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beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
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beta-Methyl-gamma-octanolactone+(mixture+of+isomers)
Lieferant:
Alfa Aesar
Beschreibung:
β-Naphthoflavon ≥98%
Artikel-Nr:
(BOSSBS-3253R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3253R-A555
Lokale Artikelnummer::
BOSSBS-3253R-A555
Beschreibung:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9407R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9407R-A750
Lokale Artikelnummer::
BOSSBS-9407R-A750
Beschreibung:
The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican, Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGF beta. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TGF-beta-1 or TGF-beta-2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3253R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3253R-FITC
Lokale Artikelnummer::
BOSSBS-3253R-FITC
Beschreibung:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3253R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3253R-A488
Lokale Artikelnummer::
BOSSBS-3253R-A488
Beschreibung:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11260R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11260R-HRP
Lokale Artikelnummer::
BOSSBS-11260R-HRP
Beschreibung:
Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11260R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11260R-FITC
Lokale Artikelnummer::
BOSSBS-11260R-FITC
Beschreibung:
Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation. Effects of TGF-Beta family ligands are mediated by Smad proteins. The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. SNIP1 potently inhibits the activity of NF-kappa B, which binds the C/H1 domain of CBP/p300, by competing for the binding site. SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation. SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,6-Anhydro-2-deoxy-2-iodo-β-D-glucopyranose ≥98%
Artikel-Nr:
(ABCAAB308822-200)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB308822-200
Lokale Artikelnummer::
ABCAAB308822-200
Beschreibung:
Anti-Topoisomerase II alpha+Topoisomerase II beta/TOP2B Rabbit Monoclonal Antibody [clone: EPR5377] (Alkaline Phosphatase)
VE:
1 * 200 µl
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BLDPBD2659-25G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD2659-25G
Lokale Artikelnummer::
BLDPBD2659-25G
Beschreibung:
Gastrodin 98%
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-4286R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4286R-A647
Lokale Artikelnummer::
BOSSBS-4286R-A647
Beschreibung:
Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4286R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4286R-A750
Lokale Artikelnummer::
BOSSBS-4286R-A750
Beschreibung:
Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organisation and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4286R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4286R-FITC
Lokale Artikelnummer::
BOSSBS-4286R-FITC
Beschreibung:
Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3253R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3253R-CY5.5
Lokale Artikelnummer::
BOSSBS-3253R-CY5.5
Beschreibung:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(SARP5445307H8G-OOA)
Lieferant:
Sartorius
Hersteller-Artikelnummer::
5445307H8G-OOA
Lokale Artikelnummer::
SARP5445307H8G-OOA
Beschreibung:
Gebrauchsfertige Einwegkapseln für die Sterilfiltration im Labormaßstab oder für Versuche zur Filtrierbarkeit im kleinen Maßstab.
VE:
1 * 4 ST
Artikel-Nr:
(BOSSBS-10368R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10368R-CY3
Lokale Artikelnummer::
BOSSBS-10368R-CY3
Beschreibung:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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