488
Beschreibung:
MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD 5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor 1 (CC CKR1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5717R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5717R-A647
Lokale Artikelnummer::
BOSSBS-5717R-A647
Beschreibung:
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR4893-500G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR4893-500G
Lokale Artikelnummer::
APOSOR4893-500G
Beschreibung:
2,4-Dihydroxybenzoesäure 97%
VE:
1 * 500 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
β-D-Glucopyranosyl-glycolaldehyde ≥95%
Artikel-Nr:
(PRSI77-033)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-033
Lokale Artikelnummer::
PRSI77-033
Beschreibung:
The NIB42 monoclonal antibody specifically reacts with human interferon gamma, a multifunctional cytokine that is produced mainly by activated T and NK cells. Interferon gamma has anti-viral and anti-parasitic properties and plays an important role in the activation, growth, and differentiation of macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. The NIB42 antibody neutralizes IFN-gamma.
VE:
1 * 100 Tests
New Product
Lieferant:
Alfa Aesar
Beschreibung:
Estradiol, (max. 3% H₂O) 99% (Trockengewicht)
Artikel-Nr:
(ROCK610-456-C46)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
610-456-C46
Lokale Artikelnummer::
ROCK610-456-C46
Beschreibung:
The emission spectra for this ATTO conjugate matches the principle output wavelengths of most common fluorescence instrumentation.
VE:
1 * 500 µG
Artikel-Nr:
(BOSSBS-11058R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11058R-A647
Lokale Artikelnummer::
BOSSBS-11058R-A647
Beschreibung:
May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BWRLBS4345)
Lieferant:
Bioworld Technology
Hersteller-Artikelnummer::
BS4345
Lokale Artikelnummer::
BWRLBS4345
Beschreibung:
Synthetic phosphopeptide derived from human PKAalpha around the phosphorylation site of Threonine 197.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-2937R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2937R-HRP
Lokale Artikelnummer::
BOSSBS-2937R-HRP
Beschreibung:
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-O-Allyl-β-D-glucopyranose ≥97%
Artikel-Nr:
(BOSSBS-8299R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8299R-A750
Lokale Artikelnummer::
BOSSBS-8299R-A750
Beschreibung:
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerisation, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3813R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3813R-A488
Lokale Artikelnummer::
BOSSBS-3813R-A488
Beschreibung:
UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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